On the Stability and Conformational Dynamics of Cytochrome
Journal
The journal of physical chemistry. B
ISSN: 1520-5207
Titre abrégé: J Phys Chem B
Pays: United States
ID NLM: 101157530
Informations de publication
Date de publication:
17 09 2020
17 09 2020
Historique:
pubmed:
25
8
2020
medline:
15
5
2021
entrez:
25
8
2020
Statut:
ppublish
Résumé
Owing to their potential applications in the extraction, purification, and preservation of biomolecules and biocatalysis, ionic liquids (ILs) have gained great attention in biotechnology. Although it is known that the structure and dynamics of proteins in ILs depend on the nature of both proteins and ILs, the biophysical mechanism governing the protein-IL interaction, which determines the stability of proteins or the activity of an enzyme in these nonconventional media, is yet to be understood clearly. Herein, we study the effect of two ammonium ILs, triethylammonium dihydrogen phosphate (TEAP) and tributylammonium dihydrogen phosphate (TBAP), on the stability and conformational dynamics of cytochrome
Identifiants
pubmed: 32830967
doi: 10.1021/acs.jpcb.0c05633
doi:
Substances chimiques
Ammonium Compounds
0
Ionic Liquids
0
Cytochromes c
9007-43-6
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM