Resveratrol supplementation and acute pancreatitis: A comprehensive review.
Acute pancreatitis
Inflammation
Oxidative stress
Resveratrol
Journal
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
ISSN: 1950-6007
Titre abrégé: Biomed Pharmacother
Pays: France
ID NLM: 8213295
Informations de publication
Date de publication:
May 2021
May 2021
Historique:
received:
29
09
2020
revised:
07
01
2021
accepted:
10
01
2021
pubmed:
26
1
2021
medline:
20
7
2021
entrez:
25
1
2021
Statut:
ppublish
Résumé
Resveratrol, a natural polyphenolic ingredient extracted from herbs, suppresses oxidative stress and inflammation. We performed a comprehensive review to find any evidence about the effects of Resveratrol on acute pancreatitis (AP). Resveratrol has been found to directly impact cytokine generation. As these factors play a crucial role in the pathophysiology of AP, resveratrol might attenuate AP and its complications. Mechanistically, resveratrol exerts its pharmacological effects through anti-inflammatory and antioxidant mechanisms via interaction with different signaling molecules and transcription factors. Indeed, resveratrol might prove to be an effective therapeutic component for AP treatment in the future. In this review, we shed light on potential most recent pathways through which resveratrol might impact the management and control of AP.
Identifiants
pubmed: 33493966
pii: S0753-3322(21)00053-6
doi: 10.1016/j.biopha.2021.111268
pii:
doi:
Substances chimiques
Anti-Inflammatory Agents
0
Antioxidants
0
Inflammation Mediators
0
Resveratrol
Q369O8926L
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
111268Informations de copyright
Copyright © 2021. Published by Elsevier Masson SAS.