Recent genome duplications facilitate the phenotypic diversity of Hb repertoire in the Cyprinidae.
gene duplication
gene family evolution
genome duplication
genomic organization
hemoglobin gene family
Journal
Science China. Life sciences
ISSN: 1869-1889
Titre abrégé: Sci China Life Sci
Pays: China
ID NLM: 101529880
Informations de publication
Date de publication:
Jul 2021
Jul 2021
Historique:
received:
29
05
2020
accepted:
28
08
2020
pubmed:
15
10
2020
medline:
6
1
2022
entrez:
14
10
2020
Statut:
ppublish
Résumé
Whole-genome duplications (WGDs) are an important contributor to phenotypic innovations in evolutionary history. The diversity of blood oxygen transport traits is the perfect reflection of physiological versatility for evolutionary success among vertebrates. In this study, the evolutionary changes of hemoglobin (Hb) repertoire driven by the recent genome duplications were detected in representative Cyprinidae fish, including eight diploid and four tetraploid species. Comparative genomic analysis revealed a substantial variation in both membership composition and intragenomic organization of Hb genes in these species. Phylogenetic reconstruction analyses were conducted to characterize the evolutionary history of these genes. Data were integrated with the expression profiles of the genes during ontogeny. Our results indicated that genome duplications facilitated the phenotypic diversity of the Hb gene family; each was associated with species-specific changes in gene content via gene loss and fusion after genome duplications. This led to repeated evolutionary transitions in the ontogenic regulation of Hb gene expression. Our results revealed that genome duplications helped to generate phenotypic changes in Cyprinidae Hb systems.
Identifiants
pubmed: 33051703
doi: 10.1007/s11427-020-1809-0
pii: 10.1007/s11427-020-1809-0
doi:
Substances chimiques
Hemoglobins
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
1149-1164Références
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