Exercise-induced ventricular tachycardia in a case with hypertrophic cardiomyopathy taking cibenzoline.
Adolescent
Anti-Arrhythmia Agents
/ therapeutic use
Cardiomyopathy, Hypertrophic
/ complications
Cardiopulmonary Resuscitation
/ methods
Exercise
Exercise Test
/ adverse effects
Female
Humans
Imidazoles
/ therapeutic use
Sotalol
/ therapeutic use
Tachycardia, Ventricular
/ complications
Ventricular Fibrillation
/ complications
QRS duration
hypertrophic cardiomyopathy
proarrhythmia
sodium channel blocker
use-dependent
ventricular tachycardia
Journal
Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc
ISSN: 1542-474X
Titre abrégé: Ann Noninvasive Electrocardiol
Pays: United States
ID NLM: 9607443
Informations de publication
Date de publication:
01 2021
01 2021
Historique:
received:
01
05
2020
revised:
15
05
2020
accepted:
24
06
2020
pubmed:
20
8
2020
medline:
26
10
2021
entrez:
20
8
2020
Statut:
ppublish
Résumé
We report a 17-year-old woman with hypertrophic cardiomyopathy (HCM) successfully resuscitated from ventricular fibrillation while taking cibenzoline. During exercise-stress testing before implanting an implantable cardioverter-defibrillator, ventricular tachycardia was induced and thought to be a proarrhythmia due to the use-dependent effect of the Na channel blockade with cibenzoline. In patients with arrhythmogenic substrates such as HCM, it is critical to pay attention to the proarrhythmic effects of class I antiarrhythmic drugs while increasing heart rate.
Identifiants
pubmed: 32813916
doi: 10.1111/anec.12789
pmc: PMC7816811
doi:
Substances chimiques
Anti-Arrhythmia Agents
0
Imidazoles
0
Sotalol
A6D97U294I
cifenline
Z7489237QT
Types de publication
Case Reports
Langues
eng
Sous-ensembles de citation
IM
Pagination
e12789Informations de copyright
© 2020 The Authors. Annals of Noninvasive Electrocardiology published by Wiley Periodicals LLC.
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