Draft genome of Bugula neritina, a colonial animal packing powerful symbionts and potential medicines.


Journal

Scientific data
ISSN: 2052-4463
Titre abrégé: Sci Data
Pays: England
ID NLM: 101640192

Informations de publication

Date de publication:
20 10 2020
Historique:
received: 26 02 2020
accepted: 09 09 2020
entrez: 21 10 2020
pubmed: 22 10 2020
medline: 14 1 2021
Statut: epublish

Résumé

Many animal phyla have no representatives within the catalog of whole metazoan genome sequences. This dataset fills in one gap in the genome knowledge of animal phyla with a draft genome of Bugula neritina (phylum Bryozoa). Interest in this species spans ecology and biomedical sciences because B. neritina is the natural source of bioactive compounds called bryostatins. Here we present a draft assembly of the B. neritina genome obtained from PacBio and Illumina HiSeq data, as well as genes and proteins predicted de novo and verified using transcriptome data, along with the functional annotation. These sequences will permit a better understanding of host-symbiont interactions at the genomic level, and also contribute additional phylogenomic markers to evaluate Lophophorate or Lophotrochozoa phylogenetic relationships. The effort also fits well with plans to ultimately sequence all orders of the Metazoa.

Identifiants

pubmed: 33082320
doi: 10.1038/s41597-020-00684-y
pii: 10.1038/s41597-020-00684-y
pmc: PMC7576161
doi:

Substances chimiques

Bryostatins 0

Types de publication

Dataset Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

356

Subventions

Organisme : Saint Petersburg State University (St. Petersburg State University)
ID : PURE 51555639
Pays : International
Organisme : Russian Foundation for Basic Research (RFBR)
ID : 17-00-00144
Pays : International
Organisme : Russian Foundation for Basic Research (RFBR)
ID : 17-00-00144
Pays : International

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Auteurs

Mikhail Rayko (M)

Center for Algorithmic Biotechnology, Institute of Translational Biomedicine, St. Petersburg State University, St. Petersburg, 199034, Russia.

Aleksey Komissarov (A)

Applied Genomics Laboratory, SCAMT Institute, ITMO University, Saint Petersburg, 197101, Russia.

Jason C Kwan (JC)

Division of Pharmaceutical Sciences, School of Pharmacy, University of Wisconsin-Madison, Madison, WI, 53706, USA.

Grace Lim-Fong (G)

Department of Biology, Randolph-Macon College, Ashland, VA, 23005, USA.

Adelaide C Rhodes (AC)

Zoologistics Consulting, Salem, MA, 01970, USA.

Sergey Kliver (S)

Applied Genomics Laboratory, SCAMT Institute, ITMO University, Saint Petersburg, 197101, Russia.
Institute of Molecular and Cellular Biology, Siberian Branch of the Russian Academy of Sciences, Novosibirsk, 630090, Russia.

Polina Kuchur (P)

Applied Genomics Laboratory, SCAMT Institute, ITMO University, Saint Petersburg, 197101, Russia.

Stephen J O'Brien (SJ)

Genomic Diversity Laboratory, ITMO University, Saint Petersburg, 197101, Russia.
Halmos College of Arts and Sciences, Nova Southeastern University, Ft Lauderdale, FL, 33314, USA.

Jose V Lopez (JV)

Halmos College of Arts and Sciences, Nova Southeastern University, Ft Lauderdale, FL, 33314, USA. joslo@nova.edu.

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Classifications MeSH