The Erythropoetin
epidemiology
erythropoietin
genetics
peripheral arterial disease
Journal
Genes
ISSN: 2073-4425
Titre abrégé: Genes (Basel)
Pays: Switzerland
ID NLM: 101551097
Informations de publication
Date de publication:
04 11 2020
04 11 2020
Historique:
received:
30
09
2020
revised:
29
10
2020
accepted:
30
10
2020
entrez:
7
11
2020
pubmed:
8
11
2020
medline:
24
7
2021
Statut:
epublish
Résumé
Erythropoietin has a pivotal role in erythropoiesis and angiogenesis. A common polymorphism (rs1617640, A > C) in the promoter of the erythropoietin gene (EPO) has been associated with erythropoietin expression and microvascular complications of diabetes. We aimed to analyze the potential role of this polymorphism in the pathogenesis of peripheral arterial disease (PAD). EPO genotypes and laboratory markers for erythropoiesis were determined in 945 patients with PAD. The minor EPO The EPO
Sections du résumé
BACKGROUND
Erythropoietin has a pivotal role in erythropoiesis and angiogenesis. A common polymorphism (rs1617640, A > C) in the promoter of the erythropoietin gene (EPO) has been associated with erythropoietin expression and microvascular complications of diabetes. We aimed to analyze the potential role of this polymorphism in the pathogenesis of peripheral arterial disease (PAD).
METHODS
EPO genotypes and laboratory markers for erythropoiesis were determined in 945 patients with PAD.
RESULTS
The minor EPO
CONCLUSIONS
The EPO
Identifiants
pubmed: 33158076
pii: genes11111305
doi: 10.3390/genes11111305
pmc: PMC7694227
pii:
doi:
Substances chimiques
EPO protein, human
0
Hemoglobins
0
Erythropoietin
11096-26-7
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
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