Nano-optosensor based on titanium dioxide and graphene quantum dots composited with specific polymer for cefazolin detection.
Cefazolin
Fluorescence
Graphene quantum dots
Molecularly imprinted polymer
Optosensor
Titanium dioxide
Journal
Journal of pharmaceutical and biomedical analysis
ISSN: 1873-264X
Titre abrégé: J Pharm Biomed Anal
Pays: England
ID NLM: 8309336
Informations de publication
Date de publication:
30 Jan 2021
30 Jan 2021
Historique:
received:
17
08
2020
revised:
15
10
2020
accepted:
16
10
2020
pubmed:
2
11
2020
medline:
22
6
2021
entrez:
1
11
2020
Statut:
ppublish
Résumé
An optosensor using nanocomposite probes was fabricated for the detection of trace cefazolin. The nanoprobes utilized the high affinity of titanium dioxide, the good optical properties of graphene quantum dots and the good selectivity of molecularly imprinted polymer. The integration of these materials produced a rapid, highly sensitive optosensor with excellent selectivity for cefazolin detection. The fluorescence intensity of the nanocomposite probes was quenched when cefazolin re-bound with the imprinted recognition cavities of the nanoprobes. The fabricated nanoprobe exhibited a good linearity for cefazolin from 0.10 to 10.0 μg L
Identifiants
pubmed: 33130395
pii: S0731-7085(20)31601-0
doi: 10.1016/j.jpba.2020.113715
pii:
doi:
Substances chimiques
Polymers
0
titanium dioxide
15FIX9V2JP
Graphite
7782-42-5
Titanium
D1JT611TNE
Cefazolin
IHS69L0Y4T
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
113715Informations de copyright
Copyright © 2020 Elsevier B.V. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.