FlyBase: updates to the Drosophila melanogaster knowledge base.

Animals Computational Biology / methods Databases, Genetic Drosophila melanogaster / genetics Genes, Insect / genetics Genome, Insect / genetics Genomics / methods Knowledge Bases Molecular Sequence Annotation / methods Search Engine / methods Web Browser

Journal

Nucleic acids research
ISSN: 1362-4962
Titre abrégé: Nucleic Acids Res
Pays: England
ID NLM: 0411011

Informations de publication

Date de publication:
08 01 2021
Historique:
accepted: 22 10 2020
revised: 13 10 2020
received: 15 09 2020
pubmed: 22 11 2020
medline: 2 2 2021
entrez: 21 11 2020
Statut: ppublish

Résumé

FlyBase (flybase.org) is an essential online database for researchers using Drosophila melanogaster as a model organism, facilitating access to a diverse array of information that includes genetic, molecular, genomic and reagent resources. Here, we describe the introduction of several new features at FlyBase, including Pathway Reports, paralog information, disease models based on orthology, customizable tables within reports and overview displays ('ribbons') of expression and disease data. We also describe a variety of recent important updates, including incorporation of a developmental proteome, upgrades to the GAL4 search tab, additional Experimental Tool Reports, migration to JBrowse for genome browsing and improvements to batch queries/downloads and the Fast-Track Your Paper tool.

Identifiants

DOI: 10.1093/nar/gkaa1026 PMID: 33219682 PMC: PMC7779046
pubmed: 33219682
pii: 5997437
doi: 10.1093/nar/gkaa1026
pmc: PMC7779046
doi:

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

D899-D907

Subventions

Organisme : Medical Research Council
ID : MR/N030117/1
Pays : United Kingdom
Organisme : NHGRI NIH HHS
ID : U41 HG000739
Pays : United States

Investigateurs

Norbert Perrimon (N)
Susan Russo Gelbart (SR)
Julie Agapite (J)
Kris Broll (K)
Madeline Crosby (M)
Gilberto Dos Santos (G)
Kathleen Falls (K)
L Sian Gramates (LS)
Victoria Jenkins (V)
Ian Longden (I)
Beverley Matthews (B)
Carol Sutherland (C)
Christopher J Tabone (CJ)
Pinglei Zhou (P)
Mark Zytkovicz (M)
Nick Brown (N)
Giulia Antonazzo (G)
Helen Attrill (H)
Phani Garapati (P)
Aoife Larkin (A)
Steven Marygold (S)
Alex McLachlan (A)
Gillian Millburn (G)
Clare Pilgrim (C)
Arzu Ozturk-Colak (A)
Vitor Trovisco (V)
Thomas Kaufman (T)
Brian Calvi (B)
Josh Goodman (J)
Victor Strelets (V)
Jim Thurmond (J)
Richard Cripps (R)
TyAnna Lovato (T)

Informations de copyright

© The Author(s) 2020. Published by Oxford University Press on behalf of Nucleic Acids Research.

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Auteurs

Aoife Larkin (A)

Department of Physiology, Development and Neuroscience, University of Cambridge, Downing Street, Cambridge CB2 3DY, UK.

Steven J Marygold (SJ)

Department of Physiology, Development and Neuroscience, University of Cambridge, Downing Street, Cambridge CB2 3DY, UK.

Giulia Antonazzo (G)

Department of Physiology, Development and Neuroscience, University of Cambridge, Downing Street, Cambridge CB2 3DY, UK.

Helen Attrill (H)

Department of Physiology, Development and Neuroscience, University of Cambridge, Downing Street, Cambridge CB2 3DY, UK.

Gilberto Dos Santos (G)

The Biological Laboratories, Harvard University, 16 Divinity Avenue, Cambridge, MA 02138, USA.

Phani V Garapati (PV)

Department of Physiology, Development and Neuroscience, University of Cambridge, Downing Street, Cambridge CB2 3DY, UK.

Joshua L Goodman (JL)

Department of Biology, Indiana University, Bloomington, IN 47405, USA.

L Sian Gramates (LS)

The Biological Laboratories, Harvard University, 16 Divinity Avenue, Cambridge, MA 02138, USA.

Gillian Millburn (G)

Department of Physiology, Development and Neuroscience, University of Cambridge, Downing Street, Cambridge CB2 3DY, UK.

Victor B Strelets (VB)

Department of Biology, Indiana University, Bloomington, IN 47405, USA.

Christopher J Tabone (CJ)

The Biological Laboratories, Harvard University, 16 Divinity Avenue, Cambridge, MA 02138, USA.

Jim Thurmond (J)

Department of Biology, Indiana University, Bloomington, IN 47405, USA.

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