Charged pore-lining residues are required for normal channel kinetics in the eukaryotic mechanosensitive ion channel MSL1.


Journal

Channels (Austin, Tex.)
ISSN: 1933-6969
Titre abrégé: Channels (Austin)
Pays: United States
ID NLM: 101321614

Informations de publication

Date de publication:
12 2020
Historique:
entrez: 29 9 2020
pubmed: 30 9 2020
medline: 17 7 2021
Statut: ppublish

Résumé

Mechanosensitive (MS) ion channels are widespread mechanisms for cellular mechanosensation that can be directly activated by increasing membrane tension. The well-studied MscS family of MS ion channels is found in bacteria, archaea, and plants. MscS-Like (MSL)1 is localized to the inner mitochondrial membrane of

Identifiants

pubmed: 32988273
doi: 10.1080/19336950.2020.1818509
pmc: PMC7757850
doi:

Substances chimiques

AT4G00290 protein, Arabidopsis 0
Arabidopsis Proteins 0
Ion Channels 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

310-325

Subventions

Organisme : Howard Hughes Medical Institute
Pays : United States

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Auteurs

Angela M Schlegel (AM)

Department of Biology, Washington University , St. Louis, Missouri, USA.
NSF Center for Engineering Mechanobiology, Washington University , St. Louis, Missouri, USA.

Elizabeth S Haswell (ES)

Department of Biology, Washington University , St. Louis, Missouri, USA.
NSF Center for Engineering Mechanobiology, Washington University , St. Louis, Missouri, USA.

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Classifications MeSH