Mass screening for neuroblastoma in infants.

Biomarkers, Tumor / metabolism Early Detection of Cancer / methods Homovanillic Acid / metabolism Humans Incidence Infant Infant Mortality Mass Screening / legislation & jurisprudence Neuroblastoma / diagnosis Vanilmandelic Acid / metabolism

Journal

Discovery medicine
ISSN: 1944-7930
Titre abrégé: Discov Med
Pays: United States
ID NLM: 101250006

Informations de publication

Date de publication:
Historique:
entrez: 31 12 2020
pubmed: 1 1 2021
medline: 28 9 2021
Statut: ppublish

Résumé

Neuroblastoma (NB) is the only pediatric tumor that is screened for nationwide by detecting the urinary levels of homovanillic acid and/or vanillylmandelic acid; however, whether NB screening reduces the mortality rate has not been established. This review compared the incidence and mortality rates among data from international mass screening for NB, as well as an analysis of differences in age of screening, detection methods, and diagnostic biomarkers. A well-designed trial exploring possible benefits and hazards is warranted prior to resuming mass screening for NB.

Identifiants

PMID: 33382962
pubmed: 33382962

Substances chimiques

Biomarkers, Tumor 0
Vanilmandelic Acid 55-10-7
Homovanillic Acid X77S6GMS36

Types de publication

Journal Article Research Support, Non-U.S. Gov't Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

63-70

Auteurs

Meng Wei (M)

Department of Pediatric Surgery, Children's Hospital of Fudan University, Shanghai 201102, China.

Mujie Ye (M)

Department of Pediatric Surgery, Children's Hospital of Fudan University, Shanghai 201102, China.

Kuiran Dong (K)

Department of Pediatric Surgery, Children's Hospital of Fudan University, Shanghai 201102, China.
Corresponding author.

Rui Dong (R)

Department of Pediatric Surgery, Children's Hospital of Fudan University, Shanghai 201102, China.
Corresponding author.

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Classifications MeSH

questionsmedicales.fr › Facteurs biologiques › Marqueurs biologiques › Marqueurs biologiques tumoraux › Mass screening for neuroblastoma in infants.
questionsmedicales.fr › Diagnostic › Diagnostic précoce › Dépistage précoce du cancer › Mass screening for neuroblastoma in infants.
questionsmedicales.fr › Composés chimiques organiques › Acides carboxyliques › Acides carbocycliques › Phénylacétates › Acide homovanillique › Mass screening for neuroblastoma in infants.
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Mass screening for neuroblastoma in infants.
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Collecte de données › Registre civil › Morbidité › Incidence › Mass screening for neuroblastoma in infants.
questionsmedicales.fr › Personnes › Tranches d'âge › Nourrisson › Mass screening for neuroblastoma in infants.
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Collecte de données › Registre civil › Mortalité › Mortalité infantile › Mass screening for neuroblastoma in infants.
questionsmedicales.fr › Environnement et santé publique › Santé publique › Pratiques en santé publique › Dépistage de masse › Mass screening for neuroblastoma in infants.
questionsmedicales.fr › Tumeurs › Tumeurs par type histologique › Tumeurs du tissu nerveux › Tumeurs neuroectodermiques › Tumeurs neuroépitheliales › Tumeurs neuroectodermiques primitives › Tumeurs neuroectodermiques primitives périphériques › Neuroblastome › Mass screening for neuroblastoma in infants.
questionsmedicales.fr › Composés chimiques organiques › Acides carboxyliques › Hydroxyacides › Acides mandéliques › Acide vanilmandélique › Mass screening for neuroblastoma in infants.