Les conditions de santé maternelles influencent-elles le risque ?
Oui, des conditions comme le diabète ou l'hypertension peuvent augmenter le risque de leucomalacie.
Conditions de santé maternellesLeucomalacie périventriculaireDiabète
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"name": "Comment diagnostique-t-on la leucomalacie périventriculaire ?",
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"text": "Le diagnostic se fait par IRM cérébrale, montrant des lésions dans la substance blanche."
}
},
{
"@type": "Question",
"name": "Quels signes cliniques indiquent une leucomalacie ?",
"position": 2,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des signes comme des troubles moteurs ou des retards de développement peuvent indiquer la maladie."
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"@type": "Question",
"name": "Quels examens complémentaires sont utiles ?",
"position": 3,
"acceptedAnswer": {
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"text": "Des échographies cérébrales peuvent être réalisées pour évaluer les ventricules et la substance blanche."
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"@type": "Question",
"name": "La leucomalacie est-elle visible à la naissance ?",
"position": 4,
"acceptedAnswer": {
"@type": "Answer",
"text": "Non, elle peut ne pas être détectée immédiatement et se révéler plus tard par des symptômes."
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{
"@type": "Question",
"name": "Quel est le rôle des antécédents médicaux dans le diagnostic ?",
"position": 5,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les antécédents de prématurité ou d'hypoxie sont des facteurs de risque importants à considérer."
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{
"@type": "Question",
"name": "Quels sont les symptômes courants de la leucomalacie ?",
"position": 6,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les symptômes incluent des troubles moteurs, des retards de développement et des crises."
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"@type": "Question",
"name": "Comment se manifestent les troubles moteurs ?",
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"text": "Ils peuvent se manifester par une faiblesse musculaire ou des mouvements anormaux."
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"@type": "Question",
"name": "Les retards de développement sont-ils fréquents ?",
"position": 8,
"acceptedAnswer": {
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"text": "Oui, les enfants peuvent présenter des retards dans le langage, la motricité et les compétences sociales."
}
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{
"@type": "Question",
"name": "Y a-t-il des signes neurologiques associés ?",
"position": 9,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des signes comme des réflexes anormaux ou une hypertonie peuvent être présents."
}
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{
"@type": "Question",
"name": "Les symptômes varient-ils d'un enfant à l'autre ?",
"position": 10,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'intensité et la nature des symptômes peuvent varier considérablement entre les enfants."
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"@type": "Question",
"name": "Peut-on prévenir la leucomalacie périventriculaire ?",
"position": 11,
"acceptedAnswer": {
"@type": "Answer",
"text": "La prévention passe par une bonne gestion des grossesses à risque et des soins néonatals."
}
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{
"@type": "Question",
"name": "Quel rôle joue la nutrition maternelle ?",
"position": 12,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une nutrition adéquate pendant la grossesse peut réduire le risque de complications néonatales."
}
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{
"@type": "Question",
"name": "Les soins intensifs néonatals aident-ils ?",
"position": 13,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des soins intensifs appropriés peuvent diminuer le risque de leucomalacie chez les prématurés."
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{
"@type": "Question",
"name": "Les infections maternelles influencent-elles le risque ?",
"position": 14,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les infections pendant la grossesse peuvent augmenter le risque de complications cérébrales."
}
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{
"@type": "Question",
"name": "Le suivi prénatal est-il important ?",
"position": 15,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, un suivi prénatal régulier permet de détecter et de gérer les risques potentiels."
}
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{
"@type": "Question",
"name": "Quel est le traitement principal de la leucomalacie ?",
"position": 16,
"acceptedAnswer": {
"@type": "Answer",
"text": "Il n'existe pas de traitement spécifique, mais la rééducation et le soutien sont essentiels."
}
},
{
"@type": "Question",
"name": "La physiothérapie est-elle recommandée ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, la physiothérapie aide à améliorer la motricité et à réduire les complications."
}
},
{
"@type": "Question",
"name": "Des médicaments sont-ils utilisés ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des médicaments peuvent être prescrits pour gérer les symptômes comme les crises."
}
},
{
"@type": "Question",
"name": "Le suivi médical est-il nécessaire ?",
"position": 19,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, un suivi régulier est crucial pour évaluer le développement et ajuster les traitements."
