Implications of TP53 allelic state for genome stability, clinical presentation and outcomes in myelodysplastic syndromes.
Alleles
Cohort Studies
DNA Copy Number Variations
/ genetics
DNA Mutational Analysis
Female
Gene Frequency
Genomic Instability
/ genetics
Humans
Loss of Heterozygosity
/ genetics
Male
Mutation
Myelodysplastic Syndromes
/ diagnosis
Phenotype
Prognosis
Survival Analysis
Treatment Outcome
Tumor Suppressor Protein p53
/ genetics
Journal
Nature medicine
ISSN: 1546-170X
Titre abrégé: Nat Med
Pays: United States
ID NLM: 9502015
Informations de publication
Date de publication:
10 2020
10 2020
Historique:
received:
27
11
2019
accepted:
07
07
2020
pubmed:
5
8
2020
medline:
15
12
2020
entrez:
5
8
2020
Statut:
ppublish
Résumé
Tumor protein p53 (TP53) is the most frequently mutated gene in cancer
Identifiants
pubmed: 32747829
doi: 10.1038/s41591-020-1008-z
pii: 10.1038/s41591-020-1008-z
pmc: PMC8381722
mid: NIHMS1715889
doi:
Substances chimiques
TP53 protein, human
0
Tumor Suppressor Protein p53
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
1549-1556Subventions
Organisme : Blood Cancer UK
ID : 13042
Pays : United Kingdom
Organisme : NCI NIH HHS
ID : K12 CA184746
Pays : United States
Organisme : NCI NIH HHS
ID : P30 CA008748
Pays : United States
Organisme : Howard Hughes Medical Institute
Pays : United States
Commentaires et corrections
Type : CommentIn
Type : ErratumIn
Type : ErratumIn
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