Outcomes after common arterial trunk repair: Impact of the surgical technique.
Atrial Appendage
/ diagnostic imaging
Cardiovascular Surgical Procedures
/ adverse effects
Child
Coronary Vessel Anomalies
/ epidemiology
France
/ epidemiology
Heart Ventricles
/ diagnostic imaging
Humans
Infant, Newborn
Male
Mortality
Outcome and Process Assessment, Health Care
Postoperative Complications
/ diagnosis
Reoperation
/ methods
Risk Adjustment
/ methods
Risk Factors
Truncus Arteriosus, Persistent
/ diagnosis
common arterial trunk
congenital heart defect
left atrial appendage
mortality
reintervention
right ventricle outflow tract
surgery
Journal
The Journal of thoracic and cardiovascular surgery
ISSN: 1097-685X
Titre abrégé: J Thorac Cardiovasc Surg
Pays: United States
ID NLM: 0376343
Informations de publication
Date de publication:
10 2021
10 2021
Historique:
received:
12
04
2020
revised:
21
10
2020
accepted:
22
10
2020
pubmed:
22
12
2020
medline:
1
10
2021
entrez:
21
12
2020
Statut:
ppublish
Résumé
We compared the risk of mortality and reintervention after common arterial trunk (CAT) repair for different surgical techniques, in particular the reconstruction of the right ventricle outflow tract with left atrial appendage (LAA) without a monocusp. The study population comprised 125 patients with repaired CAT who were followed-up at our institution between 2000 and 2018. Statistical analysis included Cox proportional hazard models. Median follow-up was 10.6 years. The 10-year survival rate was 88.2% (95% confidence interval [CI], 80.6-92.4) with the poorest outcome for CAT type IV (64.3%; 95% CI, 36.8-82.3; P < .01). In multivariable analysis, coronary anomalies (hazard ratio [HR], 11.63 [3.84-35.29], P < .001) and CAT with interrupted aortic arch (HR, 6.50 [2.10-20.16], P = .001) were substantial and independent risk factors for mortality. Initial repair with LAA was not associated with an increased risk of mortality (HR, 0.37 [0.11-1.24], P = .11). The median age at reintervention was 3.6 years [7.3 days-13.1 years]. At 10 years, freedom from reintervention was greater in the group with LAA repair compared with the valved conduit group, 73.3% (95% CI, 41.3-89.4) versus 17.2% (95% CI, 9.2-27.4) (P < .001), respectively. Using a valved conduit for repair (HR, 4.79 [2.45-9.39], P < .001), truncal valve insufficiency (HR, 2.92 [1.62-5.26], P < .001) and DiGeorge syndrome (HR, 2.01 [1.15-3.51], P = .01) were independent and clinically important risk factors for reintervention. For the repair of CAT, the LAA technique for right ventricle outflow tract reconstruction was associated with comparable survival and greater freedom from reintervention than the use of a valved conduit.
Identifiants
pubmed: 33342576
pii: S0022-5223(20)33136-6
doi: 10.1016/j.jtcvs.2020.10.147
pii:
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
1205-1214.e2Commentaires et corrections
Type : CommentIn
Type : CommentIn
Informations de copyright
Copyright © 2020 The American Association for Thoracic Surgery. Published by Elsevier Inc. All rights reserved.