Ustilago maydis effector Jsi1 interacts with Topless corepressor, hijacking plant jasmonate/ethylene signaling.
Ustilago maydis
EAR motif
Jsi1
Topless
ethylene response factor
jasmonate/ethylene (JA/ET) signaling
Journal
The New phytologist
ISSN: 1469-8137
Titre abrégé: New Phytol
Pays: England
ID NLM: 9882884
Informations de publication
Date de publication:
03 2021
03 2021
Historique:
received:
17
10
2020
accepted:
16
11
2020
pubmed:
29
11
2020
medline:
15
5
2021
entrez:
28
11
2020
Statut:
ppublish
Résumé
Ustilago maydis is the causal agent of maize smut disease. During the colonization process, the fungus secretes effector proteins that suppress immune responses and redirect the host metabolism in favor of the pathogen. As effectors play a critical role during plant colonization, their identification and functional characterization are essential to understanding biotrophy and disease. Using biochemical, molecular, and transcriptomic techniques, we performed a functional characterization of the U. maydis effector Jasmonate/Ethylene signaling inducer 1 (Jsi1). Jsi1 interacts with several members of the plant corepressor family Topless/Topless related (TPL/TPR). Jsi1 expression in Zea mays and Arabidopsis thaliana leads to transcriptional induction of the ethylene response factor (ERF) branch of the jasmonate/ethylene (JA/ET) signaling pathway. In A. thaliana, activation of the ERF branch leads to biotrophic susceptibility. Jsi1 likely activates the ERF branch via an EAR (ET-responsive element binding-factor-associated amphiphilic repression) motif, which resembles EAR motifs from plant ERF transcription factors, that interacts with TPL/TPR proteins. EAR-motif-containing effector candidates were identified from different fungal species, including Magnaporthe oryzae, Sporisorium scitamineum, and Sporisorium reilianum. Interaction between plant TPL proteins and these effector candidates from biotrophic and hemibiotrophic fungi indicates the convergent evolution of effectors modulating the TPL/TPR corepressor hub.
Identifiants
pubmed: 33247447
doi: 10.1111/nph.17116
pmc: PMC8126959
doi:
Substances chimiques
Co-Repressor Proteins
0
Cyclopentanes
0
Ethylenes
0
Fungal Proteins
0
Oxylipins
0
jasmonic acid
6RI5N05OWW
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
3393-3407Informations de copyright
© 2020 The Authors New Phytologist © 2020 New Phytologist Foundation.
Références
PLoS Pathog. 2016 Jun 22;12(6):e1005697
pubmed: 27332891
PLoS Biol. 2014 Feb 18;12(2):e1001792
pubmed: 24558350
Cell Host Microbe. 2013 Feb 13;13(2):143-54
pubmed: 23414755
Plant Physiol. 2010 Mar;152(3):1109-34
pubmed: 20097792
Cell Host Microbe. 2017 Feb 8;21(2):156-168
pubmed: 28132837
Nat Commun. 2018 Apr 27;9(1):1711
pubmed: 29703884
PLoS One. 2011;6(4):e18556
pubmed: 21602908
Plant Cell. 2007 Jul;19(7):2225-45
pubmed: 17616737
Nature. 2011 Oct 05;478(7369):395-8
