Linolenic acid enhances contraction induced by phenylephrine in isolated rat aorta.

Animals Aorta / drug effects Dose-Response Relationship, Drug Drug Synergism Human Umbilical Vein Endothelial Cells / drug effects Humans Male Organ Culture Techniques Phenylephrine / pharmacology Rats Rats, Sprague-Dawley Vasoconstriction / drug effects alpha-Linolenic Acid / pharmacology
Calcium Contraction Linolenic acid Nitric oxide Phenylephrine

Journal

European journal of pharmacology
ISSN: 1879-0712
Titre abrégé: Eur J Pharmacol
Pays: Netherlands
ID NLM: 1254354

Informations de publication

Date de publication:
05 Jan 2021
Historique:
received: 25 08 2020
revised: 12 10 2020
accepted: 20 10 2020
pubmed: 3 11 2020
medline: 18 5 2021
entrez: 2 11 2020
Statut: ppublish

Résumé

This study examined the effect of linolenic acid on the contraction of isolated endothelium-intact and -denuded rat aorta induced by phenylephrine and its underlying mechanism. This was conducted in the presence or absence of N

Identifiants

DOI: 10.1016/j.ejphar.2020.173662 PMID: 33131719
pubmed: 33131719
pii: S0014-2999(20)30754-8
doi: 10.1016/j.ejphar.2020.173662
pii:
doi:

Substances chimiques

alpha-Linolenic Acid 0RBV727H71
Phenylephrine 1WS297W6MV

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

173662

Informations de copyright

Copyright © 2020 Elsevier B.V. All rights reserved.

Auteurs

Soo Hee Lee (SH)

Department of Anesthesiology and Pain Medicine, Gyeongsang National University Hospital, 15 Jinju-daero 816 Beon-gil, Jinju-si, Gyeongsangnam-do, 52727, Republic of Korea.

Seong-Chun Kwon (SC)

Department of Physiology, Institute of Clinical and Translational Research, Catholic Kwandong University, College of Medicine, Gangneung, 25601, Republic of Korea.

Seong-Ho Ok (SH)

Department of Anesthesiology and Pain Medicine, Gyeongsang National University Changwon Hospital 11, Samjeongja-ro, Seongsan-gu, Changwon-si, Gyeongsangnam-do, 51472, Republic of Korea; Department of Anesthesiology and Pain Medicine, Gyeongsang National University College of Medicine, 15 Jinju-daero 816 Beon-gil, Jinju-si, Gyeongsangnam-do, 52727, Republic of Korea; Institute of Health Sciences, Gyeongsang National University, Jinju-si, 52727, Republic of Korea.

Seung Hyun Ahn (SH)

Department of Anesthesiology and Pain Medicine, Gyeongsang National University Hospital, 15 Jinju-daero 816 Beon-gil, Jinju-si, Gyeongsangnam-do, 52727, Republic of Korea.

Sung Il Bae (SI)

Department of Anesthesiology and Pain Medicine, Gyeongsang National University Hospital, 15 Jinju-daero 816 Beon-gil, Jinju-si, Gyeongsangnam-do, 52727, Republic of Korea.

Yeran Hwang (Y)

Department of Anesthesiology and Pain Medicine, Gyeongsang National University Hospital, 15 Jinju-daero 816 Beon-gil, Jinju-si, Gyeongsangnam-do, 52727, Republic of Korea.

Kyeong-Eon Park (KE)

Department of Anesthesiology and Pain Medicine, Gyeongsang National University Hospital, 15 Jinju-daero 816 Beon-gil, Jinju-si, Gyeongsangnam-do, 52727, Republic of Korea.

Ju-Tae Sohn (JT)

Department of Anesthesiology and Pain Medicine, Gyeongsang National University College of Medicine, Gyeongsang National University Hospital, 15 Jinju-daero 816 Beon-gil, Jinju-si, Gyeongsangnam-do, 52727, Republic of Korea; Institute of Health Sciences, Gyeongsang National University, Jinju-si, 52727, Republic of Korea. Electronic address: jtsohn@gnu.ac.kr.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Linolenic acid enhances contraction induced by...
questionsmedicales.fr › Système cardiovasculaire › Vaisseaux sanguins › Artères › Aorte › Linolenic acid enhances contraction induced by...
questionsmedicales.fr › Phénomènes physiologiques › Phénomènes pharmacologiques et toxicologiques › Phénomènes toxicologiques › Relation dose-effet des médicaments › Linolenic acid enhances contraction induced by...
questionsmedicales.fr › Phénomènes physiologiques › Phénomènes pharmacologiques et toxicologiques › Phénomènes pharmacologiques › Interactions médicamenteuses › Synergie des médicaments › Linolenic acid enhances contraction induced by...
questionsmedicales.fr › Cellules › Cellules épithéliales › Cellules endothéliales › Cellules endothéliales de la veine ombilicale humaine › Linolenic acid enhances contraction induced by...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Linolenic acid enhances contraction induced by...
questionsmedicales.fr › Techniques d'investigation › Techniques in vitro › Techniques de culture › Techniques de culture d'organes › Linolenic acid enhances contraction induced by...
questionsmedicales.fr › Composés chimiques organiques › Amines › Aminoalcools › Éthanolamines › Phényléphrine › Linolenic acid enhances contraction induced by...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Rats › Linolenic acid enhances contraction induced by...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Rats › Rat Sprague-Dawley › Linolenic acid enhances contraction induced by...
questionsmedicales.fr › Phénomènes physiologiques respiratoires et circulatoires › Phénomènes physiologiques cardiovasculaires › Hémodynamique › Vasoconstriction › Linolenic acid enhances contraction induced by...
questionsmedicales.fr › Lipides › Acides gras › Acides gras insaturés › Acide alpha-linolénique › Linolenic acid enhances contraction induced by...