Nutritional assessment and surgical outcomes in very elderly patients undergoing pancreaticoduodenectomy: a retrospective study.
Age Factors
Aged
Aged, 80 and over
Female
Humans
Length of Stay
Male
Middle Aged
Nutrition Assessment
Nutritional Status
Pancreatic Neoplasms
/ physiopathology
Pancreaticoduodenectomy
/ adverse effects
Patient Selection
Perioperative Care
Postoperative Complications
/ epidemiology
Prognosis
Retrospective Studies
Serum Albumin
Survival Rate
Treatment Outcome
Elderly patients
Nutritional factors
Pancreaticoduodenectomy
Journal
Surgery today
ISSN: 1436-2813
Titre abrégé: Surg Today
Pays: Japan
ID NLM: 9204360
Informations de publication
Date de publication:
Jun 2021
Jun 2021
Historique:
received:
17
07
2020
accepted:
29
09
2020
pubmed:
28
10
2020
medline:
26
10
2021
entrez:
27
10
2020
Statut:
ppublish
Résumé
To evaluate and compare the nutritional factors and clinical outcomes of pancreaticoduodenectomy between elderly and non-elderly patients. This retrospective study evaluated 122 consecutive patients who underwent pancreaticoduodenectomy from April 2008 to April 2020. Preoperative and postoperative nutritional factors (prognostic nutritional index), complication rates, and survival rates were compared between the elderly (≥ 80 years) and non-elderly (< 80 years) patient groups. Changes in nutrition markers were evaluated before surgery to 1 year after surgery. A total of 20 elderly patients (16.4%) and 102 non-elderly patients (83.6%) underwent pancreaticoduodenectomy. Elderly patients had a significantly lower preoperative prognostic nutritional index than did non-elderly patients. At 3 months postoperatively, elderly patients had a lower albumin level and prognostic nutritional index. The median length of hospital stay was significantly longer (39.9 vs. 27 days, P = 0.004), the rate of death due to other diseases was higher, and the overall survival rate was significantly lower (1-/3-/5 year overall survival rates: 78.1%/26.7%/13.3% vs. 87.1%/54.4%/46.7%; log-rank test, P = 0.003) in the elderly group than in the non-elderly group. The results suggest that careful patient selection and optimal perioperative care are necessary to determine whether pancreaticoduodenectomy is indicated for elderly patients.
Identifiants
pubmed: 33106898
doi: 10.1007/s00595-020-02169-2
pii: 10.1007/s00595-020-02169-2
doi:
Substances chimiques
Serum Albumin
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
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