}
},
{
"@type": "Question",
"name": "Y a-t-il des thérapies alternatives efficaces ?",
"position": 20,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines thérapies alternatives peuvent être bénéfiques, mais elles doivent être discutées avec un médecin."
}
},
{
"@type": "Question",
"name": "Quelles complications peuvent survenir ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les complications incluent des troubles moteurs, des problèmes cognitifs et des crises épileptiques."
}
},
{
"@type": "Question",
"name": "La leucomalacie entraîne-t-elle des handicaps ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, elle peut entraîner des handicaps permanents, affectant la qualité de vie de l'enfant."
}
},
{
"@type": "Question",
"name": "Y a-t-il un risque accru de troubles d'apprentissage ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les enfants peuvent présenter des troubles d'apprentissage en raison de lésions cérébrales."
}
},
{
"@type": "Question",
"name": "Les problèmes de vision sont-ils possibles ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des problèmes de vision peuvent survenir en raison de l'atteinte cérébrale."
}
},
{
"@type": "Question",
"name": "Les enfants atteints ont-ils besoin de soutien scolaire ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, un soutien scolaire adapté est souvent nécessaire pour aider à leur développement."
}
},
{
"@type": "Question",
"name": "Quels sont les principaux facteurs de risque ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les principaux facteurs incluent la prématurité, l'hypoxie et les infections néonatales."
}
},
{
"@type": "Question",
"name": "L'âge maternel influence-t-il le risque ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les grossesses chez les femmes plus jeunes ou plus âgées peuvent présenter des risques accrus."
}
},
{
"@type": "Question",
"name": "Les antécédents familiaux jouent-ils un rôle ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des antécédents familiaux de troubles neurologiques peuvent augmenter le risque."
}
},
{
"@type": "Question",
"name": "Les complications pendant l'accouchement sont-elles un facteur ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des complications comme l'hypoxie à la naissance peuvent contribuer au développement de la maladie."
}
},
{
"@type": "Question",
"name": "Les conditions de santé maternelles influencent-elles le risque ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des conditions comme le diabète ou l'hypertension peuvent augmenter le risque de leucomalacie."
}
}
]
}
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}
Department of Developmental Neuroscience, Laboratory of Vision, IRCCS Fondazione Stella Maris, Pisa, Italy; Department of Clinical and Experimental Medicine, University of Pisa, Italy.
Publications dans "Leucomalacie périventriculaire" :
1st Department of Pediatrics, Aghia Sofia Children's Hospital, National and Kapodistrian University of Athens, Thivon and Levadias, Athens, 11527, Greece.
Publications dans "Leucomalacie périventriculaire" :
Department of Neurology and Neurosurgery, Montreal Neurological Institute and Hospital, McGill University, 3801 University Street, Montreal, QC, H3A 2B4, Canada.
Publications dans "Leucomalacie périventriculaire" :
Patients with periventricular leukomalacia (PVL) have been reported to have a variety of complications; however, whether these involve impaired visual attention disabilities remains unclear. Therefore...
The study participants were 14 patients with PVL and seven controls with dyskinetic cerebral palsy. All participants performed three types of visual attention tasks: spatial attention tasks, feature-b...
The results revealed that patients with PVL often had visual attention disabilities, as indicated by a significant reduction in tasks requiring divided attention. Visual attention disabilities could b...
These findings suggest that family members and teachers of patients with PVL can easily screen for visual attention disabilities at home and school to improve mobility precautions in patients with thi...
Infantile epileptic spasms syndrome (IESS) with periventricular leukomalacia (PVL) has a poor neurological prognosis. Adrenocorticotropic hormone (ACTH) and vigabatrin therapies are the recommended fi...
We retrospectively examined 12 patients with IESS and PVL at Saitama Children's Medical Center between January 1993 and September 2022. We evaluated seizure outcomes 3 months post-ACTH therapy and at ...
The median onset age of epileptic spasms was 7 (range: 3-14) months. The median age at initiation of ACTH therapy was 9 (7-17) months. Seven of 12 patients (58.3%) showed a positive response. The medi...
Patients having epileptic discharge in the parietal or occipital regions on electroencephalography within 1-month post-ACTH therapy may be at a high risk of epileptic spasm recurrence or other seizure...
