Perceptions of injectable opioid agonist treatment (iOAT) among people who regularly use opioids in Australia: findings from a cross-sectional study in three Australian cities.


Journal

Addiction (Abingdon, England)
ISSN: 1360-0443
Titre abrégé: Addiction
Pays: England
ID NLM: 9304118

Informations de publication

Date de publication:
06 2021
Historique:
revised: 03 08 2020
received: 06 05 2020
accepted: 13 10 2020
pubmed: 18 10 2020
medline: 24 9 2021
entrez: 17 10 2020
Statut: ppublish

Résumé

Not all people experiencing opioid dependence benefit from oral opioid agonist treatment. The aim of this study was to examine perceptions of (supervised) injectable opioid agonist treatment (iOAT) (described as 'an opioid similar to heroin self-injected at a clinic several times a day') among people who regularly use opioids and determine how common iOAT eligibility criteria accord with interest in iOAT. Cross-sectional survey SETTING: Sydney, Melbourne and Hobart, Australia PARTICIPANTS: A total of 344 people (63% male) who use opioids regularly and had ever injected opioids, interviewed December 2017-March 2018. The mean age of participants was 41.5 years [standard deviation (SD) = 8.5]. Primary outcome measures were interest in iOAT, factors associated with interest and the proportion of participants who would be eligible using common criteria from trials and guidelines. We examined willingness to travel for iOAT, medication preferences and perspectives on whom should receive iOAT. Overall, 53% of participants (n = 182) believed that iOAT would be a good treatment option for them. Participants who believed that iOAT was a good treatment option for them were more likely to be male [adjusted odds ratio (aOR) = 1.76, 95% confidence interval (CI) = 1.10-2.82], have used heroin in the past month (aOR = 6.03, 95% CI = 2.86-12.71), currently regularly inject opioids (aOR = 1.84, 95% CI = 1.16-2.91) and have met ICD-10 criteria for opioid dependence (aOR = 3.46, 95% CI = 1.65-7.24). Those interested in iOAT had commenced more treatment episodes (aOR =1.06, 95% CI = 1.00-1.12). Among those interested in iOAT (n = 182), 26% (n = 48) met common eligibility criteria for iOAT. Interest in injectable opioid agonist treatment does not appear to be universal among people who regularly use opioids. Among study participants who expressed interest in injectable opioid agonist treatment, most did not meet common eligibility criteria.

Sections du résumé

BACKGROUND AND AIMS
Not all people experiencing opioid dependence benefit from oral opioid agonist treatment. The aim of this study was to examine perceptions of (supervised) injectable opioid agonist treatment (iOAT) (described as 'an opioid similar to heroin self-injected at a clinic several times a day') among people who regularly use opioids and determine how common iOAT eligibility criteria accord with interest in iOAT.
DESIGN
Cross-sectional survey SETTING: Sydney, Melbourne and Hobart, Australia PARTICIPANTS: A total of 344 people (63% male) who use opioids regularly and had ever injected opioids, interviewed December 2017-March 2018. The mean age of participants was 41.5 years [standard deviation (SD) = 8.5].
MEASUREMENTS
Primary outcome measures were interest in iOAT, factors associated with interest and the proportion of participants who would be eligible using common criteria from trials and guidelines. We examined willingness to travel for iOAT, medication preferences and perspectives on whom should receive iOAT.
FINDINGS
Overall, 53% of participants (n = 182) believed that iOAT would be a good treatment option for them. Participants who believed that iOAT was a good treatment option for them were more likely to be male [adjusted odds ratio (aOR) = 1.76, 95% confidence interval (CI) = 1.10-2.82], have used heroin in the past month (aOR = 6.03, 95% CI = 2.86-12.71), currently regularly inject opioids (aOR = 1.84, 95% CI = 1.16-2.91) and have met ICD-10 criteria for opioid dependence (aOR = 3.46, 95% CI = 1.65-7.24). Those interested in iOAT had commenced more treatment episodes (aOR =1.06, 95% CI = 1.00-1.12). Among those interested in iOAT (n = 182), 26% (n = 48) met common eligibility criteria for iOAT.
CONCLUSIONS
Interest in injectable opioid agonist treatment does not appear to be universal among people who regularly use opioids. Among study participants who expressed interest in injectable opioid agonist treatment, most did not meet common eligibility criteria.

Identifiants

pubmed: 33067836
doi: 10.1111/add.15297
doi:

Substances chimiques

Analgesics, Opioid 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

1482-1494

Informations de copyright

© 2020 Society for the Study of Addiction.

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Auteurs

Suzanne Nielsen (S)

Monash Addiction Research Centre, Eastern Health Clinical School, Monash University, Melbourne, Australia.
National Drug and Alcohol Research Centre, UNSW Sydney, Sydney, Australia.

Paul Sanfilippo (P)

Monash Addiction Research Centre, Eastern Health Clinical School, Monash University, Melbourne, Australia.

Vendula Belackova (V)

Medically Supervised Injecting Centre, Sydney, Australia.
Centre for Social Research in Health, UNSW Sydney, Sydney, Australia.

Carolyn Day (C)

Medically Supervised Injecting Centre, Sydney, Australia.
Discipline of Addiction Medicine, University of Sydney, Sydney, Australia.

Ed Silins (E)

National Drug and Alcohol Research Centre, UNSW Sydney, Sydney, Australia.
Medically Supervised Injecting Centre, Sydney, Australia.

Nicholas Lintzeris (N)

Discipline of Addiction Medicine, University of Sydney, Sydney, Australia.
Drug and Alcohol Services, South Eastern Sydney Local Health District, Sydney, Australia.

Raimondo Bruno (R)

School of Medicines (Psychology), University of Tasmania, Hobart, Australia.

Jason Grebely (J)

Kirby Institute, UNSW Sydney, Sydney, Australia.

Kari Lancaster (K)

Centre for Social Research in Health, UNSW Sydney, Sydney, Australia.

Robert Ali (R)

Faculty of Health and Medical Sciences, University of Adelaide, Adelaide, Australia.

James Bell (J)

Medically Supervised Injecting Centre, Sydney, Australia.
Centre for Social Research in Health, UNSW Sydney, Sydney, Australia.

Paul Dietze (P)

Burnet Institute, Melbourne, Australia.

Louisa Degenhardt (L)

National Drug and Alcohol Research Centre, UNSW Sydney, Sydney, Australia.

Michael Farrell (M)

National Drug and Alcohol Research Centre, UNSW Sydney, Sydney, Australia.

Briony Larance (B)

National Drug and Alcohol Research Centre, UNSW Sydney, Sydney, Australia.
School of Psychology, University of Wollongong, Wollongong, Australia.

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