Late post-natal neurometabolic development in healthy male rats using


Journal

Journal of neurochemistry
ISSN: 1471-4159
Titre abrégé: J Neurochem
Pays: England
ID NLM: 2985190R

Informations de publication

Date de publication:
05 2021
Historique:
revised: 01 01 2020
received: 11 10 2018
accepted: 25 12 2020
pubmed: 10 1 2021
medline: 22 6 2021
entrez: 9 1 2021
Statut: ppublish

Résumé

Brain metabolism evolves rapidly during early post-natal development in the rat. While changes in amino acids, energy metabolites, antioxidants or metabolites involved in phospholipid metabolism have been reported in the early stages, neurometabolic changes during the later post-natal period are less well characterized. Therefore, we aimed to assess the neurometabolic changes in male Wistar rats between post-natal days 29 and 77 (p29-p77) using longitudinal magnetic resonance spectroscopy (MRS) in vivo at 9.4 Tesla.

Identifiants

pubmed: 33421129
doi: 10.1111/jnc.15294
doi:

Substances chimiques

Anesthetics, Inhalation 0
Phosphorus Isotopes 0
Protons 0
Taurine 1EQV5MLY3D
Glutamic Acid 3KX376GY7L
Inositol 4L6452S749
Isoflurane CYS9AKD70P
Choline N91BDP6H0X

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

508-519

Informations de copyright

© 2021 International Society for Neurochemistry.

Références

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Auteurs

Veronika Račkayová (V)

CIBM Center for Biomedical Imaging, Lausanne, Switzerland.
Animal Imaging and Technology, Ecole Polytechnique Federale de Lausanne (EPFL), Lausanne, Switzerland.
Laboratory of Functional and Metabolic Imaging (LIFMET), Ecole Polytechnique Federale de Lausanne (EPFL), Lausanne, Switzerland.

Dunja Simicic (D)

CIBM Center for Biomedical Imaging, Lausanne, Switzerland.
Animal Imaging and Technology, Ecole Polytechnique Federale de Lausanne (EPFL), Lausanne, Switzerland.
Laboratory of Functional and Metabolic Imaging (LIFMET), Ecole Polytechnique Federale de Lausanne (EPFL), Lausanne, Switzerland.

Guillaume Donati (G)

Laboratory of Functional and Metabolic Imaging (LIFMET), Ecole Polytechnique Federale de Lausanne (EPFL), Lausanne, Switzerland.

Olivier Braissant (O)

Service of Clinical Chemistry, University of Lausanne and University Hospital of Lausanne, Lausanne, Switzerland.

Rolf Gruetter (R)

Laboratory of Functional and Metabolic Imaging (LIFMET), Ecole Polytechnique Federale de Lausanne (EPFL), Lausanne, Switzerland.

Valérie A McLin (VA)

Swiss Pediatric Liver Center, University Hospitals Geneva, Geneva, Switzerland.
Department of Pediatrics, Gynecology, and Obstetrics, University of Geneva Medical School, Geneva, Switzerland.

Cristina Cudalbu (C)

CIBM Center for Biomedical Imaging, Lausanne, Switzerland.
Animal Imaging and Technology, Ecole Polytechnique Federale de Lausanne (EPFL), Lausanne, Switzerland.

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