β-Barrels covalently link peptidoglycan and the outer membrane in the α-proteobacterium Brucella abortus.


Journal

Nature microbiology
ISSN: 2058-5276
Titre abrégé: Nat Microbiol
Pays: England
ID NLM: 101674869

Informations de publication

Date de publication:
01 2021
Historique:
received: 16 12 2019
accepted: 16 09 2020
pubmed: 4 11 2020
medline: 17 3 2021
entrez: 3 11 2020
Statut: ppublish

Résumé

Gram-negative bacteria are surrounded by a cell envelope that comprises an outer membrane (OM) and an inner membrane that, together, delimit the periplasmic space, which contains the peptidoglycan (PG) sacculus. Covalent anchoring of the OM to the PG is crucial for envelope integrity in Escherichia coli. When the OM is not attached to the PG, the OM forms blebs and detaches from the cell. The Braun lipoprotein Lpp

Identifiants

pubmed: 33139884
doi: 10.1038/s41564-020-00799-3
pii: 10.1038/s41564-020-00799-3
doi:

Substances chimiques

Bacterial Outer Membrane Proteins 0
Lipoproteins 0
Peptidoglycan 0
Peptidyl Transferases EC 2.3.2.12

Banques de données

figshare
['10.6084/m9.figshare.c.5087120']

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

27-33

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Auteurs

Pierre Godessart (P)

Research Unit in Microorganisms Biology (URBM), Department of Biology, Namur Research Institute for Life Sciences (NARILIS), Namur, Belgium.

Adélie Lannoy (A)

Research Unit in Microorganisms Biology (URBM), Department of Biology, Namur Research Institute for Life Sciences (NARILIS), Namur, Belgium.

Marc Dieu (M)

MaSUN, Mass Spectrometry Facility, University of Namur, Namur, Belgium.

Sander E Van der Verren (SE)

Structural & Molecular Microbiology, VIB-VUB Centre for Structural Biology, Brussels, Belgium.
Structural Biology Brussels, Vrije Universiteit Brussel, Brussels, Belgium.

Patrice Soumillion (P)

LIBST, UCLouvain, Louvain-la-Neuve, Belgium.

Jean-François Collet (JF)

de Duve Institute, Université Catholique de Louvain, Brussels, Belgium.
WELBIO, Brussels, Belgium.

Han Remaut (H)

Structural & Molecular Microbiology, VIB-VUB Centre for Structural Biology, Brussels, Belgium.
Structural Biology Brussels, Vrije Universiteit Brussel, Brussels, Belgium.

Patricia Renard (P)

MaSUN, Mass Spectrometry Facility, University of Namur, Namur, Belgium.
Laboratory of Biochemistry and Cell Biology (URBC), Department of Biology, Namur Research Institute for Life Sciences (NARILIS), Namur, Belgium.

Xavier De Bolle (X)

Research Unit in Microorganisms Biology (URBM), Department of Biology, Namur Research Institute for Life Sciences (NARILIS), Namur, Belgium. xavier.debolle@unamur.be.

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