Excess mortality in the first COVID pandemic peak: cross-sectional analyses of the impact of age, sex, ethnicity, household size, and long-term conditions in people of known SARS-CoV-2 status in England.
Age Factors
COVID-19
/ diagnosis
Electronic Health Records
/ statistics & numerical data
England
/ epidemiology
Ethnicity
Family Characteristics
Female
Humans
Male
Middle Aged
Mortality
Noncommunicable Diseases
/ epidemiology
Risk Assessment
/ methods
Risk Factors
SARS-CoV-2
/ isolation & purification
Sentinel Surveillance
Sex Factors
medical record systems, computerized
mortality
pandemics
sentinel surveillance
severe acute respiratory syndrome coronavirus 2
Journal
The British journal of general practice : the journal of the Royal College of General Practitioners
ISSN: 1478-5242
Titre abrégé: Br J Gen Pract
Pays: England
ID NLM: 9005323
Informations de publication
Date de publication:
12 2020
12 2020
Historique:
received:
07
07
2020
accepted:
20
09
2020
pubmed:
21
10
2020
medline:
15
12
2020
entrez:
20
10
2020
Statut:
epublish
Résumé
The SARS-CoV-2 pandemic has passed its first peak in Europe. To describe the mortality in England and its association with SARS-CoV-2 status and other demographic and risk factors. Cross-sectional analyses of people with known SARS-CoV-2 status in the Oxford RCGP Research and Surveillance Centre (RSC) sentinel network. Pseudonymised, coded clinical data were uploaded from volunteer general practice members of this nationally representative network ( Mortality peaked in week 16. People living in households of ≥9 had a fivefold increase in relative mortality (RHR = 5.1, 95% CI = 4.87 to 5.31, The first SARS-CoV-2 peak in England has been associated with excess mortality. Planning for subsequent peaks needs to better manage risk in males, those of black ethnicity, older people, people with learning disabilities, and people who live in multi-occupancy dwellings.
Sections du résumé
BACKGROUND
The SARS-CoV-2 pandemic has passed its first peak in Europe.
AIM
To describe the mortality in England and its association with SARS-CoV-2 status and other demographic and risk factors.
DESIGN AND SETTING
Cross-sectional analyses of people with known SARS-CoV-2 status in the Oxford RCGP Research and Surveillance Centre (RSC) sentinel network.
METHOD
Pseudonymised, coded clinical data were uploaded from volunteer general practice members of this nationally representative network (
RESULTS
Mortality peaked in week 16. People living in households of ≥9 had a fivefold increase in relative mortality (RHR = 5.1, 95% CI = 4.87 to 5.31,
CONCLUSION
The first SARS-CoV-2 peak in England has been associated with excess mortality. Planning for subsequent peaks needs to better manage risk in males, those of black ethnicity, older people, people with learning disabilities, and people who live in multi-occupancy dwellings.
Identifiants
pubmed: 33077508
pii: bjgp20X713393
doi: 10.3399/bjgp20X713393
pmc: PMC7575407
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
e890-e898Subventions
Organisme : Wellcome Trust
ID : 211182/Z/18/Z
Pays : United Kingdom
Informations de copyright
©The Authors.
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