Deletion of LORF9 but not LORF10 attenuates Marek's disease virus pathogenesis.

Animals Cells, Cultured Chick Embryo / cytology Chickens / virology Fibroblasts / virology Gene Deletion Herpesvirus 2, Gallid / genetics Marek Disease / virology Open Reading Frames Poultry Diseases / virology Viral Proteins / genetics Virus Replication / genetics
LORF10 LORF9 Marek’s disease virus Pathogenesis Virus replication

Journal

Veterinary microbiology
ISSN: 1873-2542
Titre abrégé: Vet Microbiol
Pays: Netherlands
ID NLM: 7705469

Informations de publication

Date de publication:
Dec 2020
Historique:
received: 10 09 2020
accepted: 26 10 2020
pubmed: 20 11 2020
medline: 16 7 2021
entrez: 19 11 2020
Statut: ppublish

Résumé

Marek's disease virus (MDV) genome contains a number of uncharacterized long open reading frames (LORF) and their role in viral pathogenesis has not been fully investigated. Among them, LORF9 (MDV069) and LORF10 (MDV071) are locate at the right terminus of the MDV genome unique long region (U

Identifiants

DOI: 10.1016/j.vetmic.2020.108911 PMID: 33212362
pubmed: 33212362
pii: S0378-1135(20)31049-X
doi: 10.1016/j.vetmic.2020.108911
pii:
doi:

Substances chimiques

Viral Proteins 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

108911

Informations de copyright

Copyright © 2020 Elsevier B.V. All rights reserved.

Auteurs

Yifei Liao (Y)

Department of Veterinary Pathobiology, College of Veterinary Medicine & Biomedical Sciences, Texas A&M University, College Station, TX, USA.

Aijun Sun (A)

Department of Veterinary Pathobiology, College of Veterinary Medicine & Biomedical Sciences, Texas A&M University, College Station, TX, USA.

Guoqing Zhuang (G)

Department of Veterinary Pathobiology, College of Veterinary Medicine & Biomedical Sciences, Texas A&M University, College Station, TX, USA.

Blanca Lupiani (B)

Department of Veterinary Pathobiology, College of Veterinary Medicine & Biomedical Sciences, Texas A&M University, College Station, TX, USA.

Sanjay M Reddy (SM)

Department of Veterinary Pathobiology, College of Veterinary Medicine & Biomedical Sciences, Texas A&M University, College Station, TX, USA. Electronic address: SReddy@cvm.tamu.edu.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Deletion of LORF9 but not LORF10 attenuates...
questionsmedicales.fr › Cellules › Cellules cultivées › Deletion of LORF9 but not LORF10 attenuates...
questionsmedicales.fr › Structures de l'embryon › Embryon non mammalien › Embryon de poulet › Deletion of LORF9 but not LORF10 attenuates...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Oiseaux › Poulets › Deletion of LORF9 but not LORF10 attenuates...
questionsmedicales.fr › Cellules › Cellules du tissu conjonctif › Fibroblastes › Deletion of LORF9 but not LORF10 attenuates...
questionsmedicales.fr › Phénomènes génétiques › Mutagenèse › Délétion de séquence › Délétion de gène › Deletion of LORF9 but not LORF10 attenuates...
questionsmedicales.fr › Virus › Virus à ADN › Herpesviridae › Alphaherpesvirinae › Mardivirus › Herpèsvirus aviaire de type 2 › Deletion of LORF9 but not LORF10 attenuates...
questionsmedicales.fr › Maladies de l'animal › Maladies des oiseaux › Maladie de Marek › Deletion of LORF9 but not LORF10 attenuates...
questionsmedicales.fr › Phénomènes génétiques › Structures génétiques › Génome › Composants de génome › Gènes › Composants de gène › Cadres ouverts de lecture › Deletion of LORF9 but not LORF10 attenuates...
questionsmedicales.fr › Maladies de l'animal › Maladies des oiseaux › Maladies de la volaille › Deletion of LORF9 but not LORF10 attenuates...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines virales › Deletion of LORF9 but not LORF10 attenuates...
questionsmedicales.fr › Phénomènes microbiologiques › Phénomènes physiologiques viraux › Réplication virale › Deletion of LORF9 but not LORF10 attenuates...