Characteristics and causes of death in children with neonatal abstinence syndrome.
childhood mortality
linkage
neonatal abstinence syndrome
Journal
Journal of paediatrics and child health
ISSN: 1440-1754
Titre abrégé: J Paediatr Child Health
Pays: Australia
ID NLM: 9005421
Informations de publication
Date de publication:
Dec 2020
Dec 2020
Historique:
received:
16
04
2020
revised:
21
06
2020
accepted:
06
07
2020
pubmed:
21
8
2020
medline:
15
5
2021
entrez:
21
8
2020
Statut:
ppublish
Résumé
To determine characteristics of death in children with neonatal abstinence syndrome (NAS). A population-based linkage study of children from birth to 13 years of age in New South Wales (NSW), Australia, born 1 July 2000 to 31 December 2011. Infants with an International Statistical Classification of Diseases and Related Problems, Australian modification coding of NAS (P96.1, n = 3842) were compared to infants (n = 1 018 421) without NAS by birth, hospitalisation and death records linkage. Forty-five (1.2%) children with NAS died, compared to 3665 (0.4%) other children. Most deaths (n = 30, 66%) in NAS children occurred between 1 month and 1 year. Risk of death was independently increased in full-term children (hazard ratio 2.34, 95% confidence interval 1.63-3.35; P < 0.001) from lower socio-economic groups (1.23, 1.12-1.35; P < 0.001), most commonly from ill-defined or external causes, including assault and accidents (P < 0.001). Children with NAS, especially those of term gestation and from lower socio-economic groups, are more likely to die, especially from external causes.
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
1933-1940Informations de copyright
© 2020 Paediatrics and Child Health Division (The Royal Australasian College of Physicians).
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