Norovirus strains in patients with acute gastroenteritis in rural and low-income urban areas in northern Brazil.
Base Sequence
Brazil
/ epidemiology
Caliciviridae Infections
/ epidemiology
Cross-Sectional Studies
Feces
/ virology
Gastroenteritis
/ epidemiology
Genetic Variation
/ genetics
Genotype
High-Throughput Nucleotide Sequencing
Humans
Molecular Epidemiology
Norovirus
/ classification
Phylogeny
Poverty
/ statistics & numerical data
RNA, Viral
/ genetics
Journal
Archives of virology
ISSN: 1432-8798
Titre abrégé: Arch Virol
Pays: Austria
ID NLM: 7506870
Informations de publication
Date de publication:
Mar 2021
Mar 2021
Historique:
received:
09
08
2020
accepted:
13
11
2020
pubmed:
20
1
2021
medline:
24
2
2021
entrez:
19
1
2021
Statut:
ppublish
Résumé
From 2010-2016, a total of 251 stool samples were screened for norovirus using next-generation sequencing (NGS) followed by phylogenetic analysis to investigate the genotypic diversity of noroviruses in rural and low-income urban areas in northern Brazil. Norovirus infection was detected in 19.9% (50/251) of the samples. Eight different genotypes were identified: GII.4_Sydney[P31] (64%, 32/50), GII.6[P7] (14%, 7/50), GII.17[P17] (6%, 3/50), GII.1[P33] (6%, 3/50), GII.3[P16] (4%, 2/50), GII.2[P16] (2%, 1/50), GII.2[P2] (2%, 1/50), and GII.4_New Orleans[P4] (2%, 1/50). Distinct GII.6[P7] variants were recognized, indicating the presence of different co-circulating strains. Elucidating norovirus genetic diversity will improve our understanding of their potential health burden, in particular for the GII.4_Sydney[P31] variant.
Identifiants
pubmed: 33462673
doi: 10.1007/s00705-020-04944-5
pii: 10.1007/s00705-020-04944-5
doi:
Substances chimiques
RNA, Viral
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
905-913Subventions
Organisme : Fundação de Amparo à Pesquisa do Estado de São Paulo (BR)
ID : 2016/01735-2
Organisme : Fundação de Amparo à Pesquisa do Estado de São Paulo (BR)
ID : 2017/00021-9
Organisme : Fundação de Amparo à Pesquisa do Estado de São Paulo (BR)
ID : 2015/12944-9
Organisme : Fundação de Amparo à Pesquisa do Estado de São Paulo (BR)
ID : 2019/21706-5
Organisme : Conselho Nacional de Desenvolvimento Científico e Tecnológico (BR)
ID : 400354/2016-0
Organisme : Conselho Nacional de Desenvolvimento Científico e Tecnológico (BR)
ID : 302677/2019-4
Références
Atmar RL (2010) Noroviruses—state of the art. Food Environ Virol 2(3):117–126. https://doi.org/10.1007/s12560-010-9038-1
doi: 10.1007/s12560-010-9038-1
pubmed: 20814448
pmcid: 2929844
Glass PJ, White LJ, Ball JM et al (2000) Norwalk virus open reading frame 3 encodes a minor structural protein. J Virol 74(14):6581–6591. https://doi.org/10.1128/jvi.74.14.6581-6591.2000
doi: 10.1128/jvi.74.14.6581-6591.2000
pubmed: 10864672
pmcid: 112168
Kroneman A, Vennema H, Deforche K et al (2011) An automated genotyping tool for enteroviruses and noroviruses. J Clin Virol 51(2):121–125. https://doi.org/10.1016/j.jcv.2011.03.006
doi: 10.1016/j.jcv.2011.03.006
pubmed: 21514213
