Whole genome sequencing to decipher the virulence phenotype of hypervirulent Klebsiella pneumoniae responsible for liver abscess, Marseille, France.
Hypervirulent
Klebsiella pneumoniae
Liver abscess
ST23
ST86
Journal
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology
ISSN: 1435-4373
Titre abrégé: Eur J Clin Microbiol Infect Dis
Pays: Germany
ID NLM: 8804297
Informations de publication
Date de publication:
May 2021
May 2021
Historique:
received:
18
08
2020
accepted:
21
10
2020
pubmed:
14
11
2020
medline:
21
8
2021
entrez:
13
11
2020
Statut:
ppublish
Résumé
We described three clinical cases of pyogenic liver abscess caused by hypervirulent Klebsiella pneumoniae (hvKp) successfully treated by prolonged antibiotherapy, in which one case was complicated by endophthalmitis. Whole genome sequencing helped to confirm the diagnosis of these hvKp strains, which belong to clonal complexes CC86 and CC23 and carried hvKp-associated genes (magA and/or rmpA). This syndrome is increasingly reported in France and Europe and raises questions about the source of infection.
Identifiants
pubmed: 33184752
doi: 10.1007/s10096-020-04080-7
pii: 10.1007/s10096-020-04080-7
doi:
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
1073-1077Références
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