Regulation of Melanocortin-4 Receptor Pharmacology by Two Isoforms of Melanocortin Receptor Accessory Protein 2 in Topmouth Culter (

Adaptor Proteins, Signal Transducing / pharmacology Animals Cyclic AMP / metabolism Cyprinidae Fish Proteins / genetics Gene Expression Regulation Protein Isoforms Receptor, Melanocortin, Type 4 / genetics
constitutive activity melanocortin receptor accessory protein 2 melanocortin-4 receptor signaling topmouth culter

Journal

Frontiers in endocrinology
ISSN: 1664-2392
Titre abrégé: Front Endocrinol (Lausanne)
Pays: Switzerland
ID NLM: 101555782

Informations de publication

Date de publication:
2020
Historique:
received: 14 05 2020
accepted: 02 07 2020
entrez: 14 9 2020
pubmed: 15 9 2020
medline: 4 6 2021
Statut: epublish

Résumé

Melanocortin-4 receptor (MC4R) plays important roles in regulation of multiple physiological processes, and interaction of MC4R and melanocortin receptor accessory protein 2 (MRAP2) is suggested to play pivotal role in energy balance of vertebrates. Topmouth culter (

Identifiants

DOI: 10.3389/fendo.2020.00538 PMID: 32922362 PMC: PMC7456811
pubmed: 32922362
doi: 10.3389/fendo.2020.00538
pmc: PMC7456811
doi:

Substances chimiques

Adaptor Proteins, Signal Transducing 0
Fish Proteins 0
Protein Isoforms 0
Receptor, Melanocortin, Type 4 0
Cyclic AMP E0399OZS9N

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

538

Informations de copyright

Copyright © 2020 Tao, Ji, Huang, Fan, Liu, Liu and Tao.

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Auteurs

Min Tao (M)

State Key Laboratory of Developmental Biology of Freshwater Fish, College of Life Sciences, Hunan Normal University, Changsha, China.
Department of Anatomy, Physiology and Pharmacology, College of Veterinary Medicine, Auburn University, Auburn, AL, United States.

Ren-Lei Ji (RL)

Department of Anatomy, Physiology and Pharmacology, College of Veterinary Medicine, Auburn University, Auburn, AL, United States.

Lu Huang (L)

State Key Laboratory of Developmental Biology of Freshwater Fish, College of Life Sciences, Hunan Normal University, Changsha, China.

Si-Yu Fan (SY)

State Key Laboratory of Developmental Biology of Freshwater Fish, College of Life Sciences, Hunan Normal University, Changsha, China.

Ting Liu (T)

Department of Anatomy, Physiology and Pharmacology, College of Veterinary Medicine, Auburn University, Auburn, AL, United States.

Shao-Jun Liu (SJ)

State Key Laboratory of Developmental Biology of Freshwater Fish, College of Life Sciences, Hunan Normal University, Changsha, China.

Ya-Xiong Tao (YX)

Department of Anatomy, Physiology and Pharmacology, College of Veterinary Medicine, Auburn University, Auburn, AL, United States.

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Classifications MeSH

questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines et peptides de signalisation intracellulaire › Protéines adaptatrices de la transduction du signal › Regulation of Melanocortin-4 Receptor...
questionsmedicales.fr › Eucaryotes › Animaux › Regulation of Melanocortin-4 Receptor...
questionsmedicales.fr › Acides nucléiques, nucléotides et nucléosides › Nucléotides › Ribonucléotides › Nucléotides adényliques › AMP cyclique › Regulation of Melanocortin-4 Receptor...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Poissons › Cypriniformes › Cyprinidae › Regulation of Melanocortin-4 Receptor...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines de poisson › Regulation of Melanocortin-4 Receptor...
questionsmedicales.fr › Phénomènes génétiques › Régulation de l'expression des gènes › Regulation of Melanocortin-4 Receptor...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Isoformes de protéines › Regulation of Melanocortin-4 Receptor...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Récepteurs de surface cellulaire › Récepteurs peptidiques › Récepteur hormone hypophysaire › Récepteur corticotrophine › Récepteurs à la mélanocortine › Récepteur de la mélanocortine de type 4 › Regulation of Melanocortin-4 Receptor...