Comparative analyses of the Pan lineage reveal selection on gene pathways associated with diet and sociality in bonobos.
anthropology
bonobos
chimpanzees
genetics
gonadotropin
natural selection
oxytocin, population
primatology
selection scans
whole genomes
Journal
Genes, brain, and behavior
ISSN: 1601-183X
Titre abrégé: Genes Brain Behav
Pays: England
ID NLM: 101129617
Informations de publication
Date de publication:
03 2021
03 2021
Historique:
received:
01
07
2020
revised:
10
11
2020
accepted:
16
11
2020
pubmed:
18
11
2020
medline:
15
2
2022
entrez:
17
11
2020
Statut:
ppublish
Résumé
Chimpanzees (Pan troglodytes) and bonobos (Pan paniscus) diverged into distinct species approximately 1.7 million years ago when the ancestors of modern-day bonobo populations were separated by the Congo River. This geographic boundary separates the two species today and the associated ecological factors, including resource distribution and feeding competition, have likely shaped the divergent social behavior of both species. The most striking behavioral differences pertain to between group interactions in which chimpanzees behave aggressively towards unfamiliar conspecifics, while bonobos display remarkable tolerance. Several hypotheses attempt to explain how different patterns of social behavior have come to exist in the two species, some with specific genetic predictions, likening the evolution of bonobos to a process of domestication. Here, we utilize 73 ape genomes and apply linkage haplotype homozygosity and structure informed allele frequency differentiation methods to identify positively selected regions in bonobos since their split from a common pan ancestor to better understand the environment and processes that resulted in the behavioral differences observed today. We find novel evidence of selection in genetic regions that aid in starch digestion (AMY2) along with support for two genetic predictions related to self-domestication processes hypothesized to have occurred in the bonobo. We also find evidence for selection on neuroendocrine pathways associated with social behavior including the oxytocin, serotonin, and gonadotropin releasing hormone pathways.
Substances chimiques
Serotonin
333DO1RDJY
Oxytocin
50-56-6
Pancreatic alpha-Amylases
EC 3.2.1.1
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
e12715Informations de copyright
© 2020 John Wiley & Sons Ltd and International Behavioural and Neural Genetics Society.
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