Risk Factors for Postprocedural Arterial Ischemic Stroke in Children With Cardiac Disease.
Adolescent
Brain Ischemia
/ epidemiology
Cardiac Surgical Procedures
/ adverse effects
Child
Child, Preschool
Delayed Diagnosis
Female
Heart Diseases
/ complications
Hemodynamics
Humans
Infections
/ complications
Male
Postoperative Complications
/ epidemiology
Prospective Studies
Registries
Risk Factors
Stroke
/ epidemiology
Switzerland
/ epidemiology
Young Adult
hemodynamics
hypotension
incidence
infections
low cardiac output
Journal
Stroke
ISSN: 1524-4628
Titre abrégé: Stroke
Pays: United States
ID NLM: 0235266
Informations de publication
Date de publication:
09 2020
09 2020
Historique:
pubmed:
20
8
2020
medline:
31
10
2020
entrez:
20
8
2020
Statut:
ppublish
Résumé
Cardiac pathologies are the second most frequent risk factor (RF) in children with arterial ischemic stroke (AIS). This study aimed to analyze RFs for AIS in children with cardiac disease and cardiac intervention. Data were drawn from the Swiss Neuropediatric Stroke Registry. Patients with cardiac disease and postprocedural AIS registered from 2000 until 2015 were analyzed for the cause of cardiac disease and for potential RFs. Forty-seven out of 78 children with cardiac disease had a cardiac intervention. Of these, 36 presented a postprocedural AIS. Median time from cardiac intervention to symptom onset was 4 days (interquartile range, 2-8.5); time to diagnosis of AIS was 2 days (interquartile range, 0-5.8). Main RFs for postprocedural AIS were hypotension, prosthetic cardiac material, right-to-left shunt, arrhythmias, low cardiac output, and infections. In children with postprocedural AIS, time to diagnosis was delayed. Most patients presented multiple potentially modifiable RFs as hemodynamic alterations and infections.
Sections du résumé
BACKGROUND AND PURPOSE
Cardiac pathologies are the second most frequent risk factor (RF) in children with arterial ischemic stroke (AIS). This study aimed to analyze RFs for AIS in children with cardiac disease and cardiac intervention.
METHODS
Data were drawn from the Swiss Neuropediatric Stroke Registry. Patients with cardiac disease and postprocedural AIS registered from 2000 until 2015 were analyzed for the cause of cardiac disease and for potential RFs.
RESULTS
Forty-seven out of 78 children with cardiac disease had a cardiac intervention. Of these, 36 presented a postprocedural AIS. Median time from cardiac intervention to symptom onset was 4 days (interquartile range, 2-8.5); time to diagnosis of AIS was 2 days (interquartile range, 0-5.8). Main RFs for postprocedural AIS were hypotension, prosthetic cardiac material, right-to-left shunt, arrhythmias, low cardiac output, and infections.
CONCLUSIONS
In children with postprocedural AIS, time to diagnosis was delayed. Most patients presented multiple potentially modifiable RFs as hemodynamic alterations and infections.
Identifiants
pubmed: 32811375
doi: 10.1161/STROKEAHA.120.029447
doi:
Types de publication
Journal Article
Multicenter Study
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM