Exosomal miRNAs as Potential Biomarkers to Monitor Phosphodiesterase 5 Inhibitor Induced Anti-Fibrotic Effects on CCl
CCl4
PDE 5 inhibitor
exosomes
gene expression
liver fibrosis
microRNAs
Journal
International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791
Informations de publication
Date de publication:
31 Dec 2020
31 Dec 2020
Historique:
received:
28
11
2020
revised:
16
12
2020
accepted:
29
12
2020
entrez:
5
1
2021
pubmed:
6
1
2021
medline:
7
4
2021
Statut:
epublish
Résumé
MicroRNAs (miRNAs) are short, non-coding RNA species that are important post-transcriptional regulators of gene expression and play an important role in the pathogenesis of non-alcoholic fatty liver disease. Here, we investigated the phosphodiesterase 5 (PDE5) inhibitor induced effects on hepatic and plasma exosomal miRNA expression in CCl
Identifiants
pubmed: 33396535
pii: ijms22010382
doi: 10.3390/ijms22010382
pmc: PMC7795540
pii:
doi:
Substances chimiques
Biomarkers
0
MicroRNAs
0
Phosphodiesterase 5 Inhibitors
0
Carbon Tetrachloride
CL2T97X0V0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
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