Chhabra P, de Graaf M, Parra GI et al (2019) Updated classification of norovirus genogroups and genotypes. J Gen Virol 100(10):1393–1406. https://doi.org/10.1099/jgv.0.001318 . Corrigendum: Updated classification of norovirus genogroups and genotypes. J Gen Virol 2020;101(8):893. https://doi.org/10.1099/jgv.0.001475
Matsushima Y, Ishikawa M, Shimizu T et al (2015) Genetic analyses of GII.17 norovirus strains in diarrheal disease outbreaks from December 2014 to March 2015 in Japan reveal a novel polymerase sequence and amino acid substitutions in the capsid region. Euro Surveill 20(26):21173. https://doi.org/10.2807/1560-7917.es2015.20.26.21173
doi: 10.2807/1560-7917.es2015.20.26.21173
pubmed: 26159307
Siqueira JAM, Bandeira RDS, Oliveira DS et al (2017) Genotype diversity and molecular evolution of noroviruses: A 30-year (1982–2011) comprehensive study with children from Northern Brazil. PLoS ONE 12(6):e0178909. https://doi.org/10.1371/journal.pone.0178909
doi: 10.1371/journal.pone.0178909
pubmed: 28604828
pmcid: 5467842
Parra GI, Green KY (2015) Genome of emerging norovirus GII.17, United States, 2014. Emerg Infect Dis 21(8):1477–1479. https://doi.org/10.3201/eid2108.150652
doi: 10.3201/eid2108.150652
pubmed: 26196235
pmcid: 4517714
Eden JS, Hewitt J, Lim KL et al (2014) The emergence and evolution of the novel epidemic norovirus GII.4 variant Sydney 2012. Virology 450–451:106–113. https://doi.org/10.1016/j.virol.2013.12.005
doi: 10.1016/j.virol.2013.12.005
pubmed: 24503072
Hoa Tran TN, Trainor E, Nakagomi T et al (2013) Molecular epidemiology of noroviruses associated with acute sporadic gastroenteritis in children: global distribution of genogroups, genotypes and GII.4 variants. J Clin Virol 56(3):185–193. https://doi.org/10.1016/j.jcv.2012.11.011
doi: 10.1016/j.jcv.2012.11.011
pubmed: 23218993
Parra GI, Squires RB, Karangwa CK et al (2017) Static and evolving norovirus genotypes: implications for epidemiology and immunity. PLoS Pathog. 13(1):e1006136. https://doi.org/10.1371/journal.ppat.1006136
doi: 10.1371/journal.ppat.1006136
pubmed: 28103318
pmcid: 5283768
van Beek J, Ambert-Balay K, Botteldoorn N et al (2013) Indications for worldwide increased norovirus activity associated with emergence of a new variant of genotype II.4, late 2012. Euro Surveill 18(1):8–9
pubmed: 23305715
Lu J, Sun L, Fang L et al (2015) Gastroenteritis outbreaks caused by norovirus GII.17, Guangdong Province, China, 2014–2015. Emerg Infect Dis 21(7):1240–1242. https://doi.org/10.3201/eid2107.150226
doi: 10.3201/eid2107.150226
pubmed: 26080037
pmcid: 4480401
Andrade JSR, Fumian TM, Leite JPG et al (2017) Detection and molecular characterization of emergent GII.P17/GII.17 Norovirus in Brazil, 2015. Infect Genet Evol 51:28–32. https://doi.org/10.1016/j.meegid.2017.03.011
doi: 10.1016/j.meegid.2017.03.011
pubmed: 28300648
Lun JH, Hewitt J, Sitabkhan A et al (2018) Emerging recombinant noroviruses identified by clinical and waste water screening. Emerg Microbes Infect 7(1):50. https://doi.org/10.1038/s41426-018-0047-8
doi: 10.1038/s41426-018-0047-8
pubmed: 29593246
pmcid: 5874246
Medici MC, Tummolo F, Calderaro A et al (2015) Identification of the novel Kawasaki 2014 GII.17 human norovirus strain in Italy, 2015. Euro Surveill 20(35):30010. https://doi.org/10.2807/1560-7917.ES.2015.20.35.30010