pubmed: 21976020
Nature. 2006 Nov 2;444(7115):97-101
pubmed: 17080091
Genetics. 2009 Nov;183(3):979-1003
pubmed: 19752216
PLoS One. 2012;7(4):e35995
pubmed: 22563431
Plant Mol Biol Report. 2015;33:624-637
pubmed: 26696694
Plant J. 2008 Oct;56(2):181-195
pubmed: 18564380
Plant Physiol. 2008 Jul;147(3):1347-57
pubmed: 18467450
Nucleic Acids Res. 2015 Jan;43(Database issue):D1003-9
pubmed: 25414324
Plant Biotechnol J. 2007 Mar;5(2):313-24
pubmed: 17309686
Nat Plants. 2018 Mar;4(3):172-180
pubmed: 29483684
Mol Plant Microbe Interact. 2015 Apr;28(4):455-66
pubmed: 25372120
Nature. 2010 Apr 1;464(7289):788-91
pubmed: 20360743
Bioinformatics. 2014 Aug 1;30(15):2114-20
pubmed: 24695404
Genome Biol. 2014;15(12):550
pubmed: 25516281
Nat Rev Microbiol. 2017 Jul;15(7):409-421
pubmed: 28479603
Plant Mol Biol. 2014 Nov;86(4-5):543-54
pubmed: 25209110
Plant Cell. 2003 Jan;15(1):165-78
pubmed: 12509529
Methods Mol Biol. 2012;835:61-74
pubmed: 22183647
Plant Physiol. 2012 Jan;158(1):423-38
pubmed: 22065421
Proc Natl Acad Sci U S A. 2014 Jun 3;111(22):8299-304
pubmed: 24847068
Plant Physiol. 2005 Oct;139(2):949-59
pubmed: 16183832
Mol Genet Genomics. 2003 Dec;270(4):303-14
pubmed: 14523645
Plant Signal Behav. 2012 Mar;7(3):325-8
pubmed: 22476455
Plant Sci. 2013 Dec;213:79-87
pubmed: 24157210
Front Plant Sci. 2017 Jul 11;8:1210
pubmed: 28744297
Front Plant Sci. 2014 Nov 11;5:611
pubmed: 25426127
Cold Spring Harb Symp Quant Biol. 2012;77:235-47
pubmed: 23223409
Mol Plant Pathol. 2014 Aug;15(6):589-600
pubmed: 24387225
Proc Natl Acad Sci U S A. 2010 Aug 3;107(31):13960-5
pubmed: 20647385
Plant Cell. 2004 Feb;16(2):319-31
pubmed: 14742872
Front Plant Sci. 2015 Mar 25;6:170
pubmed: 25859250
Bioinformatics. 2013 Jan 1;29(1):15-21
pubmed: 23104886
Plant Cell. 2018 Feb;30(2):300-323
pubmed: 29371439
Proc Natl Acad Sci U S A. 2017 Jul 25;114(30):8107-8112
pubmed: 28698367
Nat Chem Biol. 2015 Sep;11(9):733-40
pubmed: 26258762
Cell. 2016 May 19;165(5):1280-1292
pubmed: 27203113
Plant Cell. 2013 Feb;25(2):744-61
pubmed: 23435661
Methods. 2001 Dec;25(4):402-8
pubmed: 11846609
Mol Microbiol. 2001 Nov;42(4):1047-63
pubmed: 11737646
Plant Cell. 2001 Aug;13(8):1959-68
pubmed: 11487705
Annu Rev Cell Dev Biol. 2012;28:489-521
pubmed: 22559264
Science. 2006 Jun 9;312(5779):1520-3
pubmed: 16763149
Plant Cell. 2015 Apr;27(4):1332-51
pubmed: 25888589
J Biol Chem. 2008 Oct 3;283(40):26996-7006
pubmed: 18693252
Science. 2008 Mar 7;319(5868):1384-6
pubmed: 18258861
Plant J. 2020 Jul;103(1):412-429
pubmed: 32168401
Front Plant Sci. 2017 Aug 02;8:1330
pubmed: 28824668
Cell Mol Life Sci. 2020 Oct;77(20):3963-3976
pubmed: 32277261
Annu Rev Plant Biol. 2018 Apr 29;69:387-415
pubmed: 29539269
Plant Physiol. 2018 Aug;177(4):1352-1367
pubmed: 29880705
Plant Physiol. 2019 Jan;179(1):348-363
pubmed: 30348817
Plant Physiol. 2005 Sep;139(1):5-17
pubmed: 16166256