Re-laparoscopy in the treatment of anastomotic leak following laparoscopic right colectomy with intracorporeal anastomosis.


Journal

Surgical endoscopy
ISSN: 1432-2218
Titre abrégé: Surg Endosc
Pays: Germany
ID NLM: 8806653

Informations de publication

Date de publication:
11 2021
Historique:
received: 11 05 2020
accepted: 16 10 2020
pubmed: 27 10 2020
medline: 26 10 2021
entrez: 26 10 2020
Statut: ppublish

Résumé

Anastomotic leak still represents the most feared surgical complication following colorectal resection and is associated with high morbidity and mortality rates. The aim of this study is to assess the feasibility and safety of laparoscopic reoperation for symptomatic anastomotic leak (AL) after laparoscopic right colectomy with mechanical intracorporeal anastomosis (IA). From January 2012 to December 2019, 428 consecutive laparoscopic right colectomy with IA were performed. Overall symptomatic AL rate requiring reoperation was 5.8% (26/428). Data on patient demographics as well as operative findings, time elapsed from primary surgery and from the onset of symptoms of anastomotic leak, time and duration of re-laparoscopy, ICU stay, morbidity, mortality rate, length of hospital stay and readmission, were all retrospectively reviewed. Laparoscopic approach was attempted in 23 (88.4%) hemodynamically stable patients. Conversion rate was 21.4%. Reasons for conversion were gross fecal peritonitis (n = 2), colonic ischemia (n = 1), severe bowel distension (n = 2). Eighteen (78.2%) patients underwent successfully laparoscopic (LPS) reoperation. A repair of the anastomotic defect was done in 11 (61.1%) patients, while in 7 patients the intracorporeal mechanical anastomosis was refashioned. A diverting ileostomy was done in 22.2% of cases (n = 4). A second reoperation for leak persistence was necessary in two cases (11.1%). Median (range) length of postoperative hospital stay from re-laparoscopy was 15.5 (9-53) days. Overall morbidity rate was 38.7%. Mortality rate was 5.5% (n = 1) CONCLUSION: laparoscopic re-intervention for the treatment of anastomotic leak following LPS right colectomy with intracorporeal anastomosis in hemodynamically stable and highly selected patients in the experienced hands of dedicated laparoscopic surgeons, is a safe option with acceptable morbidity and mortality rate.

Sections du résumé

BACKGROUND
Anastomotic leak still represents the most feared surgical complication following colorectal resection and is associated with high morbidity and mortality rates. The aim of this study is to assess the feasibility and safety of laparoscopic reoperation for symptomatic anastomotic leak (AL) after laparoscopic right colectomy with mechanical intracorporeal anastomosis (IA).
METHODS
From January 2012 to December 2019, 428 consecutive laparoscopic right colectomy with IA were performed. Overall symptomatic AL rate requiring reoperation was 5.8% (26/428). Data on patient demographics as well as operative findings, time elapsed from primary surgery and from the onset of symptoms of anastomotic leak, time and duration of re-laparoscopy, ICU stay, morbidity, mortality rate, length of hospital stay and readmission, were all retrospectively reviewed.
RESULTS
Laparoscopic approach was attempted in 23 (88.4%) hemodynamically stable patients. Conversion rate was 21.4%. Reasons for conversion were gross fecal peritonitis (n = 2), colonic ischemia (n = 1), severe bowel distension (n = 2). Eighteen (78.2%) patients underwent successfully laparoscopic (LPS) reoperation. A repair of the anastomotic defect was done in 11 (61.1%) patients, while in 7 patients the intracorporeal mechanical anastomosis was refashioned. A diverting ileostomy was done in 22.2% of cases (n = 4). A second reoperation for leak persistence was necessary in two cases (11.1%). Median (range) length of postoperative hospital stay from re-laparoscopy was 15.5 (9-53) days. Overall morbidity rate was 38.7%. Mortality rate was 5.5% (n = 1) CONCLUSION: laparoscopic re-intervention for the treatment of anastomotic leak following LPS right colectomy with intracorporeal anastomosis in hemodynamically stable and highly selected patients in the experienced hands of dedicated laparoscopic surgeons, is a safe option with acceptable morbidity and mortality rate.