doi: 10.2807/1560-7917.ES.2015.20.35.30010
pubmed: 26530698
Mattison CP, Cardemil CV, Hall AJ (2018) Progress on norovirus vaccine research: public health considerations and future directions. Expert Rev Vaccines 17(9):773–784. https://doi.org/10.1080/14760584.2018.1510327
doi: 10.1080/14760584.2018.1510327
pubmed: 30092671
pmcid: 6410563
Barreira DMPG, Fumian TM, Tonini MAL et al (2017) Detection and molecular characterization of the novel recombinant norovirus GII.P16-GII.4 Sydney in southeastern Brazil in 2016. PLoS ONE 12(12):e0189504. https://doi.org/10.1371/journal.pone.0189504
doi: 10.1371/journal.pone.0189504
pubmed: 29236779
pmcid: 5728567
Fioretti JM, Fumian TM, Rocha MS et al (2018) Surveillance of noroviruses in Rio De Janeiro, Brazil: occurrence of new GIV genotype in clinical and wastewater samples. Food Environ Virol 10(1):1–6. https://doi.org/10.1007/s12560-017-9308-2
doi: 10.1007/s12560-017-9308-2
pubmed: 28639212
Hernandez JM, Silva LD, Junior ECS et al (2018) Molecular epidemiology and temporal evolution of norovirus associated with acute gastroenteritis in Amazonas state, Brazil. BMC Infect Dis. 18(1):147. https://doi.org/10.1186/s12879-018-3068-y
doi: 10.1186/s12879-018-3068-y
pubmed: 29606095
pmcid: 5879549
Gondim RDG, Pankov RC, Prata MMG et al (2018) Genetic diversity of norovirus infections, coinfections, and undernutrition in children from Brazilian Semiarid Region. J Pediatr Gastroenterol Nutr 67(6):e117–e122. https://doi.org/10.1097/MPG.0000000000002085
doi: 10.1097/MPG.0000000000002085
pubmed: 29985875
Cantelli CP, da Silva MFM, Fumian TM et al (2019) High genetic diversity of noroviruses in children from a community-based study in Rio de Janeiro, Brazil, 2014–2018. Arch Virol. 164(5):1427–1432. https://doi.org/10.1007/s00705-019-04195-z
doi: 10.1007/s00705-019-04195-z
pubmed: 30859473
Dábilla N, Almeida TNV, Franco FC et al (2019) Recombinant noroviruses detected in Mid-West region of Brazil in two different periods 2009–2011 and 2014–2015: atypical breakpoints of recombination and detection of distinct GII.P7-GII.6 lineages. Infect Genet Evol 68:47–53. https://doi.org/10.1016/j.meegid.2018.12.007
doi: 10.1016/j.meegid.2018.12.007
pubmed: 30529559
Tahmasebi R, Luchs A, Tardy K, Hefford PM, Tinker RJ, Eilami O et al (2020) Viral gastroenteritis in Tocantins, Brazil: characterizing the diversity of human adenovirus F through next-generation sequencing and bioinformatics. J Gen Virol. https://doi.org/10.1099/jgv.0.001500 ((epub ahead of print))
doi: 10.1099/jgv.0.001500
pubmed: 33044150
Watanabe ASA, Luchs A, Leal É et al (2018) Complete genome sequences of six human bocavirus strains from patients with acute gastroenteritis in the North Region of Brazil. Genome Announc 6(17):e00235-e318. https://doi.org/10.1128/genomeA.00235-18
doi: 10.1128/genomeA.00235-18
pubmed: 29700140
pmcid: 5920168
Cilli A, Luchs A, Leal E et al (2019) Human sapovirus GI2 and GI3 from children with acute gastroenteritis in northern Brazil. Mem Inst Oswaldo Cruz 114:e180574. https://doi.org/10.1590/0074-02760180574
doi: 10.1590/0074-02760180574
