Dietary exposure assessment and risk characterization of citrinin and ochratoxin A in Belgium.


Journal

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
ISSN: 1873-6351
Titre abrégé: Food Chem Toxicol
Pays: England
ID NLM: 8207483

Informations de publication

Date de publication:
Jan 2021
Historique:
received: 25 09 2020
revised: 29 11 2020
accepted: 02 12 2020
pubmed: 12 12 2020
medline: 16 6 2021
entrez: 11 12 2020
Statut: ppublish

Résumé

Exposure to mycotoxins is a worldwide problem. To ensure public health, it is imperative to characterize the risks related to these toxins. The present study aims to conduct a dietary exposure assessment of citrinin (CIT) and ochratoxin A (OTA) in the Belgian population using consumption data of a variety of foodstuffs. A total of 367 food samples from different food categories were collected in Belgian supermarkets and analysed for CIT and OTA using a validated liquid chromatography-tandem mass spectrometry method. Daily CIT and OTA exposure to the Belgian population was calculated based on the analytical results and food consumption data in three age categories (3-9, 10-17 and 18-64 years), obtained from a national food consumption survey. Furthermore, a risk characterization was performed for CIT, in which no intake values exceeded the tolerable daily intake (TDI) of 200 ng kg

Identifiants

pubmed: 33307117
pii: S0278-6915(20)30804-8
doi: 10.1016/j.fct.2020.111914
pii:
doi:

Substances chimiques

Ochratoxins 0
ochratoxin A 1779SX6LUY
Citrinin 3S697X6SNZ

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

111914

Informations de copyright

Copyright © 2020 Elsevier Ltd. All rights reserved.

Auteurs

Celine Meerpoel (C)

Ghent University, Faculty of Pharmaceutical Sciences, Department of Bioanalysis, Centre of Excellence in Mycotoxicology and Public Health, Ottergemsesteenweg 460, 9000, Ghent, Belgium; Ghent University, Faculty of Veterinary Medicine, Department of Pharmacology, Toxicology and Biochemistry, Salisburylaan 133, 9820, Merelbeke, Belgium.

Arnau Vidal (A)

Ghent University, Faculty of Pharmaceutical Sciences, Department of Bioanalysis, Centre of Excellence in Mycotoxicology and Public Health, Ottergemsesteenweg 460, 9000, Ghent, Belgium.

Mirjana Andjelkovic (M)

SCIENSANO, Chemical and Physical Health Risks, Organic Contaminants and Additives, Leuvensesteenweg 17, 3080, Tervuren, Belgium.

Marthe De Boevre (M)

Ghent University, Faculty of Pharmaceutical Sciences, Department of Bioanalysis, Centre of Excellence in Mycotoxicology and Public Health, Ottergemsesteenweg 460, 9000, Ghent, Belgium.

Emmanuel K Tangni (EK)

SCIENSANO, Chemical and Physical Health Risks, Organic Contaminants and Additives, Leuvensesteenweg 17, 3080, Tervuren, Belgium.

Bart Huybrechts (B)

SCIENSANO, Chemical and Physical Health Risks, Organic Contaminants and Additives, Leuvensesteenweg 17, 3080, Tervuren, Belgium.

Mathias Devreese (M)

Ghent University, Faculty of Veterinary Medicine, Department of Pharmacology, Toxicology and Biochemistry, Salisburylaan 133, 9820, Merelbeke, Belgium.

Siska Croubels (S)

Ghent University, Faculty of Veterinary Medicine, Department of Pharmacology, Toxicology and Biochemistry, Salisburylaan 133, 9820, Merelbeke, Belgium.

Sarah De Saeger (S)

Ghent University, Faculty of Pharmaceutical Sciences, Department of Bioanalysis, Centre of Excellence in Mycotoxicology and Public Health, Ottergemsesteenweg 460, 9000, Ghent, Belgium; University of Johannesburg, Faculty of Science, Department of Biotechnology and Food Technology, P.O. Box 17011, Doornfontein Campus, Gauteng, 2028, South Africa. Electronic address: sarah.desaeger@ugent.be.

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Classifications MeSH