To survey the incidence of intraventricular hemorrhage (IVH) and periventricular leukomalacia (PVL) by gestational age and to report the impact on mortality and neurodevelopmental outcome in very pret...
This was a population-based cohort study of 1927 very preterm/very low birthweight infants born in 2014-2016 and admitted to Flemish neonatal intensive care units. Infants underwent standard follow-up...
No brain lesion was present in 31% of infants born at <26 weeks of gestation and 75.8% in infants born at 29-32 weeks of gestation. The prevalence of low-grade IVH/PVL (grades I and II) was 16.8% and ...
Both the prevalence and severity of IVH/PVL decreased significantly with advancing gestational age. More than 75% of all infants with low grades of IVH/PVL showed normal motor and cognitive outcome at...
Necrotizing enterocolitis (NEC) and periventricular leukomalacia (PVL) are relatively common conditions in premature infants with low birth weight (VLBW). However, in the current literature, there are...
Leukomalacia is a serious form of neonatal brain injury that often leads to neurodevelopmental impairment, and studies on neonatal leukomalacia and its long-term outcomes are lacking. The aim of this ...
Newborns diagnosed with leukomalacia by head magnetic resonance imaging (MRI) and who were admitted to intensive care units from January 2015 to June 2020 were enrolled. All infants were followed up t...
A total of 218 surviving infants with leukomalacia including 114 preterm infants and 104 term infants completed the follow-up. The major typesof leukomalacia on MRI were periventricular leukomalacia i...
Periventricular leukomalacia mainly occurred in preterm infants while subcortical cystic leukomalacia was commonly seen in term infants. Although the long-term neurodevelopmental outcomes of leukomala...
Intraventricular haemorrhage (IVH) and periventricular leukomalacia (PVL) in preterm infants are associated with an increased risk of long-term neurodevelopmental impairments (NDI) and cerebral palsy ...
This was a retrospective single-centre cohort study of preterm infants born at <29 weeks gestation or <1000 g birth weight who attended an Early Neurodevelopment Clinic at 3 to 4 months of corrected a...
Of 313 infants, 52.1% (n = 163), 41.2% (n = 129), 6.7% (n = 21) and 8.6% (n = 27) had no IVH, mild IVH, severe IVH and SBI, respectively. The adjusted odds of early CP/high-risk CP diagnosis were sign...
Preterm infants with severe IVH and SBI are at increased risk of early CP/high-risk of CP diagnosis at 3 to 4 months of corrected age....
Periventricular leukomalacia (PVL), a predominant form of brain injury in preterm survivors, is characterized by hypomyelination and microgliosis and is also the major cause of long-term neurobehavior...
Periventricular leukomalacia (PVL) is a common brain injury in premature infants, and epilepsy remains a significant complication. One concerning electroencephalographic (EEG) pattern found is develop...
This is a retrospective study of <36 weeks gestational age newborns who were followed in the neurodevelopmental clinic at Corewell Health East/Corewell Health Children's Hospital in Royal Oak, Michiga...
A total of 155 newborns met the inclusion criteria. Twenty-six patients had PVL. Nine patients had grade 2 to 3 PVL based on HUS review. EEG was performed on 15 patients with PVL at a mean age of 22 m...
EEG can help identify important abnormal electrographic patterns in premature infants with PVL early in life; this might give a window of opportunity to intervene early and improve long-term developme...
Recognizing and understanding the actions of others through motion information are vital functions for social adaptation. Conditions like neurological disorders and motor impairments can impact sensit...
Fetal inflammatory response syndrome (FIRS), the fetal equivalent of chorioamnionitis, is associated with poorer neonatal outcomes. FIRS is diagnosed through placental histology, namely by the identif...
We performed a retrospective cohort study at a level III neonatal intensive care unit (NICU), from January 1st 2008 to December 31st 2022, involving all inborn neonates with a gestational age below 30...
The study included 113 preterms, 27 (23.9%) of those had FCV and 86 (76.1%) did not. After adjusting to gestational age, prolonged rupture of membranes and preeclampsia, FCV was independently associat...
The authors identified an association between FIRS and the development of early-onset sepsis and cystic periventricular leukomalacia, highlighting the importance of early detection and management of t...
