Imaging Analysis for Cholesteatoma Extension to the Perilymphatic Space in Labyrinth Fistulae.


Journal

The Laryngoscope
ISSN: 1531-4995
Titre abrégé: Laryngoscope
Pays: United States
ID NLM: 8607378

Informations de publication

Date de publication:
04 2021
Historique:
received: 20 04 2020
revised: 16 07 2020
accepted: 21 07 2020
pubmed: 18 8 2020
medline: 10 4 2021
entrez: 18 8 2020
Statut: ppublish

Résumé

Disturbed perilymph behind a labyrinth fistula can lead to hearing deterioration; thus, delicate manipulation is required during surgery for cholesteatomatous fistulae with matrix extension to the perilymphatic space (EPS). However, it remains challenging to identify the EPS preoperatively. This study aimed to evaluate the diagnostic value of computed tomography (CT) for preoperative prediction of the EPS of cholesteatomatous fistulae. Retrospective study. We included serial high-resolution CT images showing a cholesteatomatous bone defect in the lateral semicircular canal (LSC) requiring mastoidectomy. CT and intraoperative findings were analyzed retrospectively. Using axial CT planes, we evaluated the length and angle between the margins of bone defects. Receiver operating characteristic (ROC) curves were constructed to determine the cutoff points. We extracted data from 30 bone defects, of which six (20.0%) showed EPS intraoperatively. Bone defects with EPS (n = 6) had significantly greater length and angle values than those without EPS (n = 24) (P < .001 for both, Wilcoxon rank sum test). For length and angle, the area under the curve was 0.944 (95% confidence interval [CI]: 0.858-1.000) and 0.951 (95% CI: 0.875-1.000), respectively, according to the ROC analysis, and the optimal cutoff values were 3.65 mm and 71.6°, respectively, with 100% sensitivity and 91.67% specificity for both. Results demonstrated that a length >3.65 mm and an angle >71.6° for LSC bone defects on axial CT images are reliable diagnostic markers of EPS. Preoperative high-resolution CT analysis can provide surgeons with a more conscientious preparation for handling deeper labyrinth fistulae. 4 Laryngoscope, 131:E1301-E1307, 2021.

Identifiants

pubmed: 32804413
doi: 10.1002/lary.29016
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

E1301-E1307

Informations de copyright

© 2020 American Laryngological, Rhinological and Otological Society Inc, "The Triological Society" and American Laryngological Association (ALA).

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Auteurs

Masaomi Motegi (M)

Department of Otorhinolaryngology, The Jikei University School of Medicine, Tokyo, Japan.

Yutaka Yamamoto (Y)

Department of Otorhinolaryngology, The Jikei University School of Medicine, Tokyo, Japan.

Taisuke Akutsu (T)

Department of Otorhinolaryngology, The Jikei University School of Medicine, Tokyo, Japan.

Hideomi Yamauchi (H)

Department of Radiology, The Jikei University School of Medicine, Tokyo, Japan.

Sho Kurihara (S)

Department of Otorhinolaryngology, The Jikei University School of Medicine, Tokyo, Japan.

Masahiro Takahashi (M)

Department of Otorhinolaryngology, The Jikei University School of Medicine, Tokyo, Japan.

Tsunetaro Morino (T)

Department of Otorhinolaryngology, The Jikei University School of Medicine, Tokyo, Japan.

Manabu Komori (M)

Department of Otorhinolaryngology, The Jikei University School of Medicine, Tokyo, Japan.

Kazuhisa Yamamoto (K)

Department of Otorhinolaryngology, The Jikei University School of Medicine, Tokyo, Japan.

Yuika Sakurai (Y)

Department of Otorhinolaryngology, The Jikei University School of Medicine, Tokyo, Japan.

Hiroya Ojiri (H)

Department of Radiology, The Jikei University School of Medicine, Tokyo, Japan.

Hiromi Kojima (H)

Department of Otorhinolaryngology, The Jikei University School of Medicine, Tokyo, Japan.

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