Identifiants

pubmed: 33104916
doi: 10.1007/s00464-020-08113-2
pii: 10.1007/s00464-020-08113-2
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

6173-6178

Informations de copyright

© 2020. Springer Science+Business Media, LLC, part of Springer Nature.

Références

Soeters PB, de Zoete JP, Dejong CH, Williams NS, Baeten CG (2002) Colorectal surgery and anastomotic leakage. Dig Surg 19:150–155. https://doi.org/10.1159/0000520312
doi: 10.1159/0000520312 pubmed: 11979005
Buchs NC, Gervaz P, Secic M, Bucher P, Mugnier-Konrad B, Morel P (2008) Incidence, consequences, and risk factors for anastomotic dehiscence after colorectal surgery: a prospective monocentric study. Int J Colorectal Dis 23:265–270. https://doi.org/10.1007/s00384-007-0399-3
doi: 10.1007/s00384-007-0399-3 pubmed: 18034250
Joh YG, Kim SH, Hahn KY, Stulberg J, Chung CS, Lee DK (2009) Anastomotic leakage after laparoscopic proctectomy can be managed by a minimally invasive approach. Dis Colon Rectum 52:91–96. https://doi.org/10.1007/DCR.0b013e3181973d7f
doi: 10.1007/DCR.0b013e3181973d7f pubmed: 19273962
Vennix S, Abegg R, Bakker OJ, van den Boezem PB, Brokelman WJ, Sietses C, Bosscha K, Lips DJ, Prins HA (2014) Surgical re-interventions following colorectal surgery: open versus laparoscopic management of anastomotic leakage. J Laparoendosc Adv Surg Tech A 23:739–774. https://doi.org/10.1089/lap.2012.0440
doi: 10.1089/lap.2012.0440
Wind J, Koopman AG, van Berge Henegouwen MI, Slors JF, Gouma DJ, Bemelman WA (2007) Laparoscopic re-intervention for anastomotic leakage after primary laparoscopic colorectal surgery. Br J Surg 94:1562–1566. https://doi.org/10.1002/BJS.5892
doi: 10.1002/BJS.5892 pubmed: 17702090
Chang KH, Bourke MG, Kavanagh DO, Neary PC, O’Riordan JM (2016) A systematic review of the role of re-laparoscopy in the management of complications following laparoscopic colorectal surgery. Surgeon 14:287–2939. https://doi.org/10.1016/j.surge.2015.12.003
doi: 10.1016/j.surge.2015.12.003 pubmed: 26805472
Wright DB, Koh CE, Solomon MJ (2017) Systematic review of the feasibility of laparoscopic reoperation for early postoperative com-plications following colorectal surgery. Br J Surg 104:337–346. https://doi.org/10.1002/bjs.10469
doi: 10.1002/bjs.10469 pubmed: 28199016
Eriksen JR, Ovesen H (2018) Gogenur I (2018) Short and long-term outcomes after colorectal anastomotic leakage is affected by surgical approach at reoperation. Int J Colorectal Dis 33:1097–1105. https://doi.org/10.1007/s00384-018-3079-6,May12
doi: 10.1007/s00384-018-3079-6,May12 pubmed: 29754169
Li YW, Lian P, Huang B, Zheng HT, Wang MH, Gu WL, Li XX, Xu Y, Cai SJ (2017) Very early colorectal anastomotic leakage within 5 post-operative days: a more severe subtype needs relaparatomy. Sci Rep 7:39936. https://doi.org/10.1038/srep39936
doi: 10.1038/srep39936 pubmed: 28084305 pmcid: 5233968
Vignali A, Elmore U, Lemma M, Guarnieri G, Radaelli G (2018) Rosati R (2018) Intracorporeal versus extracorporeal anastomoses following laparoscopic right colectomy in obese patients: a case-matched study. Dig Surg 35:236–242. https://doi.org/10.1159/000479241
doi: 10.1159/000479241 pubmed: 28768254
Cuccurullo D, Pirozzi F, Sciuto A, Bracale U, La Barbera C, Galante F, Corcione F (2015) Re-laparoscopy for management of postoperative complications following colorectal surgery: ten years experience in a single center. Surg Endosc 29:1795–1803. https://doi.org/10.1007/s00464-014-3862-6
doi: 10.1007/s00464-014-3862-6 pubmed: 25294542
Marano A, Giuffrida MC, Giraudo G, Pellegrino L, Borghi F (2016) Management of peritonitis after minimally invasive colorectal surgery. Can we stick to laparoscopy ? J Laparoendosc Adv Surg Tech 27:342–347. https://doi.org/10.1089/lap.2016.0374
doi: 10.1089/lap.2016.0374
Bakker IS, Grossmann I, Henneman D, Havenga K, Wiggers T (2014) Risk factors for anastomotic leakage and leak-related mortality after colonic cancer surgery in a nationwide audit. BJS 101:424–432. https://doi.org/10.1002/bjs.9395
doi: 10.1002/bjs.9395
Garcia-Granero A, Frasson M, Flor-Lorente B, Blanco F, Puga R, Carratalá A, Garcia-Granero E (2013) Procalcitonin and C-reactive protein as early predictors of anastomotic leak in colorectal surgery: a prospective observational study. Dis Colon Rectum. 56:475–483. https://doi.org/10.1097/DCR.0b013e31826ce825
doi: 10.1097/DCR.0b013e31826ce825 pubmed: 23478615
Daams F, Wu Z, Lahaye MJ, Jeekel J, Lange JF (2014) Prediction and diagnosis of colorectal anastomotic leakage: a systematic review of literature. World J Gastrointest Surg 6:14–26. https://doi.org/10.4240/wjgs.v6.i2.14
doi: 10.4240/wjgs.v6.i2.14 pubmed: 24600507 pmcid: 3942535
Cimitan A, Contaldo T, Malaro R, Morpurgo E (2016) The role of laparoscopy in the treatment of anastomotic leak after minimally invasive colorectal resection for cancer. Surg Laparosc Endosc Percutan Tech 26:e80. https://doi.org/10.1097/SLE.0000000000000301
doi: 10.1097/SLE.0000000000000301 pubmed: 27403618
Thornton M, Joshi H, Vimalachandran C, Heath R, Carter P, Gur U, Rooney P (2011) Management and outcome of colorectal anastomotic leaks. Int J Colorectal Dis 26:313–320. https://doi.org/10.1007/s00384-010-1094-3
doi: 10.1007/s00384-010-1094-3 pubmed: 21107847
Fraccalvieri D, Biondo S, Saez J, Millan M, Kreisler E, Golda T, Frago R, Miguel B (2012) Management of colorectal anastomotic leakage: differences between salvage and anastomotic takedown. Am J Surg 204:671–676. https://doi.org/10.1016/j.amjsurg.2010.04.022
doi: 10.1016/j.amjsurg.2010.04.022 pubmed: 21600561
Kwak JM, Kim SH, Son DN, Kim J, Lee SI, Min BW, Um JW, Moon HY (2011) The role of laparoscopic approach for anastomotic leakage after minimally invasive surgery for colorectal cancer. J Laparoendosc Adv Surg Tech A 21:29–33. https://doi.org/10.1089/lap.2010.0407
doi: 10.1089/lap.2010.0407 pubmed: 21194304