pubmed: 30970051
pmcid: 6452520
Ribeiro GO, Luchs A, Milagres FAP et al (2018) Detection and characterization of enterovirus B73 from a child in Brazil. Viruses 11(1):16. https://doi.org/10.3390/v11010016
doi: 10.3390/v11010016
pmcid: 6357135
Luchs A, Leal E, Tardy K et al (2019) The rare enterovirus c99 and echovirus 29 strains in Brazil: potential risks associated to silent circulation. Mem Inst Oswaldo Cruz 114:e190160. https://doi.org/10.1590/0074-02760190160
doi: 10.1590/0074-02760190160
pubmed: 31411312
pmcid: 6690645
Rosa UA, Ribeiro GO, Villanova F et al (2019) First identification of mammalian orthoreovirus type 3 by gut virome analysis in diarrheic child in Brazil. Sci Rep 9(1):18599. https://doi.org/10.1038/s41598-019-55216-5
doi: 10.1038/s41598-019-55216-5
pubmed: 31819139
pmcid: 6901473
da Costa AC, Luchs A, Milagres FAP et al (2018) Near full length genome of a recombinant (E/D) cosavirus strain from a rural area in the central region of Brazil. Sci Rep 8(1):12304. https://doi.org/10.1038/s41598-018-30214-1
doi: 10.1038/s41598-018-30214-1
pubmed: 30120342
pmcid: 6098101
da Costa AC, Luchs A, Milagres FAP et al (2018) Recombination located over 2A–2B junction ribosome frameshifting region of saffold cardiovirus. Viruses 10(10):520. https://doi.org/10.3390/v10100520
doi: 10.3390/v10100520
pmcid: 6213509
Luchs A, Leal E, Komninakis SV et al (2018) Wuhan large pig roundworm virus identified in human feces in Brazil. Virus Genes 54(3):470–473. https://doi.org/10.1007/s11262-018-1557-0
doi: 10.1007/s11262-018-1557-0
pubmed: 29594920
Leal É, Luchs A, Milagres FAP et al (2019) Recombinant strains of human parechovirus in rural areas in the North of Brazil. Viruses 11(6):488. https://doi.org/10.3390/v11060488
doi: 10.3390/v11060488
pmcid: 6630568
da Costa AC, Leal E, Gill D et al (2019) Discovery of Cucumis melo endornavirus by deep sequencing of human stool samples in Brazil. Virus Genes 55(3):332–338. https://doi.org/10.1007/s11262-019-01648-0
doi: 10.1007/s11262-019-01648-0
pubmed: 30915664
Tahmasebi R, Costa ACD, Tardy K et al (2020) Genomic analyses of potential novel recombinant human adenovirus C in Brazil. Viruses 12(5):508. https://doi.org/10.3390/v12050508
doi: 10.3390/v12050508
pmcid: 7290489
Li L, Deng X, Mee ET et al (2015) Comparing viral metagenomics methods using a highly multiplexed human viral pathogens reagent. J Virol Methods 213:139–146. https://doi.org/10.1016/j.jviromet.2014.12.002
doi: 10.1016/j.jviromet.2014.12.002
pubmed: 25497414
Charlys da Costa A, Thézé J, Komninakis SCV et al (2017) Spread of Chikungunya Virus East/Central/South African Genotype in Northeast Brazil. Emerg Infect Dis 23(10):1742–1744. https://doi.org/10.3201/eid2310.170307
doi: 10.3201/eid2310.170307
pubmed: 28930031
pmcid: 5621546
Deng X, Naccache SN, Ng T et al (2015) An ensemble strategy that significantly improves de novo assembly of microbial genomes from metagenomic next-generation sequencing data. Nucleic Acids Res 43(7):e46. https://doi.org/10.1093/nar/gkv002
doi: 10.1093/nar/gkv002
pubmed: 25586223
pmcid: 4402509
