Solution structure and RNA-binding of a minimal ProQ-homolog from

Bacterial Proteins / chemistry Legionella pneumophila / genetics Nuclear Magnetic Resonance, Biomolecular / methods Protein Binding Protein Domains RNA, Bacterial / chemistry RNA-Binding Proteins / chemistry Structure-Activity Relationship
Legionella NMR structure ProQ RNA-binding protein sRNA

Journal

RNA (New York, N.Y.)
ISSN: 1469-9001
Titre abrégé: RNA
Pays: United States
ID NLM: 9509184

Informations de publication

Date de publication:
12 2020
Historique:
received: 21 07 2020
accepted: 23 09 2020
pubmed: 30 9 2020
medline: 26 1 2021
entrez: 29 9 2020
Statut: ppublish

Résumé

Small regulatory RNAs (sRNAs) play an important role for posttranscriptional gene regulation in bacteria. sRNAs recognize their target messenger RNAs (mRNAs) by base-pairing, which is often facilitated by interactions with the bacterial RNA-binding proteins Hfq or ProQ. The FinO/ProQ RNA-binding protein domain was first discovered in the bacterial repressor of conjugation, FinO. Since then, the functional role of FinO/ProQ-like proteins in posttranscriptional gene regulation was extensively studied in particular in the enterobacteria

Identifiants

DOI: 10.1261/rna.077354.120 PMID: 32989045 PMC: PMC7668265
pubmed: 32989045
pii: rna.077354.120
doi: 10.1261/rna.077354.120
pmc: PMC7668265
doi:

Substances chimiques

Bacterial Proteins 0
RNA, Bacterial 0
RNA-Binding Proteins 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

2031-2043

Informations de copyright

© 2020 Immer et al.; Published by Cold Spring Harbor Laboratory Press for the RNA Society.

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Auteurs

Carina Immer (C)

Institute of Molecular Biosciences and Center for Biomolecular Magnetic Resonance (BMRZ), Johann-Wolfgang-Goethe-University, Frankfurt 60438, Germany.

Carolin Hacker (C)

Institute of Molecular Biosciences and Center for Biomolecular Magnetic Resonance (BMRZ), Johann-Wolfgang-Goethe-University, Frankfurt 60438, Germany.

Jens Wöhnert (J)

Institute of Molecular Biosciences and Center for Biomolecular Magnetic Resonance (BMRZ), Johann-Wolfgang-Goethe-University, Frankfurt 60438, Germany.
ORCID: 0000-0001-7193-401X

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Classifications MeSH

questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines bactériennes › Solution structure and RNA-binding of a...
questionsmedicales.fr › Bactéries › Proteobacteria › Gammaproteobacteria › Legionellaceae › Legionella › Legionella pneumophila › Solution structure and RNA-binding of a...
questionsmedicales.fr › Techniques d'investigation › Techniques de chimie analytique › Analyse spectrale › Spectroscopie par résonance magnétique › Résonance magnétique nucléaire biomoléculaire › Solution structure and RNA-binding of a...
questionsmedicales.fr › Métabolisme › Liaison aux protéines › Solution structure and RNA-binding of a...
questionsmedicales.fr › Phénomènes chimiques › Phénomènes biochimiques › Conformation moléculaire › Conformation des protéines › Structure tertiaire des protéines › Domaines protéiques › Solution structure and RNA-binding of a...
questionsmedicales.fr › Acides nucléiques, nucléotides et nucléosides › Acides nucléiques › ARN › ARN bactérien › Solution structure and RNA-binding of a...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Nucléoprotéines › Protéines de liaison à l'ARN › Solution structure and RNA-binding of a...
questionsmedicales.fr › Phénomènes physiologiques › Phénomènes pharmacologiques et toxicologiques › Phénomènes pharmacologiques › Relation structure-activité › Solution structure and RNA-binding of a...