Visual outcomes after cataract surgery: topical nonsteroidal anti-inflammatory drug prophylaxis compared with prednisolone.
Journal
Journal of cataract and refractive surgery
ISSN: 1873-4502
Titre abrégé: J Cataract Refract Surg
Pays: United States
ID NLM: 8604171
Informations de publication
Date de publication:
01 Jul 2021
01 Jul 2021
Historique:
received:
17
07
2020
accepted:
23
11
2020
pubmed:
15
12
2020
medline:
28
7
2021
entrez:
14
12
2020
Statut:
ppublish
Résumé
To compare visual outcomes in patients without a history of macular edema after phacoemulsification using combination topical nonsteroidal anti-inflammatory drug plus prednisolone with prednisolone alone. Kaiser Permanente Northern California, USA. Retrospective cohort study. Information was obtained from the electronic health record. The first measure of corrected distance visual acuity (CDVA) recorded during the period 3 weeks to 1 year after phacoemulsification was obtained. Confounding factors and clustering of eyes within patients were adjusted using linear mixed effects regression models for the continuous outcome of CDVA improvement and general estimating equations for the dichotomous outcome of 20/20 or better vs 20/25 or worse. The study included 62 700 health plan members of whom 26,309 (42%) used topical prednisolone alone, whereas 36,391 (58%) used combination treatment. The mean within-person change in CDVA from the preoperative measurement to the postoperative measurement was the same (-0.43 logMAR) for patients in the 2 groups. However, the group that received combination treatment was somewhat more likely to achieve CDVA of 20/20 or better (odds ratio 1.24 with 95% CI, 1.20-1.28). In this large study of cataract surgery patients, a small statistically significant association of combination treatment compared with prednisolone alone was observed.
Identifiants
pubmed: 33315744
pii: 02158034-202107000-00008
doi: 10.1097/j.jcrs.0000000000000542
doi:
Substances chimiques
Anti-Inflammatory Agents, Non-Steroidal
0
Pharmaceutical Preparations
0
Prednisolone
9PHQ9Y1OLM
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
870-877Informations de copyright
Copyright © 2021 Published by Wolters Kluwer on behalf of ASCRS and ESCRS.
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