Optogenetics: The Art of Illuminating Complex Signaling Pathways.
optogenetics
signaling
Journal
Physiology (Bethesda, Md.)
ISSN: 1548-9221
Titre abrégé: Physiology (Bethesda)
Pays: United States
ID NLM: 101208185
Informations de publication
Date de publication:
01 01 2021
01 01 2021
Historique:
entrez:
16
12
2020
pubmed:
17
12
2020
medline:
29
10
2021
Statut:
ppublish
Résumé
Dissection of cell signaling requires tools that can mimic spatiotemporal dynamics of individual pathways in living cells. Optogenetic methods enable manipulation of signaling processes with precise timing and local control. In this review, we describe recent optogenetic approaches for regulation of cell signaling, highlight their advantages and limitations, and discuss examples of their application.
Identifiants
pubmed: 33325819
doi: 10.1152/physiol.00022.2020
pmc: PMC8425415
doi:
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
52-60Subventions
Organisme : NCI NIH HHS
ID : R21 CA212907
Pays : United States
Organisme : NCI NIH HHS
ID : R21 CA223915
Pays : United States
Organisme : NHLBI NIH HHS
ID : T32 HL007829
Pays : United States
Organisme : NCI NIH HHS
ID : R21 CA159179
Pays : United States
Organisme : NIGMS NIH HHS
ID : R01 GM118582
Pays : United States
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