Altan E, Delaney MA, Colegrove KM et al (2020) Complex virome in a mesenteric lymph node from a Californian Sea Lion (Zalophus californianus) with polyserositis and steatitis. Viruses 12(8):E793. https://doi.org/10.3390/v12080793
doi: 10.3390/v12080793
pubmed: 32718049
Ng TF, Marine R, Wang C et al (2012) High variety of known and new RNA and DNA viruses of diverse origins in untreated sewage. J Virol 86(22):12161–12175. https://doi.org/10.1128/JVI.00869-12
doi: 10.1128/JVI.00869-12
pubmed: 22933275
pmcid: 3486453
Larkin MA, Blackshields G, Brown NP et al (2007) Clustal W and Clustal X version 2.0. Bioinformatics 23(21):2947–2948. https://doi.org/10.1093/bioinformatics/btm404
doi: 10.1093/bioinformatics/btm404
pubmed: 17846036
Kumar S, Stecher G, Tamura K (2016) MEGA7: molecular evolutionary genetics analysis version 7.0 for bigger datasets. Mol Biol Evol 33(7):1870–1874. https://doi.org/10.1093/molbev/msw054
doi: 10.1093/molbev/msw054
pubmed: 27004904
pmcid: 8210823
Fu JG, Ai J, Zhang J et al (2016) Molecular epidemiology of genogroup II norovirus infection among hospitalized children with acute gastroenteritis in Suzhou (Jiangsu, China) from 2010 to 2013. J Med Virol 88(6):954–960. https://doi.org/10.1002/jmv.24429
doi: 10.1002/jmv.24429
pubmed: 26547266
Xue Y, Pan H, Hu J et al (2015) Epidemiology of norovirus infections among diarrhea outpatients in a diarrhea surveillance system in Shanghai, China: a cross-sectional study. BMC Infect Dis 15:183. https://doi.org/10.1186/s12879-015-0922-z
doi: 10.1186/s12879-015-0922-z
pubmed: 25884557
pmcid: 4438334
Kim YE, Song M, Lee J et al (2018) Phylogenetic characterization of norovirus strains detected from sporadic gastroenteritis in Seoul during 2014–2016. Gut Pathog 10:36. https://doi.org/10.1186/s13099-018-0263-8
doi: 10.1186/s13099-018-0263-8
pubmed: 30181781
pmcid: 6112129
Ouédraogo N, Kaplon J, Bonkoungou IJ et al (2016) Prevalence and genetic diversity of enteric viruses in children with diarrhea in Ouagadougou, Burkina Faso. PLoS ONE 11(4):e0153652. https://doi.org/10.1371/journal.pone.0153652
doi: 10.1371/journal.pone.0153652
pubmed: 27092779
pmcid: 4836733
Diez-Valcarce M, Lopez MR, Lopez B et al (2019) Prevalence and genetic diversity of viral gastroenteritis viruses in children younger than 5 years of age in Guatemala, 2014–2015. J Clin Virol 114:6–11. https://doi.org/10.1016/j.jcv.2019.03.006
doi: 10.1016/j.jcv.2019.03.006
pubmed: 30875613
pmcid: 8981267
Gupta S, Krishnan A, Sharma S et al (2018) Changing pattern of prevalence, genetic diversity, and mixed infections of viruses associated with acute gastroenteritis in pediatric patients in New Delhi, India. J Med Virol 90(3):469–476. https://doi.org/10.1002/jmv.24980
doi: 10.1002/jmv.24980
pubmed: 29064572
Reymão TKA, Fumian TM, Justino MCA et al (2018) Norovirus RNA in serum associated with increased fecal viral load in children: Detection, quantification and molecular analysis. PLoS ONE 13(7):e0199763. https://doi.org/10.1371/journal.pone.0199763
doi: 10.1371/journal.pone.0199763
pubmed: 29965979
pmcid: 6028094
Paula FL, Sardi SI, Tigre DM et al (2018) Acute gastroenteritis associated with norovirus GII.4 variants. Arq Gastroenterol 55(3):264–266. https://doi.org/10.1590/S0004-2803.201800000-67
