Cortical thickness of primary visual cortex correlates with motion deficits in periventricular leukomalacia.


Journal

Neuropsychologia
ISSN: 1873-3514
Titre abrégé: Neuropsychologia
Pays: England
ID NLM: 0020713

Informations de publication

Date de publication:
22 01 2021
Historique:
received: 27 04 2020
revised: 27 11 2020
accepted: 04 12 2020
pubmed: 18 12 2020
medline: 25 6 2021
entrez: 17 12 2020
Statut: ppublish

Résumé

Impairments of visual motion perception and, in particular, of flow motion have been consistently observed in premature and very low birth weight subjects during infancy. Flow motion information is analyzed at various cortical levels along the dorsal pathways, with information mainly provided by primary and early visual cortex (V1, V2 and V3). We investigated the cortical stage of the visual processing that underlies these motion impairments, measuring Grey Matter Volume and Cortical Thickness in 13 children with Periventricular Leukomalacia (PVL). The cortical thickness, but not the grey matter volume of area V1, correlates negatively with motion coherence sensitivity, indicating that the thinner the cortex, the better the performance among the patients. However, we did not find any such association with either the thickness or volume of area MT, MST and areas of the IPS, suggesting damage at the level of primary visual cortex or along the optic radiation.

Identifiants

pubmed: 33333138
pii: S0028-3932(20)30389-4
doi: 10.1016/j.neuropsychologia.2020.107717
pii:
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

107717

Informations de copyright

Copyright © 2020 The Author(s). Published by Elsevier Ltd.. All rights reserved.

Auteurs

Akshatha Bhat (A)

Department of Developmental Neuroscience, Laboratory of Vision, IRCCS Fondazione Stella Maris, Pisa, Italy; Department of Neuroscience, University of Florence, Italy.

Laura Biagi (L)

Laboratory of Medical Physics and Magnetic Resonance, IRCCS Fondazione Stella Maris, Pisa, Italy.

Giovanni Cioni (G)

Department of Developmental Neuroscience, Laboratory of Vision, IRCCS Fondazione Stella Maris, Pisa, Italy; Department of Clinical and Experimental Medicine, University of Pisa, Italy.

Francesca Tinelli (F)

Department of Developmental Neuroscience, Laboratory of Vision, IRCCS Fondazione Stella Maris, Pisa, Italy.

M Concetta Morrone (MC)

Department of Developmental Neuroscience, Laboratory of Vision, IRCCS Fondazione Stella Maris, Pisa, Italy; Department of Translational Research on New Technologies in Medicine and Surgery, University of Pisa, Italy. Electronic address: concetta.morrone@unipi.it.

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