Metabolism of Zearalenone in the Rumen of Dairy Cows with and without Application of a Zearalenone-Degrading Enzyme.


Journal

Toxins
ISSN: 2072-6651
Titre abrégé: Toxins (Basel)
Pays: Switzerland
ID NLM: 101530765

Informations de publication

Date de publication:
22 01 2021
Historique:
received: 18 11 2020
revised: 14 01 2021
accepted: 20 01 2021
entrez: 27 1 2021
pubmed: 28 1 2021
medline: 2 7 2021
Statut: epublish

Résumé

The mycotoxin zearalenone (ZEN) is a frequent contaminant of animal feed and is well known for its estrogenic effects in animals. Cattle are considered less sensitive to ZEN than pigs. However, ZEN has previously been shown to be converted to the highly estrogenic metabolite α-zearalenol (α-ZEL) in rumen fluid in vitro. Here, we investigate the metabolism of ZEN in the reticulorumen of dairy cows. To this end, rumen-fistulated non-lactating Holstein Friesian cows (

Identifiants

pubmed: 33499402
pii: toxins13020084
doi: 10.3390/toxins13020084
pmc: PMC7911295
pii:
doi:

Substances chimiques

zearalenol 0
Zearalenone 5W827M159J
Zeranol 76LO2L2V39
Hydrolases EC 3.-

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

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Auteurs

Christiane Gruber-Dorninger (C)

BIOMIN Research Center, BIOMIN Holding GmbH, 3430 Tulln, Austria.

Johannes Faas (J)

BIOMIN Research Center, BIOMIN Holding GmbH, 3430 Tulln, Austria.

Barbara Doupovec (B)

BIOMIN Research Center, BIOMIN Holding GmbH, 3430 Tulln, Austria.

Markus Aleschko (M)

BIOMIN Research Center, BIOMIN Holding GmbH, 3430 Tulln, Austria.

Christian Stoiber (C)

BIOMIN Research Center, BIOMIN Holding GmbH, 3430 Tulln, Austria.

Andreas Höbartner-Gußl (A)

BIOMIN Research Center, BIOMIN Holding GmbH, 3430 Tulln, Austria.

Karin Schöndorfer (K)

BIOMIN Research Center, BIOMIN Holding GmbH, 3430 Tulln, Austria.

Manuela Killinger (M)

BIOMIN Research Center, BIOMIN Holding GmbH, 3430 Tulln, Austria.

Qendrim Zebeli (Q)

Institute of Animal Nutrition and Functional Plant Compounds, Department for Farm Animals and Veterinary Public Health, University of Veterinary Medicine Vienna, 1210 Vienna, Austria.

Dian Schatzmayr (D)

BIOMIN Research Center, BIOMIN Holding GmbH, 3430 Tulln, Austria.

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Classifications MeSH