doi: 10.1590/S0004-2803.201800000-67
pubmed: 30540089
Gray JJ, Kohli E, Ruggeri FM et al (2007) European multicenter evaluation of commercial enzyme immunoassays for detecting norovirus antigen in fecal samples. Clin Vaccine Immunol 14(10):1349–1355. https://doi.org/10.1128/CVI.00214-07
doi: 10.1128/CVI.00214-07
pubmed: 17715333
pmcid: 2168115
Moyo S, Hanevik K, Blomberg B et al (2014) Genetic diversity of norovirus in hospitalised diarrhoeic children and asymptomatic controls in Dar es Salaam, Tanzania. Infect Genet Evol 26:340–347. https://doi.org/10.1016/j.meegid.2014.06.013
doi: 10.1016/j.meegid.2014.06.013
pubmed: 24960396
Mesquita JR, Nascimento MS (2014) Norovirus GII.4 antibodies in the Portuguese population. J Infect Dev Ctries 8(9):1201–1204. https://doi.org/10.3855/jidc.4616
doi: 10.3855/jidc.4616
pubmed: 25212086
Abugalia M, Cuevas L, Kirby A et al (2011) Clinical features and molecular epidemiology of rotavirus and norovirus infections in Libyan children. J Med Virol 83(10):1849–1856. https://doi.org/10.1002/jmv.22141
doi: 10.1002/jmv.22141
pubmed: 21837804
Mathew S, Alansari K, Smatti M et al (2019) Epidemiological, molecular, and clinical features of norovirus infections among pediatric patients in Qatar. Viruses 11(5):400. https://doi.org/10.3390/v11050400
doi: 10.3390/v11050400
pmcid: 6563317
Eftim SE, Hong T, Soller J et al (2017) Occurrence of norovirus in raw sewage—a systematic literature review and meta-analysis. Water Res 111:366–374. https://doi.org/10.1016/j.watres.2017.01.017
doi: 10.1016/j.watres.2017.01.017
pubmed: 28110140
Fumian TM, Fioretti JM, Lun JH et al (2019) Detection of norovirus epidemic genotypes in raw sewage using next generation sequencing. Environ Int 123:282–291. https://doi.org/10.1016/j.envint.2018.11.054
doi: 10.1016/j.envint.2018.11.054
pubmed: 30553201
Mans J, Murray TY, Taylor MB (2014) Novel norovirus recombinants detected in South Africa. Virol J 11:168. https://doi.org/10.1186/1743-422X-11-168
doi: 10.1186/1743-422X-11-168
pubmed: 25228444
pmcid: 4181420
Bruggink LD, Moselen JM, Marshall JA (2016) The comparative molecular epidemiology of GII.P7_GII.6 and GII.P7_GII.7 norovirus outbreaks in Victoria, Australia, 2012–2014. Intervirology 59(1):60–65. https://doi.org/10.1159/000448100
doi: 10.1159/000448100
pubmed: 27553653
Utsumi T, Lusida MI, Dinana Z et al (2017) Occurrence of norovirus infection in an asymptomatic population in Indonesia. Infect Genet Evol 55:1–7. https://doi.org/10.1016/j.meegid.2017.08.020
doi: 10.1016/j.meegid.2017.08.020
pubmed: 28843544
Volpini LPB, Barreira DMPG, Almeida PLDS et al (2020) An outbreak due to a norovirus GII.Pe-GII.4 Sydney_2012 recombinant in neonatal and pediatric intensive care units. J Infect Public Health 13(1):89–93. https://doi.org/10.1016/j.jiph.2019.06.012
doi: 10.1016/j.jiph.2019.06.012
pubmed: 31281104
Hernandez JDM, Silva LDD, Sousa Junior EC et al (2016) Analysis of uncommon norovirus recombinants from Manaus, Amazon region, Brazil: GII.P22/GII.5, GII.P7/GII.6 and GII.Pg/GII.1. Infect Genet Evol 39:365–371. https://doi.org/10.1016/j.meegid.2016.02.007
doi: 10.1016/j.meegid.2016.02.007
