Biotransformation of two citrus flavanones by lactic acid bacteria in chemical defined medium.
Biological activity
Biotransformation
Citrus flavanones
Lactic acid bacteria
Metabolites
Journal
Bioprocess and biosystems engineering
ISSN: 1615-7605
Titre abrégé: Bioprocess Biosyst Eng
Pays: Germany
ID NLM: 101088505
Informations de publication
Date de publication:
Feb 2021
Feb 2021
Historique:
received:
23
08
2019
accepted:
26
08
2020
pubmed:
6
9
2020
medline:
28
10
2021
entrez:
5
9
2020
Statut:
ppublish
Résumé
Microbial processes are being developed to transform flavonoid glycosides to varieties of metabolites with higher bioavailability. The aim of this study was to determine the metabolic activity and survival of five lactic acid bacteria (LAB) stains (L. rhamnosus LRa05, L. casei LC89, L. plantarum N13, L. acidophilus LA85, and L. brevis LB01) in two different citrus flavanone standards (hesperetin-7-O-rutinoside and naringenin-7-O-rutinoside). The enzymatic activity, metabolites, antioxidant activities, and α-glucosidase inhibition property in the two standards were also investigated before and after incubated with LAB. The medium contained standards permitted survival of the five LAB stains. All strains exhibited β-glucosidase activity. Of the five LAB strains tested, just L. plantarum N13 and L. brevis LB01 have the ability to metabolize hesperetin-7-O-rutinoside, only L. plantarum N13, L. acidophilus LA85, and L. brevis LB01 could metabolize naringenin-7-O-rutinoside, moreover, L. acidophilus LA85l was the strain with the highest biotransformation ratio of naringenin-7-O-rutinoside. L. acidophilus LA85 and L. plantarum N13 can degrade naringenin-7-O-rutinoside into naringenin. L. brevis LB01 can degrade hesperetin-7-O-rutinoside into hesperetin, 3-(4'-hydroxyphenyl)-2-propenoic acid, 3-(3'-hydroxy-4'-methoxyphenyl)hydracrylic acid, and 3-(4'-hydroxyphenyl)propionic acid. Incubation of L. acidophilus LA85 in naringenin-7-O-rutinoside solution supposed no apparent influence in the biological activities that tested. L. acidophilus LA85 may potentially contribute to the bioavailability of citrus flavanones, and to be applied as functional cultures to obtain more bioavailable and bioactive metabolites in food products or in the human gastrointestinal tract.
Identifiants
pubmed: 32888093
doi: 10.1007/s00449-020-02437-y
pii: 10.1007/s00449-020-02437-y
doi:
Substances chimiques
Flavanones
0
Glucosides
0
naringenin-7-O-glucoside
0
Hesperidin
E750O06Y6O
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
235-246Subventions
Organisme : Fundamental Research Funds for the National Natural Science Foundation of China
ID : 31771947
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