The metabolic effects of mirabegron are mediated primarily by β

Acetanilides / administration & dosage Adenosine Monophosphate / metabolism Adipocytes, Beige / drug effects Adipocytes, Brown / drug effects Adrenergic beta-3 Receptor Agonists / administration & dosage Animals CHO Cells Cells, Cultured Cricetulus Deoxyglucose / metabolism Gene Knockout Techniques Glycolysis / drug effects Male Mice Oxygen / metabolism Thiazoles / administration & dosage Uncoupling Protein 1 / genetics
UCP1 adipocyte glucose mirabegron β3-adrenoceptor

Journal

Pharmacology research & perspectives
ISSN: 2052-1707
Titre abrégé: Pharmacol Res Perspect
Pays: United States
ID NLM: 101626369

Informations de publication

Date de publication:
10 2020
Historique:
received: 16 06 2020
revised: 16 07 2020
accepted: 19 07 2020
entrez: 20 8 2020
pubmed: 20 8 2020
medline: 30 6 2021
Statut: ppublish

Résumé

The β

Identifiants

DOI: 10.1002/prp2.643 PMID: 32813332 PMC: PMC7437350
pubmed: 32813332
doi: 10.1002/prp2.643
pmc: PMC7437350
doi:

Substances chimiques

Acetanilides 0
Adrenergic beta-3 Receptor Agonists 0
Thiazoles 0
Ucp1 protein, mouse 0
Uncoupling Protein 1 0
Adenosine Monophosphate 415SHH325A
Deoxyglucose 9G2MP84A8W
mirabegron MVR3JL3B2V
Oxygen S88TT14065

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

e00643

Informations de copyright

© 2020 The Authors. Pharmacology Research & Perspectives published by British Pharmacological Society and American Society for Pharmacology and Experimental Therapeutics and John Wiley & Sons Ltd.

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Auteurs

Nodi Dehvari (N)

Department of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University, Stockholm, Sweden.

Masaaki Sato (M)

Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Vic., Australia.

Muhammad Hamza Bokhari (MH)

Department of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University, Stockholm, Sweden.
ORCID: 0000-0001-6459-8679

Anastasia Kalinovich (A)

Department of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University, Stockholm, Sweden.

Seungmin Ham (S)

Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Vic., Australia.

Jie Gao (J)

Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Vic., Australia.

Huong T M Nguyen (HTM)

Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Vic., Australia.

Lynda Whiting (L)

Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Vic., Australia.

Saori Mukaida (S)

Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Vic., Australia.

Jon Merlin (J)

Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Vic., Australia.

Ling Yeong Chia (LY)

Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Vic., Australia.

Denise Wootten (D)

Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Vic., Australia.

Roger J Summers (RJ)

Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Vic., Australia.

Bronwyn A Evans (BA)

Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Vic., Australia.

Tore Bengtsson (T)

Department of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University, Stockholm, Sweden.

Dana S Hutchinson (DS)

Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Vic., Australia.
ORCID: 0000-0001-9947-0106

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Classifications MeSH

questionsmedicales.fr › Composés chimiques organiques › Amines › Dérivés de l'aniline › Anilides › Acétanilides › The metabolic effects of mirabegron are...
questionsmedicales.fr › Acides nucléiques, nucléotides et nucléosides › Nucléotides › Ribonucléotides › Nucléotides adényliques › AMP › The metabolic effects of mirabegron are...
questionsmedicales.fr › Cellules › Cellules du tissu conjonctif › Adipocytes › Adipocytes beiges › The metabolic effects of mirabegron are...
questionsmedicales.fr › Cellules › Cellules du tissu conjonctif › Adipocytes › Adipocytes bruns › The metabolic effects of mirabegron are...
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Effets physiologiques des médicaments › Agents neuromédiateurs › Agents adrénergiques › Agonistes adrénergiques › Agonistes bêta-adrénergiques › Agonistes des récepteurs bêta-3 adrénergiques › The metabolic effects of mirabegron are...
questionsmedicales.fr › Eucaryotes › Animaux › The metabolic effects of mirabegron are...
questionsmedicales.fr › Cellules › Cellules épithéliales › Cellules CHO › The metabolic effects of mirabegron are...
questionsmedicales.fr › Cellules › Cellules cultivées › The metabolic effects of mirabegron are...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Arvicolinae › Cricetinae › Cricetulus › The metabolic effects of mirabegron are...
questionsmedicales.fr › Glucides › Désoses › Désoxyglucose › The metabolic effects of mirabegron are...
questionsmedicales.fr › Techniques d'investigation › Techniques génétiques › Ciblage de gène › Techniques de knock-out de gènes › The metabolic effects of mirabegron are...
questionsmedicales.fr › Métabolisme › Voies et réseaux métaboliques › Glycolyse › The metabolic effects of mirabegron are...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › The metabolic effects of mirabegron are...
questionsmedicales.fr › Produits chimiques inorganiques › Gaz › Oxygène › The metabolic effects of mirabegron are...
questionsmedicales.fr › Composés hétérocycliques › Composés hétéromonocycliques › Azoles › Thiazoles › The metabolic effects of mirabegron are...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines mitochondriales › Protéines de transport de la membrane mitochondriale › Protéines de découplage mitochondrial › Protéine-1 de découplage › The metabolic effects of mirabegron are...