pubmed: 26861619
Cai H, Yu Y, Jin M et al (2017) Cloning, sequencing and characterization of the genome of a recombinant norovirus of the rare genotype GII.P7/GII.6 in China. Arch Virol 162(7):2053–2059. https://doi.org/10.1007/s00705-017-3325-1
doi: 10.1007/s00705-017-3325-1
pubmed: 28299482
Dong X, Qin M, Wang ZE et al (2019) Should we pay attention to recombinant norovirus strain GII.P7/GII.6? J Infect Public Health 12(3):403–409. https://doi.org/10.1016/j.jiph.2018.12.007
doi: 10.1016/j.jiph.2018.12.007
pubmed: 30658905
Fajardo Á, Tort FL, Victoria M et al (2014) Phylogenetic analyses of Norovirus strains detected in Uruguay reveal the circulation of the novel GII.P7/GII.6 recombinant variant. Infect Genet Evol 28:328–332. https://doi.org/10.1016/j.meegid.2014.10.026
doi: 10.1016/j.meegid.2014.10.026
pubmed: 25445648
Puustinen L, Blazevic V, Salminen M et al (2011) Noroviruses as a major cause of acute gastroenteritis in children in Finland, 2009–2010. Scand J Infect Dis 43(10):804–808. https://doi.org/10.3109/00365548.2011.588610
doi: 10.3109/00365548.2011.588610
pubmed: 21696253
Fumian TM, Andrade JSR, Leite JP et al (2016) Norovirus recombinant strains isolated from gastroenteritis outbreaks in Southern Brazil, 2004–2011. PLoS ONE 11(4):e0145391. https://doi.org/10.1371/journal.pone.0145391
doi: 10.1371/journal.pone.0145391
pubmed: 27116353
pmcid: 4846083
Chan MCW, Hu Y, Chen H et al (2017) Global spread of Norovirus GII.17 Kawasaki 308, 2014–2016. Emerg Infect Dis 23(8):1359–1354. https://doi.org/10.3201/eid2308.161138
doi: 10.3201/eid2308.161138
pubmed: 28726618
Degiuseppe JI, Gomes KA, Hadad MF et al (2017) Detection of novel GII.17 norovirus in Argentina, 2015. Infect Genet Evol 47:121–124. https://doi.org/10.1016/j.meegid.2016.11.026
doi: 10.1016/j.meegid.2016.11.026
pubmed: 27908796
Silva LD, Bandeira RD, Junior EC et al (2017) Detection and genetic characterization of the emergent GII.17_2014 norovirus genotype among children with gastroenteritis from Northern Brazil. Infect Genet Evol 48:1–3. https://doi.org/10.1016/j.meegid.2016.11.027
doi: 10.1016/j.meegid.2016.11.027
pubmed: 27923768
Medici MC, Tummolo F, Martella V et al (2014) Novel recombinant GII.P16_GII.13 and GII.P16_GII.3 norovirus strains in Italy. Virus Res 188:142–145. https://doi.org/10.1016/j.virusres.2014.04.005
doi: 10.1016/j.virusres.2014.04.005
pubmed: 24751799
Medici MC, Tummolo F, Martella V et al (2018) Emergence of novel recombinant GII.P16_GII.2 and GII.P16_GII.4 Sydney 2012 norovirus strains in Italy, winter 2016/2017. New Microbiol 41(1):71–72
pubmed: 29505067
Pabbaraju K, Wong AA, Tipples GA et al (2019) Emergence of a novel recombinant norovirus GII.P16-GII.12 strain causing gastroenteritis, Alberta, Canada. Emerg Infect Dis 25(8):1556–1559. https://doi.org/10.3201/eid2508.190059
doi: 10.3201/eid2508.190059
pubmed: 31310222
pmcid: 6649330
Hoffmann D, Mauroy A, Seebach J et al (2013) New norovirus classified as a recombinant GII.g/GII.1 causes an extended foodborne outbreak at a university hospital in Munich. J Clin Virol 58(1):24–30. https://doi.org/10.1016/j.jcv.2013.06.018
doi: 10.1016/j.jcv.2013.06.018
