Advances in Electrochemical Impedance Spectroscopy Detection of Endocrine Disruptors.


Journal

Sensors (Basel, Switzerland)
ISSN: 1424-8220
Titre abrégé: Sensors (Basel)
Pays: Switzerland
ID NLM: 101204366

Informations de publication

Date de publication:
11 Nov 2020
Historique:
received: 01 10 2020
revised: 01 11 2020
accepted: 09 11 2020
entrez: 14 11 2020
pubmed: 15 11 2020
medline: 7 4 2021
Statut: epublish

Résumé

Endocrine disruptors (EDs) are contaminants that may mimic or interfere with the body's hormones, hampering the normal functions of the endocrine system in humans and animals. These substances, either natural or man-made, are involved in development, breeding, and immunity, causing a wide range of diseases and disorders. The traditional detection methods such as enzyme linked immunosorbent assay (ELISA) and chromatography are still the golden techniques for EDs detection due to their high sensitivity, robustness, and accuracy. Nevertheless, they have the disadvantage of being expensive and time-consuming, requiring bulky equipment or skilled personnel. On the other hand, early stage detection of EDs on-the-field requires portable devices fulfilling the Affordable, Sensitive, Specific, User-friendly, Rapid and Robust, Equipment free, Deliverable to end users (ASSURED) norms. Electrochemical impedance spectroscopy (EIS)-based sensors can be easily implemented in fully automated, sample-to-answer devices by integrating electrodes in microfluidic chips. The latest achievements on EIS-based sensors are discussed and critically assessed.

Identifiants

pubmed: 33187314
pii: s20226443
doi: 10.3390/s20226443
pmc: PMC7697587
pii:
doi:

Substances chimiques

Endocrine Disruptors 0

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : Research Institute of the University of Bucharest (ICUB)
ID : 9737/2019

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Auteurs

Lucian-Gabriel Zamfir (LG)

R&D Center LaborQ, University of Bucharest, 4-12 Regina Elisabeta Blvd., 030018 Bucharest, Romania.

Mihaela Puiu (M)

R&D Center LaborQ, University of Bucharest, 4-12 Regina Elisabeta Blvd., 030018 Bucharest, Romania.

Camelia Bala (C)

R&D Center LaborQ, University of Bucharest, 4-12 Regina Elisabeta Blvd., 030018 Bucharest, Romania.
Department of Analytical Chemistry, University of Bucharest, 4-12 Regina Elisabeta Blvd., 030018 Bucharest, Romania.

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Classifications MeSH