Preclinical Characterization of the Radioimmunoconjugate
Animals
Antibodies, Monoclonal
/ immunology
Cadherins
/ immunology
Cell Line, Tumor
Cell Transformation, Neoplastic
Gene Expression Regulation, Neoplastic
/ immunology
Immunoconjugates
/ chemistry
Indium Radioisotopes
/ chemistry
Isotope Labeling
Macaca fascicularis
Male
Mice
Radioimmunotherapy
Tissue Distribution
Yttrium Radioisotopes
/ chemistry
CDH3
antibody, dosimetry
targeted radionuclide therapy
theranostics
Journal
Journal of nuclear medicine : official publication, Society of Nuclear Medicine
ISSN: 1535-5667
Titre abrégé: J Nucl Med
Pays: United States
ID NLM: 0217410
Informations de publication
Date de publication:
02 2021
02 2021
Historique:
received:
08
04
2020
accepted:
26
06
2020
pubmed:
2
8
2020
medline:
30
4
2021
entrez:
2
8
2020
Statut:
ppublish
Résumé
P-cadherin is overexpressed in various cancers and can be a target for radioimmunotherapy. We investigated the preclinical pharmacokinetics and pharmacology of FF-21101, an
Identifiants
pubmed: 32737245
pii: jnumed.120.245837
doi: 10.2967/jnumed.120.245837
pmc: PMC8679590
doi:
Substances chimiques
Antibodies, Monoclonal
0
Cadherins
0
Immunoconjugates
0
Indium Radioisotopes
0
Yttrium Radioisotopes
0
Yttrium-90
1K8M7UR6O1
Indium-111
E9NGC49E0T
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
232-239Informations de copyright
© 2021 by the Society of Nuclear Medicine and Molecular Imaging.
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