Hindbrain Double-Negative Feedback Mediates Palatability-Guided Food and Water Consumption.
Animals
Appetite
/ physiology
Appetite Regulation
/ physiology
Behavior Rating Scale
Drinking
/ physiology
Eating
/ physiology
Feedback
Feeding Behavior
/ physiology
Female
Glutamine
/ metabolism
Homeostasis
/ physiology
Hunger
/ physiology
Locus Coeruleus
/ cytology
Male
Mice
Mice, Knockout
Motivation
/ physiology
Nerve Net
/ physiology
Neurons
/ drug effects
Recombinant Proteins
Reward
Rhombencephalon
/ cytology
Single-Cell Analysis
/ methods
Taste
/ physiology
Thirst
/ physiology
GRIN lens
appetite
hunger
in vivo calcium imaging
ingestive behavior
locus ceruleus
locus coeruleus
palatability
periLC
thirst
Journal
Cell
ISSN: 1097-4172
Titre abrégé: Cell
Pays: United States
ID NLM: 0413066
Informations de publication
Date de publication:
17 09 2020
17 09 2020
Historique:
received:
01
11
2019
revised:
12
05
2020
accepted:
21
07
2020
pubmed:
26
8
2020
medline:
20
5
2021
entrez:
26
8
2020
Statut:
ppublish
Résumé
Hunger and thirst have distinct goals but control similar ingestive behaviors, and little is known about neural processes that are shared between these behavioral states. We identify glutamatergic neurons in the peri-locus coeruleus (periLC
Identifiants
pubmed: 32841600
pii: S0092-8674(20)30939-9
doi: 10.1016/j.cell.2020.07.031
pii:
doi:
Substances chimiques
Recombinant Proteins
0
Glutamine
0RH81L854J
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
1589-1605.e22Subventions
Organisme : Howard Hughes Medical Institute
Pays : United States
Commentaires et corrections
Type : CommentIn
Informations de copyright
Copyright © 2020 Elsevier Inc. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of Interests S.M.S. has served on the Scientific Advisory Board of Inscopix, Inc. and owns stock in the company.