Value of minimum intensity projections for chest CT in COVID-19 patients.


Journal

European journal of radiology
ISSN: 1872-7727
Titre abrégé: Eur J Radiol
Pays: Ireland
ID NLM: 8106411

Informations de publication

Date de publication:
Feb 2021
Historique:
received: 25 11 2020
accepted: 10 12 2020
pubmed: 29 12 2020
medline: 23 2 2021
entrez: 28 12 2020
Statut: ppublish

Résumé

To investigate whether minimum intensity projection (MinIP) reconstructions enable more accurate depiction of pulmonary ground-glass opacity (GGO) compared to standard transverse sections and multiplanar reformat (MPR) series in patients with suspected coronavirus disease 2019 (COVID-19). In this multinational study, chest CT scans of 185 patients were retrospectively analyzed. Diagnostic accuracy, diagnostic confidence, image quality regarding the assessment of GGO, as well as subjective time-efficiency of MinIP and standard MPR series were analyzed based on the assessment of six radiologists. In addition, the suitability for COVID-19 evaluation, image quality regarding GGO and subjective time-efficiency in clinical routine was assessed by five clinicians. The reference standard revealed a total of 149 CT scans with pulmonary GGO. MinIP reconstructions yielded significantly higher sensitivity (99.9 % vs 95.6 %), specificity (95.8 % vs 86.1 %) and accuracy (99.1 % vs 93.8 %) for assessing of GGO compared with standard MPR series. MinIP reconstructions achieved significantly higher ratings by radiologists concerning diagnostic confidence (medians, 5.00 vs 4.00), image quality (medians, 4.00 vs 4.00), contrast between GGO and unaffected lung parenchyma (medians, 5.00 vs 4.00) as well as subjective time-efficiency (medians, 5.00 vs 4.00) compared with MPR-series (all P < .001). Clinicians preferred MinIP reconstructions for COVID-19 assessment (medians, 5.00 vs 3.00), image quality regarding GGO (medians, 5.00 vs 3.00) and subjective time-efficiency in clinical routine (medians, 5.00 vs 3.00). MinIP reconstructions improve the assessment of COVID-19 in chest CT compared to standard images and may be suitable for routine application.

Identifiants

pubmed: 33360269
pii: S0720-048X(20)30668-9
doi: 10.1016/j.ejrad.2020.109478
pmc: PMC7831963
pii:
doi:

Types de publication

Journal Article Multicenter Study

Langues

eng

Sous-ensembles de citation

IM

Pagination

109478

Informations de copyright

Copyright © 2020 Elsevier B.V. All rights reserved.

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Auteurs

Christian Booz (C)

Division of Experimental Imaging, Department of Diagnostic and Interventional Radiology, University Hospital Frankfurt, Frankfurt am Main, Germany.

Thomas J Vogl (TJ)

Department of Diagnostic and Interventional Radiology, University Hospital Frankfurt, Frankfurt am Main, Germany.

U Joseph Schoepf (U)

Department of Radiology and Radiological Science, Medical University of South Carolina, Charleston, USA.

Damiano Caruso (D)

Department of Radiology and Radiological Science, Medical University of South Carolina, Charleston, USA; Department of Radiological Sciences, Oncology and Pathology, Sapienzia University of Rome, Rome, Italy.

Maria Cristina Inserra (MC)

Department of Radiology, University Hospital Vittorio Emanuele Catania, Catania, Italy.

Ibrahim Yel (I)

Division of Experimental Imaging, Department of Diagnostic and Interventional Radiology, University Hospital Frankfurt, Frankfurt am Main, Germany.

Simon S Martin (SS)

Division of Experimental Imaging, Department of Diagnostic and Interventional Radiology, University Hospital Frankfurt, Frankfurt am Main, Germany; Department of Radiology and Radiological Science, Medical University of South Carolina, Charleston, USA.

Andreas M Bucher (AM)

Department of Diagnostic and Interventional Radiology, University Hospital Frankfurt, Frankfurt am Main, Germany; Department of Radiology and Radiological Science, Medical University of South Carolina, Charleston, USA.

Lukas Lenga (L)

Division of Experimental Imaging, Department of Diagnostic and Interventional Radiology, University Hospital Frankfurt, Frankfurt am Main, Germany.

Danilo Caudo (D)

Division of Experimental Imaging, Department of Diagnostic and Interventional Radiology, University Hospital Frankfurt, Frankfurt am Main, Germany; Department of Biomedical Sciences and Morphological and Functional Imaging, University of Messina, Messina, Italy.

Teresa Schreckenbach (T)

Department of General and Visceral Surgery, University Hospital Frankfurt, Frankfurt am Main, Germany.

Niklas Schoell (N)

Department of Pneumonology, University Hospital Frankfurt, Frankfurt am Main, Germany.

Christian Huegel (C)

Department of Pneumonology, University Hospital Frankfurt, Frankfurt am Main, Germany.

Jan Stratmann (J)

Department of Hematology and Oncology, University Hospital Frankfurt, Frankfurt am Main, Germany.

Mariuca Vasa-Nicotera (M)

Department of Cardiology, University Hospital Frankfurt, Frankfurt am Main, Germany.

Daniel E Rachovitsky-Duarte (DE)

Oxford Internet Institute, University of Oxford, Oxford, England, United Kingdom.

Andrea Laghi (A)

Department of Radiological Sciences, Oncology and Pathology, Sapienzia University of Rome, Rome, Italy.

Domenico De Santis (D)

Department of Radiology and Radiological Science, Medical University of South Carolina, Charleston, USA; Department of Radiological Sciences, Oncology and Pathology, Sapienzia University of Rome, Rome, Italy.

Silvio Mazziotti (S)

Department of Biomedical Sciences and Morphological and Functional Imaging, University of Messina, Messina, Italy.

Tommaso D'Angelo (T)

Department of Biomedical Sciences and Morphological and Functional Imaging, University of Messina, Messina, Italy; Department of Radiology, University Hospital Vittorio Emanuele Catania, Catania, Italy.

Moritz H Albrecht (MH)

Division of Experimental Imaging, Department of Diagnostic and Interventional Radiology, University Hospital Frankfurt, Frankfurt am Main, Germany; Department of Radiology and Radiological Science, Medical University of South Carolina, Charleston, USA. Electronic address: experimentalimaging@gmail.com.

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