pubmed: 23849648
Nahar S, Afrad MH, Begum N et al (2013) High prevalence of noroviruses among hospitalized diarrheal patients in Bangladesh, 2011. J Infect Dev Ctries 7(11):892–896. https://doi.org/10.3855/jidc.2944
doi: 10.3855/jidc.2944
pubmed: 24240050
Arana A, Cilla G, Montes M et al (2014) Genotypes, recombinant forms, and variants of norovirus GII.4 in Gipuzkoa (Basque Country, Spain), 2009–2012. PLoS ONE 9(6):e98875. https://doi.org/10.1371/journal.pone.0098875
doi: 10.1371/journal.pone.0098875
pubmed: 24893307
pmcid: 4043750
Iritani N, Kaida A, Abe N et al (2012) Increase of GII.2 norovirus infections during the 2009–2010 season in Osaka City, Japan. J Med Virol. 84(3):517–525. https://doi.org/10.1002/jmv.23211
doi: 10.1002/jmv.23211
pubmed: 22246841
Wang YH, Zhou DJ, Zhou X et al (2012) Molecular epidemiology of noroviruses in children and adults with acute gastroenteritis in Wuhan, China, 2007–2010. Arch Virol. 157(12):2417–2424. https://doi.org/10.1007/s00705-012-1437-1
doi: 10.1007/s00705-012-1437-1
pubmed: 22886184
Bidalot M, Théry L, Kaplon J et al (2017) Emergence of new recombinant noroviruses GII.p16-GII.4 and GII.p16-GII.2, France, winter 2016 to 2017. Euro Surveill 22(15):30508. https://doi.org/10.2807/1560-7917.ES.2017.22.15.30508
doi: 10.2807/1560-7917.ES.2017.22.15.30508
pubmed: 28449729
pmcid: 5476982
Ao Y, Xie X, Dong X et al (2019) Genetic analysis of an emerging GII.P2-GII.2 norovirus associated with a 2016 outbreak of acute gastroenteritis in China. Virol Sin 34(1):111–114. https://doi.org/10.1007/s12250-019-00084-6
doi: 10.1007/s12250-019-00084-6
pubmed: 30725317
pmcid: 6420544
Liu LT, Kuo TY, Wu CY et al (2017) Recombinant GII.P16-GII.2 Norovirus, Taiwan, 2016. Emerg Infect Dis 23(7):1180–1183. https://doi.org/10.3201/eid2307.170212
doi: 10.3201/eid2307.170212
pubmed: 28585917
pmcid: 5512481
Niendorf S, Jacobsen S, Faber M et al (2017) Steep rise in norovirus cases and emergence of a new recombinant strain GII.P16-GII.2, Germany, winter 2016. Euro Surveill 22(4):30447. https://doi.org/10.2807/1560-7917.ES.2017.22.4.30447
doi: 10.2807/1560-7917.ES.2017.22.4.30447
pubmed: 28181902
pmcid: 5388089
Cheung SKC, Kwok K, Zhang LY et al (2019) Higher viral load of emerging norovirus GII.P16-GII.2 than pandemic GII.4 and epidemic GII.17, Hong Kong, China. Emerg Infect Dis 25(1):119–122. https://doi.org/10.3201/eid2501.180395
doi: 10.3201/eid2501.180395
pubmed: 30561298
pmcid: 6302574
Mizukoshi F, Nagasawa K, Doan YH et al (2017) Molecular evolution of the RNA-dependent RNA polymerase and capsid genes of human norovirus genotype GII.2 in Japan during 2004–2015. Front Microbiol 8:705. https://doi.org/10.3389/fmicb.2017.00705
doi: 10.3389/fmicb.2017.00705
pubmed: 28487679
pmcid: 5403926
Silva-Sales M, Leal E, Milagres FAP, Brustulin R, Morais VDS, Marcatti R, Araújo ELL, Witkin SS, Deng X, Sabino EC, Delwart E, Luchs A, Costa ACD (2020 Dec) Genomic constellation of human Rotavirus A strains identified in Northern Brazil: a 6-year follow-up (2010–2016). Rev Inst Med Trop Sao Paulo. 18(62):e98. https://doi.org/10.1590/S1678-9946202062098
doi: 10.1590/S1678-9946202062098