Pullulan derivative with cationic and hydrophobic moieties as an appropriate macromolecule in the synthesis of nanoparticles for drug delivery.
Cations
Cells, Cultured
Diclofenac
/ administration & dosage
Drug Carriers
Drug Evaluation, Preclinical
Drug Liberation
Fibroblasts
/ drug effects
Glucans
/ administration & dosage
Humans
Hydrogen-Ion Concentration
Hydrophobic and Hydrophilic Interactions
Molecular Structure
Nanoparticles
/ administration & dosage
Nuclear Magnetic Resonance, Biomolecular
Spectroscopy, Fourier Transform Infrared
Surface-Active Agents
/ administration & dosage
Viscosity
Water
Amphiphilic cationic polymer
Diclofenac
Drug release
Nanoparticles
Pullulan
Journal
International journal of biological macromolecules
ISSN: 1879-0003
Titre abrégé: Int J Biol Macromol
Pays: Netherlands
ID NLM: 7909578
Informations de publication
Date de publication:
01 Dec 2020
01 Dec 2020
Historique:
received:
25
06
2020
revised:
28
08
2020
accepted:
10
09
2020
pubmed:
19
9
2020
medline:
7
4
2021
entrez:
18
9
2020
Statut:
ppublish
Résumé
A new amphiphilic pullulan derivative (DBAP-PO) was obtained by grafting tertiary butyl amine and octanoyl groups on the pullulan backbone as cationic and hydrophobic moieties, respectively. The structural characteristics of the modified polymer were investigated by FT-IR and
Identifiants
pubmed: 32946935
pii: S0141-8130(20)34424-X
doi: 10.1016/j.ijbiomac.2020.09.064
pii:
doi:
Substances chimiques
Cations
0
Drug Carriers
0
Glucans
0
Surface-Active Agents
0
Water
059QF0KO0R
Diclofenac
144O8QL0L1
pullulan
8ZQ0AYU1TT
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
4487-4498Informations de copyright
Copyright © 2018. Published by Elsevier B.V.
Déclaration de conflit d'intérêts
Declaration of competing interest None.