N6-methyladenine and epigenetic immunity of Deinococcus radiodurans.


Journal

Research in microbiology
ISSN: 1769-7123
Titre abrégé: Res Microbiol
Pays: France
ID NLM: 8907468

Informations de publication

Date de publication:
Historique:
received: 05 07 2020
revised: 29 10 2020
accepted: 31 10 2020
pubmed: 15 11 2020
medline: 17 8 2021
entrez: 14 11 2020
Statut: ppublish

Résumé

DNA methylation is ubiquitously found in all three domains of life. This epigenetic modification on adenine or cytosine residues serves to regulate gene expression or to defend against invading DNA in bacteria. Here, we report the significance of N6-methyladenine (6mA) to epigenetic immunity in Deinococcus radiodurans. Putative protein encoded by DR_2267 ORF (Dam2

Identifiants

pubmed: 33188877
pii: S0923-2508(20)30102-9
doi: 10.1016/j.resmic.2020.10.004
pii:
doi:

Substances chimiques

DNA, Bacterial 0
N-methyladenosine CLE6G00625
Methyltransferases EC 2.1.1.-
Adenine JAC85A2161
Adenosine K72T3FS567

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

103789

Informations de copyright

Copyright © 2020 Institut Pasteur. Published by Elsevier Masson SAS. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of competing interest The authors declare that they have no conflicts of interest with the content of this article.

Auteurs

Suraj Joshi (S)

Molecular Biology Division, Bhabha Atomic Research Centre, Mumbai 400085, India; Molecular Biology Research Laboratory, Department of Zoology, SPPU, Pune 411007, India; Bioinformatics Centre, SPPU, Pune 411007, India. Electronic address: suraj.joshi1988@gmail.com.

Aman Kumar Ujaoney (AK)

Molecular Biology Division, Bhabha Atomic Research Centre, Mumbai 400085, India. Electronic address: aman@barc.gov.in.

Payel Ghosh (P)

Bioinformatics Centre, SPPU, Pune 411007, India. Electronic address: payelghosh@gmail.com.

Deepti D Deobagkar (DD)

Molecular Biology Research Laboratory, Department of Zoology, SPPU, Pune 411007, India. Electronic address: deepti.deobagkar@gmail.com.

Bhakti Basu (B)

Molecular Biology Division, Bhabha Atomic Research Centre, Mumbai 400085, India; Homi Bhabha National Institute, Training School Complex, Anushakti Nagar, Mumbai 400094, India. Electronic address: bbasu@barc.gov.in.

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