On the Stability and Conformational Dynamics of Cytochrome


Journal

The journal of physical chemistry. B
ISSN: 1520-5207
Titre abrégé: J Phys Chem B
Pays: United States
ID NLM: 101157530

Informations de publication

Date de publication:
17 09 2020
Historique:
pubmed: 25 8 2020
medline: 15 5 2021
entrez: 25 8 2020
Statut: ppublish

Résumé

Owing to their potential applications in the extraction, purification, and preservation of biomolecules and biocatalysis, ionic liquids (ILs) have gained great attention in biotechnology. Although it is known that the structure and dynamics of proteins in ILs depend on the nature of both proteins and ILs, the biophysical mechanism governing the protein-IL interaction, which determines the stability of proteins or the activity of an enzyme in these nonconventional media, is yet to be understood clearly. Herein, we study the effect of two ammonium ILs, triethylammonium dihydrogen phosphate (TEAP) and tributylammonium dihydrogen phosphate (TBAP), on the stability and conformational dynamics of cytochrome

Identifiants

pubmed: 32830967
doi: 10.1021/acs.jpcb.0c05633
doi:

Substances chimiques

Ammonium Compounds 0
Ionic Liquids 0
Cytochromes c 9007-43-6

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

8132-8140

Auteurs

Ashok Pabbathi (A)

School of Chemistry, University of Hyderabad, Hyderabad 500046, India.

Anunay Samanta (A)

School of Chemistry, University of Hyderabad, Hyderabad 500046, India.

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Classifications MeSH