Adrenergic Ca

Adrenergic beta-Agonists / pharmacology Animals Calcium Channels, L-Type / genetics HEK293 Cells Heart Failure / genetics Humans Ion Channel Gating / drug effects Membrane Potentials Mice, Transgenic Mutation Myocytes, Cardiac / drug effects Phosphorylation Protein Conformation Rabbits Structure-Activity Relationship ras Proteins / genetics
calcium calcium channels cyclic AMP-dependent protein kinases ion channels physiology

Journal

Circulation research
ISSN: 1524-4571
Titre abrégé: Circ Res
Pays: United States
ID NLM: 0047103

Informations de publication

Date de publication:
08 01 2021
Historique:
pubmed: 23 10 2020
medline: 27 7 2021
entrez: 22 10 2020
Statut: ppublish

Résumé

Changing activity of cardiac Ca The primary goal of this study was to determine how various factors converging at the Ca We generated transgenic mice with expression of Ca Ca

Identifiants

DOI: 10.1161/CIRCRESAHA.120.317839 PMID: 33086983 PMC: PMC7790865
pubmed: 33086983
doi: 10.1161/CIRCRESAHA.120.317839
pmc: PMC7790865
mid: NIHMS1640699
doi:

Substances chimiques

Adrenergic beta-Agonists 0
CACNA1C protein, human 0
Calcium Channels, L-Type 0
Rrad protein, mouse 0
ras Proteins EC 3.6.5.2

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S.

Langues

eng

Sous-ensembles de citation

IM

Pagination

76-88

Subventions

Organisme : NCRR NIH HHS
ID : S10 RR027050
Pays : United States
Organisme : NHLBI NIH HHS
ID : T32 HL120826
Pays : United States
Organisme : NHLBI NIH HHS
ID : R01 HL126735
Pays : United States
Organisme : NHLBI NIH HHS
ID : R01 HL146149
Pays : United States
Organisme : NCI NIH HHS
ID : P30 CA013696
Pays : United States
Organisme : NHLBI NIH HHS
ID : T32 HL007343
Pays : United States
Organisme : NHLBI NIH HHS
ID : R01 HL121253
Pays : United States
Organisme : NHLBI NIH HHS
ID : T32 HL007854
Pays : United States
Organisme : NHLBI NIH HHS
ID : R01 HL140934
Pays : United States

Commentaires et corrections

Type : CommentIn

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Auteurs

Arianne Papa (A)

Division of Cardiology, Department of Medicine (A.P., J.K., J.A.H., A.N.K., S.I.Z., B.-x.C., L.Y., R.L., S.L., G.L., D.R., X.L., V.T., S.O.M.), Columbia University, Vagelos College of Physicians and Surgeons, New York, NY.
Department of Physiology and Cellular Biophysics (A.P., J.D., P.J.d.R.M., H.M.C., O.C., M.B.-J.), Columbia University, Vagelos College of Physicians and Surgeons, New York, NY.

Jared Kushner (J)

Division of Cardiology, Department of Medicine (A.P., J.K., J.A.H., A.N.K., S.I.Z., B.-x.C., L.Y., R.L., S.L., G.L., D.R., X.L., V.T., S.O.M.), Columbia University, Vagelos College of Physicians and Surgeons, New York, NY.

Jessica A Hennessey (JA)

Division of Cardiology, Department of Medicine (A.P., J.K., J.A.H., A.N.K., S.I.Z., B.-x.C., L.Y., R.L., S.L., G.L., D.R., X.L., V.T., S.O.M.), Columbia University, Vagelos College of Physicians and Surgeons, New York, NY.

Alexander N Katchman (AN)

Division of Cardiology, Department of Medicine (A.P., J.K., J.A.H., A.N.K., S.I.Z., B.-x.C., L.Y., R.L., S.L., G.L., D.R., X.L., V.T., S.O.M.), Columbia University, Vagelos College of Physicians and Surgeons, New York, NY.

Sergey I Zakharov (SI)

Division of Cardiology, Department of Medicine (A.P., J.K., J.A.H., A.N.K., S.I.Z., B.-x.C., L.Y., R.L., S.L., G.L., D.R., X.L., V.T., S.O.M.), Columbia University, Vagelos College of Physicians and Surgeons, New York, NY.

Bi-Xing Chen (BX)

Division of Cardiology, Department of Medicine (A.P., J.K., J.A.H., A.N.K., S.I.Z., B.-x.C., L.Y., R.L., S.L., G.L., D.R., X.L., V.T., S.O.M.), Columbia University, Vagelos College of Physicians and Surgeons, New York, NY.

Lin Yang (L)

Division of Cardiology, Department of Medicine (A.P., J.K., J.A.H., A.N.K., S.I.Z., B.-x.C., L.Y., R.L., S.L., G.L., D.R., X.L., V.T., S.O.M.), Columbia University, Vagelos College of Physicians and Surgeons, New York, NY.

Ree Lu (R)

Division of Cardiology, Department of Medicine (A.P., J.K., J.A.H., A.N.K., S.I.Z., B.-x.C., L.Y., R.L., S.L., G.L., D.R., X.L., V.T., S.O.M.), Columbia University, Vagelos College of Physicians and Surgeons, New York, NY.

Stephen Leong (S)

Division of Cardiology, Department of Medicine (A.P., J.K., J.A.H., A.N.K., S.I.Z., B.-x.C., L.Y., R.L., S.L., G.L., D.R., X.L., V.T., S.O.M.), Columbia University, Vagelos College of Physicians and Surgeons, New York, NY.