Auteurs

Andrea Vignali (A)

Department of Gastrointestinal Surgery, IRCCS San Raffaele Scientific Institute, Via Olgettina 60, 20132, Milan, Italy. vignali.andrea@hsr.it.
Vita-Salute University, San Raffaele Scientific Institute, Milan, Italy. vignali.andrea@hsr.it.

Ugo Elmore (U)

Department of Gastrointestinal Surgery, IRCCS San Raffaele Scientific Institute, Via Olgettina 60, 20132, Milan, Italy.

Francesca Aleotti (F)

Department of Gastrointestinal Surgery, IRCCS San Raffaele Scientific Institute, Via Olgettina 60, 20132, Milan, Italy.

Delpini Roberto (D)

Department of Gastrointestinal Surgery, IRCCS San Raffaele Scientific Institute, Via Olgettina 60, 20132, Milan, Italy.

Paolo Parise (P)

Department of Gastrointestinal Surgery, IRCCS San Raffaele Scientific Institute, Via Olgettina 60, 20132, Milan, Italy.

Riccardo Rosati (R)

Department of Gastrointestinal Surgery, IRCCS San Raffaele Scientific Institute, Via Olgettina 60, 20132, Milan, Italy.
Vita-Salute University, San Raffaele Scientific Institute, Milan, Italy.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH