Whole genome CRISPR screening identifies TOP2B as a potential target for IMiD sensitization in multiple myeloma.

Clustered Regularly Interspaced Short Palindromic Repeats Humans Immunologic Factors Multiple Myeloma / drug therapy

Journal

Haematologica
ISSN: 1592-8721
Titre abrégé: Haematologica
Pays: Italy
ID NLM: 0417435

Informations de publication

Date de publication:
01 07 2021
Historique:
aheadofprint: 30 12 2020
received: 03 07 2020
entrez: 30 12 2020
pubmed: 31 12 2020
medline: 28 5 2021
Statut: epublish

Résumé

Not available.

Identifiants

DOI: 10.3324/haematol.2020.265611 PMID: 33375771 PMC: PMC8252923
pubmed: 33375771
doi: 10.3324/haematol.2020.265611
pmc: PMC8252923
doi:

Substances chimiques

Immunologic Factors 0

Types de publication

Letter

Langues

eng

Sous-ensembles de citation

IM

Pagination

2013-2017

Références

Cell. 2011 Nov 23;147(5):1024-39
pubmed: 22118460
Blood. 2008 Mar 1;111(5):2516-20
pubmed: 17975015
Science. 2014 Jan 17;343(6168):301-5
pubmed: 24292625
Blood. 2011 Nov 3;118(18):4771-9
pubmed: 21860026
Science. 2014 Jan 17;343(6168):305-9
pubmed: 24292623
Cancer Res. 2007 Sep 15;67(18):8839-46
pubmed: 17875725
Cell Rep. 2016 May 17;15(7):1554-1565
pubmed: 27160905
Elife. 2018 Jun 18;7:
pubmed: 29911972
Crit Rev Biochem Mol Biol. 2013 Nov-Dec;48(6):575-608
pubmed: 24088064
Cancer Cell. 2014 Jan 13;25(1):9-11
pubmed: 24434206
J Clin Pharmacol. 2011 May;51(5):731-8
pubmed: 20484616
PLoS One. 2017 Jan 3;12(1):e0169338
pubmed: 28046085
Annu Rev Biochem. 2013;82:139-70
pubmed: 23495937
Leukemia. 2019 Jan;33(1):171-180
pubmed: 30026574
Blood. 2018 Sep 20;132(12):1293-1303
pubmed: 30042095

Auteurs

Matteo Costacurta (M)

Translational Haematology Program, Peter MacCallum Cancer Centre, Melbourne; Sir Peter MacCallum Department of Oncology, The University of Melbourne.

Stephin J Vervoort (SJ)

Translational Haematology Program, Peter MacCallum Cancer Centre, Melbourne; Sir Peter MacCallum Department of Oncology, The University of Melbourne.

Simon J Hogg (SJ)

Translational Haematology Program, Peter MacCallum Cancer Centre, Melbourne; Sir Peter MacCallum Department of Oncology, The University of Melbourne.

Benjamin P Martin (BP)

Translational Haematology Program, Peter MacCallum Cancer Centre, Melbourne; Sir Peter MacCallum Department of Oncology, The University of Melbourne.

Ricky W Johnstone (RW)

Translational Haematology Program, Peter MacCallum Cancer Centre, Melbourne; Sir Peter MacCallum Department of Oncology, The University of Melbourne. ricky.johnstone@petermac.org.

Jake Shortt (J)

Translational Haematology Program, Peter MacCallum Cancer Centre, Melbourne; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville; Monash Haematology, Monash Health, Clayton; Blood Cancer Therapeutics Laboratory, School of Clinical Sciences at Monash Health, Monash University, Clayton. jake.shortt@monash.edu.

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Classifications MeSH

questionsmedicales.fr › Phénomènes génétiques › Structures génétiques › Génome › Composants de génome › Séquences répétées en tandem › Clustered regularly interspaced short palindromic repeats › Whole genome CRISPR screening identifies TOP2B...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Whole genome CRISPR screening identifies TOP2B...
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Effets physiologiques des médicaments › Facteurs immunologiques › Whole genome CRISPR screening identifies TOP2B...
questionsmedicales.fr › Maladies du système immunitaire › Syndromes immunoprolifératifs › Paraprotéinémies › Myélome multiple › Whole genome CRISPR screening identifies TOP2B...