Johanna Diaz (J)

Department of Physiology and Cellular Biophysics (A.P., J.D., P.J.d.R.M., H.M.C., O.C., M.B.-J.), Columbia University, Vagelos College of Physicians and Surgeons, New York, NY.

Guoxia Liu (G)

Division of Cardiology, Department of Medicine (A.P., J.K., J.A.H., A.N.K., S.I.Z., B.-x.C., L.Y., R.L., S.L., G.L., D.R., X.L., V.T., S.O.M.), Columbia University, Vagelos College of Physicians and Surgeons, New York, NY.

Daniel Roybal (D)

Division of Cardiology, Department of Medicine (A.P., J.K., J.A.H., A.N.K., S.I.Z., B.-x.C., L.Y., R.L., S.L., G.L., D.R., X.L., V.T., S.O.M.), Columbia University, Vagelos College of Physicians and Surgeons, New York, NY.
Department of Pharmacology and Molecular Signaling (D.R., H.M.C., S.O.M.), Columbia University, Vagelos College of Physicians and Surgeons, New York, NY.

Xianghai Liao (X)

Division of Cardiology, Department of Medicine (A.P., J.K., J.A.H., A.N.K., S.I.Z., B.-x.C., L.Y., R.L., S.L., G.L., D.R., X.L., V.T., S.O.M.), Columbia University, Vagelos College of Physicians and Surgeons, New York, NY.

Pedro J Del Rivero Morfin (PJ)

Department of Physiology and Cellular Biophysics (A.P., J.D., P.J.d.R.M., H.M.C., O.C., M.B.-J.), Columbia University, Vagelos College of Physicians and Surgeons, New York, NY.

Henry M Colecraft (HM)

Department of Physiology and Cellular Biophysics (A.P., J.D., P.J.d.R.M., H.M.C., O.C., M.B.-J.), Columbia University, Vagelos College of Physicians and Surgeons, New York, NY.
Department of Pharmacology and Molecular Signaling (D.R., H.M.C., S.O.M.), Columbia University, Vagelos College of Physicians and Surgeons, New York, NY.

Geoffrey S Pitt (GS)

Cardiovascular Research Institute, Weill Cornell Medical College, New York, New York (G.S.P.).

Oliver Clarke (O)

Department of Physiology and Cellular Biophysics (A.P., J.D., P.J.d.R.M., H.M.C., O.C., M.B.-J.), Columbia University, Vagelos College of Physicians and Surgeons, New York, NY.

Veli Topkara (V)

Division of Cardiology, Department of Medicine (A.P., J.K., J.A.H., A.N.K., S.I.Z., B.-x.C., L.Y., R.L., S.L., G.L., D.R., X.L., V.T., S.O.M.), Columbia University, Vagelos College of Physicians and Surgeons, New York, NY.

Manu Ben-Johny (M)

Department of Physiology and Cellular Biophysics (A.P., J.D., P.J.d.R.M., H.M.C., O.C., M.B.-J.), Columbia University, Vagelos College of Physicians and Surgeons, New York, NY.

Steven O Marx (SO)

Division of Cardiology, Department of Medicine (A.P., J.K., J.A.H., A.N.K., S.I.Z., B.-x.C., L.Y., R.L., S.L., G.L., D.R., X.L., V.T., S.O.M.), Columbia University, Vagelos College of Physicians and Surgeons, New York, NY.
Department of Pharmacology and Molecular Signaling (D.R., H.M.C., S.O.M.), Columbia University, Vagelos College of Physicians and Surgeons, New York, NY.

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Classifications MeSH

questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Effets physiologiques des médicaments › Agents neuromédiateurs › Agents adrénergiques › Agonistes adrénergiques › Agonistes bêta-adrénergiques › Adrenergic Ca
questionsmedicales.fr › Eucaryotes › Animaux › Adrenergic Ca
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Protéines de transport membranaire › Canaux ioniques › Canaux calciques › Canaux calciques de type L › Adrenergic Ca
questionsmedicales.fr › Cellules › Cellules épithéliales › Cellules HEK293 › Adrenergic Ca
questionsmedicales.fr › Maladies cardiovasculaires › Cardiopathies › Défaillance cardiaque › Adrenergic Ca
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Adrenergic Ca
questionsmedicales.fr › Phénomènes physiologiques › Phénomènes électrophysiologiques › Ouverture et fermeture des portes des canaux ioniques › Adrenergic Ca
questionsmedicales.fr › Phénomènes physiologiques de l'appareil locomoteur et du système nerveux › Phénomènes physiologiques du système nerveux › Potentiels de membrane › Adrenergic Ca
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Souris transgéniques › Adrenergic Ca
questionsmedicales.fr › Phénomènes génétiques › Variation génétique › Mutation › Adrenergic Ca
questionsmedicales.fr › Cellules › Cellules musculaires › Myocytes cardiaques › Adrenergic Ca
questionsmedicales.fr › Métabolisme › Phosphorylation › Adrenergic Ca
questionsmedicales.fr › Phénomènes chimiques › Phénomènes biochimiques › Conformation moléculaire › Conformation des protéines › Adrenergic Ca
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Lagomorpha › Lapins › Adrenergic Ca
questionsmedicales.fr › Phénomènes physiologiques › Phénomènes pharmacologiques et toxicologiques › Phénomènes pharmacologiques › Relation structure-activité › Adrenergic Ca
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines et peptides de signalisation intracellulaire › Protéines G › Protéines G monomériques › Protéines G ras › Adrenergic Ca