Use of DPP4 inhibitors in Italy does not correlate with diabetes prevalence among COVID-19 deaths.
COVID-19
Coronavirus
DPP4
DPP4 inhibitors
Diabetes
Dipeptidyl peptidase 4
SARS-CoV-2
Journal
Diabetes research and clinical practice
ISSN: 1872-8227
Titre abrégé: Diabetes Res Clin Pract
Pays: Ireland
ID NLM: 8508335
Informations de publication
Date de publication:
Jan 2021
Jan 2021
Historique:
received:
24
07
2020
revised:
22
08
2020
accepted:
04
09
2020
pubmed:
19
9
2020
medline:
16
2
2021
entrez:
18
9
2020
Statut:
ppublish
Résumé
In a nationwide study of 3818 charts from patients with fatal COVID-19, we found that geographical differences in Dipeptidyl peptidase 4 (DPP4) inhibitors use did not correlate with diabetes prevalence among COVID-19 deaths, thus not supporting the hypothesis of a clinically relevant involvement of DPP4 inhibition in COVID-19 development and progression.
Identifiants
pubmed: 32946854
pii: S0168-8227(20)30697-5
doi: 10.1016/j.diabres.2020.108444
pmc: PMC7492144
pii:
doi:
Substances chimiques
Dipeptidyl-Peptidase IV Inhibitors
0
DPP4 protein, human
EC 3.4.14.5
Dipeptidyl Peptidase 4
EC 3.4.14.5
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
108444Informations de copyright
Copyright © 2020 Elsevier B.V. All rights reserved.
Déclaration de conflit d'intérêts
Conflict of interests RS, MD and CP have no conflict of interest to declare for the preparation of this manuscript. EM has received speaker fees from Astra-Zeneca and Lilly and research grants from scientific societies with the unrestricted support from AstraZeneca. PP has received speaker fees from AstraZeneca, MSD and Lilly. RB has received speaker fees from AstraZeneca, MSD and Lilly
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