Crystal structure of barley agmatine coumaroyltransferase, an N-acyltransferase from the BAHD superfamily.
BAHD superfamily
Hordeum vulgare
N-acyltransferases
agmatine coumaroyltransferase
Journal
Acta crystallographica. Section F, Structural biology communications
ISSN: 2053-230X
Titre abrégé: Acta Crystallogr F Struct Biol Commun
Pays: United States
ID NLM: 101620319
Informations de publication
Date de publication:
01 Dec 2020
01 Dec 2020
Historique:
received:
14
09
2020
accepted:
09
11
2020
entrez:
2
12
2020
pubmed:
3
12
2020
medline:
25
8
2021
Statut:
ppublish
Résumé
The enzymes of the BAHD superfamily, a large group of acyl-CoA-dependent acyltransferases in plants, are involved in the biosynthesis of diverse secondary metabolites. While the structures of several O-acyltransferases from the BAHD superfamily, such as hydroxycinnamoyl-CoA shikimate hydroxycinnamoyl transferase, have been elucidated, no structural information on N-acyltransferases is available. Hordeum vulgare agmatine coumaroyltransferase (HvACT) is an N-acyltransferase from the BAHD superfamily and is one of the most important enzymes in the secondary metabolism of barley. Here, an apo-form structure of HvACT is reported as the first structure of an N-acyltransferase from the BAHD superfamily. HvACT crystals diffracted to 1.8 Å resolution and belonged to the monoclinic space group P2
Identifiants
pubmed: 33263570
pii: S2053230X20014880
doi: 10.1107/S2053230X20014880
pmc: PMC7716262
doi:
Substances chimiques
Plant Proteins
0
Solvents
0
Acyltransferases
EC 2.3.-
agmatine coumaroyltransferase
EC 2.3.1.64
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
590-596Références
Curr Opin Plant Biol. 2006 Jun;9(3):331-40
pubmed: 16616872
New Phytol. 2015 Nov;208(3):695-707
pubmed: 26053460
J Comput Chem. 2004 Oct;25(13):1605-12
pubmed: 15264254
Planta. 2012 Sep;236(3):781-93
pubmed: 22610270
Proteins. 2003 Feb 15;50(3):437-50
pubmed: 12557186
Nat Protoc. 2008;3(7):1171-9
pubmed: 18600222
Sci Rep. 2018 Sep 4;8(1):13203
pubmed: 30181615
Plant Cell. 2016 Jul;28(7):1533-50
pubmed: 27354554
Biochemistry. 2003 Feb 18;42(6):1764-71
pubmed: 12578391
Acta Crystallogr D Biol Crystallogr. 2010 Feb;66(Pt 2):125-32
pubmed: 20124692
Acta Crystallogr D Biol Crystallogr. 2013 Jul;69(Pt 7):1204-14
pubmed: 23793146
Anal Biochem. 2002 Mar 15;302(2):305-12
pubmed: 11878812
Structure. 1997 Aug 15;5(8):1093-108
pubmed: 9309224
J Biol Chem. 2005 Apr 8;280(14):13576-83
pubmed: 15665331
J Biol Chem. 2007 May 25;282(21):15812-22
pubmed: 17383962
Acta Crystallogr D Biol Crystallogr. 2011 Apr;67(Pt 4):235-42
pubmed: 21460441
PLoS Comput Biol. 2018 Oct 26;14(10):e1006511
pubmed: 30365487
BMC Genomics. 2011 May 12;12:236
pubmed: 21569431
Acta Crystallogr D Biol Crystallogr. 2011 Apr;67(Pt 4):355-67
pubmed: 21460454
Acta Crystallogr D Biol Crystallogr. 2006 Jan;62(Pt 1):72-82
pubmed: 16369096
Protein Sci. 2007 Jan;16(1):52-68
pubmed: 17192588
Anal Biochem. 1976 May 7;72:248-54
pubmed: 942051
J Biol Chem. 2003 Apr 18;278(16):13919-27
pubmed: 12582168
Plant Physiol. 2012 Sep;160(1):249-60
pubmed: 22822210
Biochemistry. 2016 Nov 15;55(45):6314-6326
pubmed: 27805809
Acta Crystallogr D Biol Crystallogr. 2010 Apr;66(Pt 4):486-501
pubmed: 20383002
Plant Cell Physiol. 2016 Mar;57(3):568-79
pubmed: 26858288
Plant Physiol. 2013 Jun;162(2):640-51
pubmed: 23624856