Structural Characterization of Glycerol Kinase from the Thermophilic Fungus

ADP-dependent glucokinase ADPGK crystal structure glycerol glycerol kinase glycerol metabolism glycerol-3-phosphate

Journal

International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791

Informations de publication

Date de publication:
16 Dec 2020
Historique:
received: 02 11 2020
revised: 05 12 2020
accepted: 14 12 2020
entrez: 19 12 2020
pubmed: 20 12 2020
medline: 16 3 2021
Statut: epublish

Résumé

Glycerol is an organic compound that can be utilized as an alternative source of carbon by various organisms. One of the ways to assimilate glycerol by the cell is the phosphorylative catabolic pathway in which its activation is catalyzed by glycerol kinase (GK) and glycerol-3-phosphate (G3P) is formed. To date, several GK crystal structures from bacteria, archaea, and unicellular eukaryotic parasites have been solved. Herein, we present a series of crystal structures of GK from

Identifiants

pubmed: 33339113
pii: ijms21249570
doi: 10.3390/ijms21249570
pmc: PMC7765489
pii:
doi:

Substances chimiques

Fungal Proteins 0
Glycerol Kinase EC 2.7.1.30

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : Narodowe Centrum Nauki
ID : UMO-2015/19/D/NZ1/02009
Organisme : Fundacja na rzecz Nauki Polskiej
ID : TEAM TECH CORE FACILITY/2017-4/6
Organisme : Horizon 2020 Framework Programme
ID : 730872

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Auteurs

Piotr Wilk (P)

Malopolska Centre of Biotechnology, Jagiellonian University, 7a Gronostajowa St., 30-387 Kraków, Poland.

Katarzyna Kuśka (K)

Malopolska Centre of Biotechnology, Jagiellonian University, 7a Gronostajowa St., 30-387 Kraków, Poland.

Elżbieta Wątor (E)

Malopolska Centre of Biotechnology, Jagiellonian University, 7a Gronostajowa St., 30-387 Kraków, Poland.

Piotr H Małecki (PH)

International Institute of Molecular and Cell Biology in Warsaw, 4 Ksiecia Trojdena St., 02-109 Warszawa, Poland.

Klaudia Woś (K)

Malopolska Centre of Biotechnology, Jagiellonian University, 7a Gronostajowa St., 30-387 Kraków, Poland.

Piotr Tokarz (P)

Malopolska Centre of Biotechnology, Jagiellonian University, 7a Gronostajowa St., 30-387 Kraków, Poland.
Department of Biology, Institute of Molecular Biology & Biophysics, Eidgenössische Technische Hochschule Zürich, Otto-Stern-Weg 5, 8093 Zürich, Switzerland.

Grzegorz Dubin (G)

Malopolska Centre of Biotechnology, Jagiellonian University, 7a Gronostajowa St., 30-387 Kraków, Poland.

Przemysław Grudnik (P)

Malopolska Centre of Biotechnology, Jagiellonian University, 7a Gronostajowa St., 30-387 Kraków, Poland.

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Classifications MeSH