New Pd-Fe ferrocenyl antiparasitic compounds with bioactive 8-hydroxyquinoline ligands: a comparative study with their Pt-Fe analogues.

Antiparasitic Agents / chemistry Ferrous Compounds / chemistry Iron / chemistry Ligands Metallocenes / chemistry Oxyquinoline / chemistry Palladium / chemistry Quantitative Structure-Activity Relationship

Journal

Dalton transactions (Cambridge, England : 2003)
ISSN: 1477-9234
Titre abrégé: Dalton Trans
Pays: England
ID NLM: 101176026

Informations de publication

Date de publication:
07 Feb 2021
Historique:
pubmed: 16 1 2021
medline: 5 10 2021
entrez: 15 1 2021
Statut: ppublish

Résumé

In the search for a more effective chemotherapy for the treatment of Human African Trypanosomiasis, a disease caused by the parasite Trypanosoma brucei, the development of ferrocenyl compounds has arisen as a promising strategy. In this work, five new Pd-Fe heterobimetallic [Pd

Identifiants

DOI: 10.1039/d0dt03963b PMID: 33449983
pubmed: 33449983
doi: 10.1039/d0dt03963b
doi:

Substances chimiques

Antiparasitic Agents 0
Ferrous Compounds 0
Ligands 0
Metallocenes 0
Palladium 5TWQ1V240M
Oxyquinoline 5UTX5635HP
Iron E1UOL152H7
ferrocene U96PKG90JQ

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1651-1665

Auteurs

Feriannys Rivas (F)

Área Química Inorgánica, Programa de Posgrados, Facultad de Química, Universidad de la República, Gral. Flores 2124, 11800 Montevideo, Uruguay. dgambino@fq.edu.uy.

Andrea Medeiros (A)

Cristina Quiroga (C)

Diego Benítez (D)

Marcelo Comini (M)

Esteban Rodríguez-Arce (E)

Ignacio Machado (I)

Hugo Cerecetto (H)

Dinorah Gambino (D)

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Classifications MeSH

questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Anti-infectieux › Antiparasitaires › New Pd-Fe ferrocenyl antiparasitic compounds...
questionsmedicales.fr › Produits chimiques inorganiques › Composés du fer › Composés du fer II › New Pd-Fe ferrocenyl antiparasitic compounds...
questionsmedicales.fr › Produits chimiques inorganiques › Métaux › Métaux lourds › Fer › New Pd-Fe ferrocenyl antiparasitic compounds...
questionsmedicales.fr › Actions chimiques et utilisations › Utilisations spécialisées de produits chimiques › Produits chimiques de laboratoire › Ligands › New Pd-Fe ferrocenyl antiparasitic compounds...
questionsmedicales.fr › Composés chimiques organiques › Composés organométalliques › Métallocènes › New Pd-Fe ferrocenyl antiparasitic compounds...
questionsmedicales.fr › Composés hétérocycliques › Composés hétérocycliques à cycles fusionnés › Composés hétérobicycliques › Quinoléines › Hydroxyquinoléines › Hydroxy-8 quinoléine › New Pd-Fe ferrocenyl antiparasitic compounds...
questionsmedicales.fr › Produits chimiques inorganiques › Métaux › Métaux lourds › Palladium › New Pd-Fe ferrocenyl antiparasitic compounds...
questionsmedicales.fr › Phénomènes physiologiques › Phénomènes pharmacologiques et toxicologiques › Phénomènes pharmacologiques › Relation structure-activité › Relation quantitative structure-activité › New Pd-Fe ferrocenyl antiparasitic compounds...